Catalog No.
RHA65401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
Tyrosine-protein kinase RIPK2, CARDIAK, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, RICK, RIPK2, CARD-containing IL-1 beta ICE-kinase, Receptor-interacting serine/threonine-protein kinase 2, RIP-like-interacting CLARP kinase, RIP2, Receptor-interacting protein 2, RIP-2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O43353
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1E05
Association of RIPK1 and RIPK2 Gene Polymorphisms with Rheumatoid Arthritis in a Chinese Han Population., PMID:39444708
Simultaneous substrate and ubiquitin modification recognition by bispecific antibodies enables detection of ubiquitinated RIP1 and RIP2., PMID:38227684
Antibody-Proteolysis Targeting Chimera Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 in HER2+ Cell Lines., PMID:37917829
Anti-complement 5 antibody ameliorates antibody-mediated rejection after liver transplantation in rats., PMID:37398677
Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function., PMID:36189261
Lipophosphoglycan From Dermotropic New World Leishmania Upregulates Interleukin-32 and Proinflammatory Cytokines Through TLR4 and NOD2 Receptors., PMID:35402314
Anti-LINGO-1 antibody ameliorates cognitive impairment, promotes adult hippocampal neurogenesis, and increases the abundance of CB1R-rich CCK-GABAergic interneurons in AD mice., PMID:34044148
Expression and Role of Nucleotide-Binding Oligomerization Domain 2 (NOD2) in the Ocular Surface of Murine Dry Eye., PMID:31237655
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure., PMID:30279238
Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity., PMID:29706531
Schisandra chinensis and Its Main Constituent Schizandrin Attenuate Allergic Reactions by Down-Regulating Caspase-1 in Ovalbumin-Sensitized Mice., PMID:28081628
Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1β and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells., PMID:27402699
Peptidoglycan-linked protein A promotes T cell-dependent antibody expansion during Staphylococcus aureus infection., PMID:27140614
Bacterial Muramyl Dipeptide (MDP) Restricts Human Cytomegalovirus Replication via an IFN-β-Dependent Pathway., PMID:26830977
Hydrogen sulfide diminishes the levels of thymic stromal lymphopoietin in activated mast cells., PMID:26791024
The expression of B & T cell activation markers in children's tonsils following live attenuated influenza vaccine., PMID:26148331
The therapeutic efficacy of α-pinene in an experimental mouse model of allergic rhinitis., PMID:25242385
Human procaspase-1 variants with decreased enzymatic activity are associated with febrile episodes and may contribute to inflammation via RIP2 and NF-κB signaling., PMID:24706726
Receptor interacting protein-2 plays a critical role in human lung epithelial cells survival in response to Fas-induced cell-death., PMID:24658576
The β-sitosterol attenuates atopic dermatitis-like skin lesions through down-regulation of TSLP., PMID:24510054
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer., PMID:23281400
The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2., PMID:22484241
The RIPK2 gene: a positional candidate for tick burden supported by genetic associations in cattle and immunological response of knockout mouse., PMID:22314416
Mechanisms of the apoptosis induced by CD176 antibody in human leukemic cells., PMID:21455576
Identification of a regulatory autophosphorylation site in the serine-threonine kinase RIP2., PMID:16824733
For research use only. Not for human or drug use.
