Catalog No.
RHA78202
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
Roadkill homolog 1, HIB homolog 1, SPOP, Speckle-type POZ protein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O43791
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1E34
Network Medicine-Based Strategy Identifies Maprotiline as a Repurposable Drug by Inhibiting PD-L1 Expression via Targeting SPOP in Cancer., PMID:39499771
Targeting Nuclear Receptor Coactivator SRC-1 Prevents Colorectal Cancer Immune Escape by Reducing Transcription and Protein Stability of PD-L1., PMID:38953362
Neural Stem Cell Extracellular Vesicles Carrying YBX1 Inhibited Neuronal Pyroptosis Through Increasing m6A-modified GPR30 Stability and Expression in Ischemic Stroke., PMID:37966628
Role of PCIF1-mediated 5'-cap N6-methyladeonsine mRNA methylation in colorectal cancer and anti-PD-1 immunotherapy., PMID:36514940
BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade., PMID:34615996
The establishment of an immunosensor for the detection of SPOP., PMID:34131189
Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression., PMID:34026438
Loss of Speckle-Type POZ Protein Promotes Prostate Cancer Cell Migration and Invasion Through Upregulation of MCP-1., PMID:33872295
NCOR1 may be a potential biomarker of a novel molecular subtype of prostate cancer., PMID:33058520
Rho-associated protein kinase-dependent moesin phosphorylation is required for PD-L1 stabilization in breast cancer., PMID:32941674
ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer., PMID:31772275
Prostate Cancer-associated SPOP mutations enhance cancer cell survival and docetaxel resistance by upregulating Caprin1-dependent stress granule assembly., PMID:31771591
Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer., PMID:29906450
Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients., PMID:26863016
Nanobody-targeted E3-ubiquitin ligase complex degrades nuclear proteins., PMID:26373678
Speckle-type POZ protein, SPOP, is involved in the DNA damage response., PMID:24451148
Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation., PMID:20154143
For research use only. Not for human or drug use.
