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Anti-PLSCR1 Antibody (R1D61)

Catalog #:   RHA43601 Specific References (20) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: FCM, IF, IP, WB
Accession: O15162
Overview

Catalog No.

RHA43601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000

Target

Mg(2+)-dependent nuclease, Erythrocyte phospholipid scramblase, PLSCR1, PL scramblase 1, Phospholipid scramblase 1, MmTRA1b, Ca(2+)-dependent phospholipid scramblase 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O15162

Applications

FCM, IF, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1D61

Data Image
  • Western blot
    Western blot analysis of Scramblase 1 expression in A431 cell lysate.
References

PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection., PMID:37438530

Quantitative proteomics of differentiated primary bronchial epithelial cells from chronic obstructive pulmonary disease and control identifies potential novel host factors post-influenza A virus infection., PMID:36713229

Defining resistance and tolerance traits in Covid-19: towards a stratified medicine approach., PMID:35686910

Proteomic analysis of neutrophils in ANCA-associated vasculitis reveals a dysregulation in proteinase 3-associated proteins such as annexin-A1 involved in apoptotic cell clearance., PMID:31142442

Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: Identifying DNA methylation signatures associated with interferon-related genes based on ethnicity and SLEDAI., PMID:30301579

Development of a multiplexed tumor-associated autoantibody-based blood test for the detection of colorectal cancer., PMID:29074220

Prediction of response to remission induction therapy by gene expression profiling of peripheral blood in Japanese patients with microscopic polyangiitis., PMID:28569178

Phospholipid scramblase 1 amplifies anaphylactic reactions in vivo., PMID:28282470

Presence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis., PMID:28245862

Comprehensive molecular profiling of the B7 family of immune-regulatory ligands in breast cancer., PMID:27622076

Phospholipid scramblase 1 is required for β2-glycoprotein I binding in hypoxia and reoxygenation-induced endothelial inflammation., PMID:26216936

Targeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell death., PMID:25588716

Antibody against N-terminal domain of phospholipid scramblase 1 induces apoptosis in colorectal cancer cells through the intrinsic apoptotic pathway., PMID:24766818

Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo., PMID:23259795

Phospholipid scramblase 1 expression is enhanced in patients with antiphospholipid syndrome., PMID:22526829

Phospholipid scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells., PMID:22453241

Phospholipid scramblase 1 is secreted by a lipid raft-dependent pathway and interacts with the extracellular matrix protein 1 in the dermal epidermal junction zone of human skin., PMID:20870722

Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis., PMID:17712045

Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR1) co-localize to uropod rafts in formylated Met-Leu-Phe-stimulated neutrophils., PMID:14766753

IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase., PMID:11259432

Datasheet

Document Download

Anti-PLSCR1 Antibody (R1D61).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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For research use only. Not for human or drug use.

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Anti-PLSCR1 Antibody (R1D61) [RHA43601]
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