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Anti-FOXO3 Antibody (R1E11)

Catalog #:   RHA69803 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, WB
Accession: O43524
Overview

Catalog No.

RHA69803

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, WB: 1:1000-1:2000

Target

Forkhead in rhabdomyosarcoma-like 1, AF6q21 protein, Forkhead box protein O3, FOXO3, FKHRL1, FOXO3A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O43524

Applications

IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1E11

Data Image
  • Immunofluorescence
    Immunofluorescent analysis of Hela cells, using FoxO3a Antibody.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of FOXO3A expression in MCF-7 cell lysate.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
References

An anti-FAP-scFv-functionalized exosome-carrying hydrogel delivers SKI mRNA to fibrotic nucleus pulposus cells to alleviate intervertebral disc degeneration by regulating FOXO3., PMID:40213661

Role of FOXO3a in LPS-induced inflammatory conditions in human dental pulp cells., PMID:39824385

Bisphenol A-induced oxidative stress increases the production of ovarian cancer stem cells in mice., PMID:39322090

CTLA4-Ig protects tacrolimus-induced oxidative stress via inhibiting the AKT/FOXO3 signaling pathway in rats., PMID:37157174

FOXO3 Depletion as a Marker of Compression-Induced Apoptosis in the Ligature Mark: An Immunohistochemical Study., PMID:36674912

A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis., PMID:36456730

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3., PMID:36252111

The hippo kinase MST1 negatively regulates the differentiation of follicular helper T cells., PMID:36210514

Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis., PMID:35491858

Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis., PMID:35370755

Dynamics of AQP4 upon exposure to seropositive patient serum before and after Rituximab therapy in Neuromyelitis Optica: A cell-based study., PMID:34715591

MicroRNA 195-5p Targets Foxo3 Promoter Region to Regulate Its Expression in Granulosa Cells., PMID:34201585

Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer., PMID:33976188

B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition., PMID:33853871

Free CA125 promotes ovarian cancer cell migration and tumor metastasis by binding Mesothelin to reduce DKK1 expression and activate the SGK3/FOXO3 pathway., PMID:33613114

Upregulation of FoxO3a expression through PI3K/Akt pathway attenuates the progression of lupus nephritis in MRL/lpr mice., PMID:33039957

EpCAM Signaling Promotes Tumor Progression and Protein Stability of PD-L1 through the EGFR Pathway., PMID:32978170

FOXO3a accumulation and activation accelerate oxidative stress-induced podocyte injury., PMID:32786113

SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways., PMID:32619406

Foxo3 Promotes the Differentiation and Function of Follicular Helper T Cells., PMID:32402289

Role of FOXO3A in Trastuzumab Combination Chemotherapy in Esophageal Squamous Cell Carcinoma., PMID:32234881

CD28-Dependent CTLA-4 Expression Fine-Tunes the Activation of Human Th17 Cells., PMID:32203908

A small-molecule inhibitor of PCSK9 transcription ameliorates atherosclerosis through the modulation of FoxO1/3 and HNF1α., PMID:32058941

The glucocorticoid-induced leucine zipper mediates statin-induced muscle damage., PMID:32030813

CXCL16/CXCR6 axis promotes bleomycin-induced fibrotic process in MRC-5 cells via the PI3K/AKT/FOXO3a pathway., PMID:31753588

PBMCs transcriptome profiles identified breed-specific transcriptome signatures for PRRSV vaccination in German Landrace and Pietrain pigs., PMID:31536525

FOXO3 Is Expressed in Ovarian Tissues and Acts as an Apoptosis Initiator in Granulosa Cells of Chickens., PMID:31380433

Molecular Profiling of Inflammatory Bowel Disease: Is It Ready for Use in Clinical Decision-Making?, PMID:31167397

Promyelocytic leukemia protein (PML) controls breast cancer cell proliferation by modulating Forkhead transcription factors., PMID:30927552

Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation., PMID:30815844

SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions., PMID:30774023

Ginkgo biloba Extract Protects Mesenteric Arterioles of Old Rats via Improving Vessel Elasticity through Akt/FoxO3a Signaling Pathway., PMID:30684626

Expression of the Forkhead box transcription factor Foxo3a in human periapical granulomas., PMID:30429437

High-Throughput Image-Based Screening to Identify Chemical Compounds Capable of Activating FOXO., PMID:30414152

Characterization of FOXO Acetylation., PMID:30414146

Effect of oral isotretinoin on the nucleo-cytoplasmic distribution of FoxO1 and FoxO3 proteins in sebaceous glands of patients with acne vulgaris., PMID:30240097

Foxo3 Promotes Apoptosis of B Cell Receptor-Stimulated Immature B Cells, Thus Limiting the Window for Receptor Editing., PMID:29950509

Copper nanoparticles induce early fibrotic changes in the liver via TGF-β/Smad signaling and cause immunosuppressive effects in rats., PMID:29848140

FoxO3a Regulates Inflammation-induced Autophagy in Odontoblasts., PMID:29551204

The Role of Forkhead Box 1 (FOXO1) in the Immune System: Dendritic Cells, T Cells, B Cells, and Hematopoietic Stem Cells., PMID:29431075

Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells., PMID:29301589

SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway., PMID:29017179

[Preparation and characterization of mouse polyclonal antibody against conserved region of human FOXO3]., PMID:28615107

Mycoplasma fermentans deacetylase promotes mammalian cell stress tolerance., PMID:28602396

AKT2 Regulates Pulmonary Inflammation and Fibrosis via Modulating Macrophage Activation., PMID:28455433

Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway., PMID:28407698

Comparative and temporal transcriptome analysis of peste des petits ruminants virus infected goat peripheral blood mononuclear cells., PMID:28017736

Evaluation of the p-AKT, p-JNK and FoxO3a function in oral epithelial dysplasia., PMID:27976455

FoxO3a confers cetuximab resistance in RAS wild-type metastatic colorectal cancer through c-Myc., PMID:27825133

Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis., PMID:27214848

Datasheet

Document Download

Anti-FOXO3 Antibody (R1E11).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-FOXO3 Antibody (R1E11) [RHA69803]
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