Anti-RAD21 Antibody (R1E45)

Catalog No.

RHA83001

Species reactivity

Human, Hamster

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000

Target

SCC1, RAD21, KIAA0078, Nuclear matrix protein 1, Double-strand-break repair protein rad21 homolog, NXP1, SCC1 homolog, 64-kDa carboxy-terminal product, 65-kDa carboxy-terminal product, hHR21, HR21, NXP-1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O60216

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1E45

Molecular Profile and Matched Targeted Therapy for Advanced Breast Cancer Patients., PMID:36826152

Mapping separase-mediated cleavage in situ., PMID:36415827

Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells., PMID:34465007

RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones., PMID:30850627

The cohesin complex prevents Myc-induced replication stress., PMID:28749464

PBMC transcriptome profiles identifies potential candidate genes and functional networks controlling the innate and the adaptive immune response to PRRSV vaccine in Pietrain pig., PMID:28278192

Cell Division Cycle 6 Promotes Mitotic Slippage and Contributes to Drug Resistance in Paclitaxel-Treated Cancer Cells., PMID:27611665

Cell Killing Mechanisms and Impact on Gene Expression by Gemcitabine and 212Pb-Trastuzumab Treatment in a Disseminated i.p. Tumor Model., PMID:27467592

Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination., PMID:27264181

Impact of α-targeted radiation therapy on gene expression in a pre-clinical model for disseminated peritoneal disease when combined with paclitaxel., PMID:25268703

Identification and Characterization of Separase Inhibitors (Sepins) for Cancer Therapy., PMID:24525869

Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells., PMID:23962039

Deep sequencing of the murine IgH repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies., PMID:23898036

Cellular localization of mitotic RAD21 with repetitive amino acid motifs in Allium cepa., PMID:23201414

A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection., PMID:23010778

CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells., PMID:21606361

The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells., PMID:21349430

Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development., PMID:19109133

Cut1/separase-dependent roles of multiple phosphorylation of fission yeast cohesion subunit Rad21 in post-replicative damage repair and mitosis., PMID:18239448

The complete removal of cohesin from chromosome arms depends on separase., PMID:18003702

OsRAD21-3, an orthologue of yeast RAD21, is required for pollen development in Oryza sativa., PMID:17617177

Chromosome elimination in the interspecific hybrid medaka between Oryzias latipes and O. hubbsi., PMID:17603754

Mammalian SGO2 appears at the inner centromere domain and redistributes depending on tension across centromeres during meiosis II and mitosis., PMID:17205076

Cohesion proteins are present in centromere protein bodies associated with avian lampbrush chromosomes., PMID:16235117

Changes in the expression and localization of cohesin subunits during meiosis in a non-mammalian vertebrate, the medaka fish., PMID:15261826

Cohesin component dynamics during meiotic prophase I in mammalian oocytes., PMID:15125634

Temporally and spatially selective loss of Rec8 protein from meiotic chromosomes during mammalian meiosis., PMID:12759374

STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis., PMID:12034751

A potential role for human cohesin in mitotic spindle aster assembly., PMID:11590136

A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction., PMID:11390355

Human chromatid cohesin component hRad21 is phosphorylated in M phase and associated with metaphase centromeres., PMID:11073952

NXP-1, a human protein related to Rad21/Scc1/Mcd1, is a component of the nuclear matrix., PMID:10623634

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