Catalog No.
RHA69803
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, WB: 1:1000-1:2000
Target
Forkhead in rhabdomyosarcoma-like 1, AF6q21 protein, Forkhead box protein O3, FOXO3, FKHRL1, FOXO3A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O43524
Applications
IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1E11
An anti-FAP-scFv-functionalized exosome-carrying hydrogel delivers SKI mRNA to fibrotic nucleus pulposus cells to alleviate intervertebral disc degeneration by regulating FOXO3., PMID:40213661
Role of FOXO3a in LPS-induced inflammatory conditions in human dental pulp cells., PMID:39824385
Bisphenol A-induced oxidative stress increases the production of ovarian cancer stem cells in mice., PMID:39322090
CTLA4-Ig protects tacrolimus-induced oxidative stress via inhibiting the AKT/FOXO3 signaling pathway in rats., PMID:37157174
FOXO3 Depletion as a Marker of Compression-Induced Apoptosis in the Ligature Mark: An Immunohistochemical Study., PMID:36674912
A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis., PMID:36456730
Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3., PMID:36252111
The hippo kinase MST1 negatively regulates the differentiation of follicular helper T cells., PMID:36210514
Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis., PMID:35491858
Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis., PMID:35370755
Dynamics of AQP4 upon exposure to seropositive patient serum before and after Rituximab therapy in Neuromyelitis Optica: A cell-based study., PMID:34715591
MicroRNA 195-5p Targets Foxo3 Promoter Region to Regulate Its Expression in Granulosa Cells., PMID:34201585
Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer., PMID:33976188
B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition., PMID:33853871
Free CA125 promotes ovarian cancer cell migration and tumor metastasis by binding Mesothelin to reduce DKK1 expression and activate the SGK3/FOXO3 pathway., PMID:33613114
Upregulation of FoxO3a expression through PI3K/Akt pathway attenuates the progression of lupus nephritis in MRL/lpr mice., PMID:33039957
EpCAM Signaling Promotes Tumor Progression and Protein Stability of PD-L1 through the EGFR Pathway., PMID:32978170
FOXO3a accumulation and activation accelerate oxidative stress-induced podocyte injury., PMID:32786113
SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways., PMID:32619406
Foxo3 Promotes the Differentiation and Function of Follicular Helper T Cells., PMID:32402289
Role of FOXO3A in Trastuzumab Combination Chemotherapy in Esophageal Squamous Cell Carcinoma., PMID:32234881
CD28-Dependent CTLA-4 Expression Fine-Tunes the Activation of Human Th17 Cells., PMID:32203908
A small-molecule inhibitor of PCSK9 transcription ameliorates atherosclerosis through the modulation of FoxO1/3 and HNF1α., PMID:32058941
The glucocorticoid-induced leucine zipper mediates statin-induced muscle damage., PMID:32030813
CXCL16/CXCR6 axis promotes bleomycin-induced fibrotic process in MRC-5 cells via the PI3K/AKT/FOXO3a pathway., PMID:31753588
PBMCs transcriptome profiles identified breed-specific transcriptome signatures for PRRSV vaccination in German Landrace and Pietrain pigs., PMID:31536525
FOXO3 Is Expressed in Ovarian Tissues and Acts as an Apoptosis Initiator in Granulosa Cells of Chickens., PMID:31380433
Molecular Profiling of Inflammatory Bowel Disease: Is It Ready for Use in Clinical Decision-Making?, PMID:31167397
Promyelocytic leukemia protein (PML) controls breast cancer cell proliferation by modulating Forkhead transcription factors., PMID:30927552
Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation., PMID:30815844
SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions., PMID:30774023
Ginkgo biloba Extract Protects Mesenteric Arterioles of Old Rats via Improving Vessel Elasticity through Akt/FoxO3a Signaling Pathway., PMID:30684626
Expression of the Forkhead box transcription factor Foxo3a in human periapical granulomas., PMID:30429437
High-Throughput Image-Based Screening to Identify Chemical Compounds Capable of Activating FOXO., PMID:30414152
Characterization of FOXO Acetylation., PMID:30414146
Effect of oral isotretinoin on the nucleo-cytoplasmic distribution of FoxO1 and FoxO3 proteins in sebaceous glands of patients with acne vulgaris., PMID:30240097
Foxo3 Promotes Apoptosis of B Cell Receptor-Stimulated Immature B Cells, Thus Limiting the Window for Receptor Editing., PMID:29950509
Copper nanoparticles induce early fibrotic changes in the liver via TGF-β/Smad signaling and cause immunosuppressive effects in rats., PMID:29848140
FoxO3a Regulates Inflammation-induced Autophagy in Odontoblasts., PMID:29551204
The Role of Forkhead Box 1 (FOXO1) in the Immune System: Dendritic Cells, T Cells, B Cells, and Hematopoietic Stem Cells., PMID:29431075
Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells., PMID:29301589
SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway., PMID:29017179
[Preparation and characterization of mouse polyclonal antibody against conserved region of human FOXO3]., PMID:28615107
Mycoplasma fermentans deacetylase promotes mammalian cell stress tolerance., PMID:28602396
AKT2 Regulates Pulmonary Inflammation and Fibrosis via Modulating Macrophage Activation., PMID:28455433
Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway., PMID:28407698
Comparative and temporal transcriptome analysis of peste des petits ruminants virus infected goat peripheral blood mononuclear cells., PMID:28017736
Evaluation of the p-AKT, p-JNK and FoxO3a function in oral epithelial dysplasia., PMID:27976455
FoxO3a confers cetuximab resistance in RAS wild-type metastatic colorectal cancer through c-Myc., PMID:27825133
Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis., PMID:27214848
For research use only. Not for human or drug use.
