Catalog No.
YHC21901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly560-Asp744
Predicted molecular weight
22.94 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06756
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MSK8, VNRA, Vitronectin receptor, Integrin alpha-V, Vitronectin receptor subunit alpha, CD51, ITGAV, VTNR
A proteogenomic tool uncovers protein markers for human microglial states., PMID:40236015
Evaluation of Novel Therapeutic Agents for Modulation of the Inflammatory Response in Rotator Cuff Tendinopathy Utilizing a Mouse Model of Subacromial Impingement., PMID:40159684
Osteopontin inhibits autophagy via CD44 and avβ3 integrin and promotes cell proliferation in osteoarthritic fibroblast-like synoviocytes., PMID:40102843
Comprehensive analysis of the multifaceted role of ITGAV in digestive system cancer progression and immune infiltration., PMID:40018050
Vitronectin stimulates hepatic gluconeogenesis by activating the cAMP/PKA/CREB axis in the liver., PMID:39909307
Characterisation and hierarchy of the spermatogonial stem cell compartment in human spermatogenesis by spectral cytometry using a 16-colors panel., PMID:39725808
Itm2a expression marks periosteal skeletal stem cells that contribute to bone fracture healing., PMID:39225088
Vitronectin promotes insulin resistance in trophoblast cells by activating JNK in gestational diabetes mellitus., PMID:38654431
Anti-rheumatoid arthritis potential of Halodule pinifolia: development, characterization and in vivo evaluation of H. pinifolia-based oral suspension and lipid nano-emulsion., PMID:38451395
Direct Reprogramming of Hepatocytes Into JAK/Stat-Dependent LGR5+ Liver Cells Able to Initiate Intrahepatic Cholangiocarcinoma., PMID:38262709
Semaphorin 7A is protective during inflammatory peritonitis through integrin receptor signaling., PMID:38094294
Kunitz-type protease inhibitor TFPI2 remodels stemness and immunosuppressive tumor microenvironment in glioblastoma., PMID:37667051
Combined inhibition of surface CD51 and γ-secretase-mediated CD51 cleavage improves therapeutic efficacy in experimental metastatic hepatocellular carcinoma., PMID:37604269
Bone on-a-chip: a 3D dendritic network in a screening platform for osteocyte-targeted drugs., PMID:37552982
Expression and function of CD51 on CD8 T cells as an immunomodulatory target., PMID:37087799
Effects of aging and macrophages on mice stem Leydig cell proliferation and differentiation in vitro., PMID:37051204
Impaired function of skeletal stem cells derived from growth plates in ovariectomized mice., PMID:36847866
Optically driven microtools with an antibody-immobilised surface for on-site cell assembly., PMID:36647211
Controlled Release of Bone Morphogenetic Protein-2 Augments the Coupling of Angiogenesis and Osteogenesis for Accelerating Mandibular Defect Repair., PMID:36365215
In vitro assessment of varying peptide surface density on the suppression of angiogenesis by micelles displaying αvβ3 blocking peptides., PMID:36054456
OPN inhibits autophagy through CD44, integrin and the MAPK pathway in osteoarthritic chondrocytes., PMID:36034459
Glycan Epitope and Integrin Expression Dynamics Characterize Neural Crest Epithelial-to-Mesenchymal Transition (EMT) in Human Pluripotent Stem Cell Differentiation., PMID:35727432
Pulsed Electric Field Treatments with Nonlethal Field Strength Alter the Properties of Bacterial Spores., PMID:35512130
Generation of a BAC transgenic mouse strain that expresses CreERT and a fluorescent protein under the transcriptional control of the Fzd5 locus., PMID:35227325
A defective lysophosphatidic acid-autophagy axis increases miscarriage risk by restricting decidual macrophage residence., PMID:35220880
Ozone-induced changes in the murine lung extracellular vesicle small RNA landscape., PMID:34558223
Orthogonal targeting of osteoclasts and myeloma cells for radionuclide stimulated dynamic therapy induces multidimensional cell death pathways., PMID:34335961
Search for Novel Plasma Membrane Proteins as Potential Biomarkers in Human Mesenchymal Stem Cells Derived from Dental Pulp, Adipose Tissue, Bone Marrow, and Hair Follicle., PMID:34230997
Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression., PMID:34174926
Cardiac Derived CD51-Positive Mesenchymal Stem Cells Enhance the Cardiac Repair Through SCF-Mediated Angiogenesis in Mice With Myocardial Infarction., PMID:33968928
CD271+CD51+PALLADIN- Human Mesenchymal Stromal Cells Possess Enhanced Ossicle-Forming Potential., PMID:33926240
Insights into the Regulation on Proliferation and Differentiation of Stem Leydig Cells., PMID:33598893
Immunological features of circulating monocyte subsets in patients with squamous cell carcinoma of the head and neck., PMID:33476742
RNA sequencing data from osteochondroprogenitor populations in synovial joints of mice during murine model of rheumatoid arthritis., PMID:33304967
Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45- TER119-Erythroid and Lymphoid Progenitors., PMID:33103089
Anti-integrin αv therapy improves cardiac fibrosis after myocardial infarction by blunting cardiac PW1+ stromal cells., PMID:32647159
CD51 distinguishes a subpopulation of bone marrow mesenchymal stem cells with distinct migratory potential: a novel cell-based strategy to treat acute myocardial infarction in mice., PMID:31747966
Mesenchymal stromal cells lower platelet activation and assist in platelet formation in vitro., PMID:31434805
Characteristics of Natural Killer Cell Interaction with Trophoblast Cells During Pregnancy., PMID:31393246
A population of nonneuronal GFRα3-expressing cells in the bone marrow resembles nonmyelinating Schwann cells., PMID:31302761
Lineage marker expression on mouse hematopoietic stem cells., PMID:31299288
Cell-derived microvesicles in infective endocarditis: Role in diagnosis and potential for risk stratification at hospital admission., PMID:31207323
Macrophage-expressed CD51 promotes cancer stem cell properties via the TGF-β1/smad2/3 axis in pancreatic cancer., PMID:31199988
Characterization and differentiation of CD51+ Stem Leydig cells in adult mouse testes., PMID:31102608
Targeted delivery of p-coumaric acid encapsulated mannosylated liposomes to the synovial macrophages inhibits osteoclast formation and bone resorption in the rheumatoid arthritis animal model., PMID:30339889
The Majority of CD45- Ter119- CD31- Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors., PMID:30314756
CD51 is an independent unfavorable prognostic factor in esophageal squamous cell carcinoma., PMID:30049512
Switching from reference infliximab to CT-P13 in patients with inflammatory bowel disease: results of a multicenter study after 12 months., PMID:29893581
p53-dependent CD51 expression contributes to characteristics of cancer stem cells in prostate cancer., PMID:29743605
The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair., PMID:29556234
For research use only. Not for human or drug use.
