Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Antibody / Recombinant Antibody

Anti-IKBKB Antibody (R1D37)

Catalog #:   RHA34301 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, WB
Accession: O14920
Overview

Catalog No.

RHA34301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, WB: 1:500-1:1000

Target

IKKB, IKK-beta, Serine/threonine protein kinase IKBKB, I-kappa-B-kinase beta, Inhibitor of nuclear factor kappa-B kinase subunit beta, I-kappa-B kinase 2, IKBKB, IKK-B, NFKBIKB, IKK2, Nuclear factor NF-kappa-B inhibitor kinase beta, IkBKB

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O14920

Applications

IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1D37

Data Image
  • Immunofluorescence
    Immunocytochemistry analysis of IKK beta (green) in U87-MG using IKK beta antibody,and DAPI(blue).
  • Western blot
    Western blot analysis of IKK beta in A549 lysates using IKK beta antibody.
  • Western blot
    Western blot analysis of IKK beta in 3T3 lysates using IKK beta antibody
References

[A novel fully human LAG-3 monoclonal antibody LBL-007 combined with PD-1 antibody inhibits proliferation, migration and invasion of tumor cells via blocking NF-κB pathway]., PMID:40415618

What are mice teaching us about psoriatic arthritis?, PMID:40265275

NF-ΚB Activation as a Key Driver in Chronic Lymphocytic Leukemia Evolution to Richter's Syndrome: Unraveling the Influence of Immune Microenvironment Dynamics., PMID:39596634

A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever., PMID:39524436

Finding NEMO in the thymus., PMID:39432904

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases., PMID:39352576

Associations of TRAF2 (rs867186), TAB2 (rs237025), IKBKB (rs13278372) Polymorphisms and TRAF2, TAB2, IKBKB Protein Levels with Clinical and Morphological Features of Pituitary Adenomas., PMID:39061149

Role of Skewed X-Chromosome Inactivation in Common Variable Immunodeficiency., PMID:38265673

Tubermycin B coated on Galactosylated Chitosan Nanoparticles synthesized by eco-friendly method ameliorates intracellular free radical production and reduces oxidative stress, reducing phosphorylation of IKKα/β/pIкBα/NF-кB pathway., PMID:37843350

Probiotic-fermented Portulaca oleracea L. alleviated DNFB-induced atopic dermatitis by inhibiting the NF-κB signaling pathway., PMID:37156447

ISG20L1 acts as a co-activator of DAPK1 in the activation of the p53-dependent cell death pathway., PMID:36855954

Inflammatory cytokine-enriched microenvironment plays key roles in the development of breast cancers., PMID:36704829

Regulatory effect of IL-38 on NF-κB pathway in systemic lupus erythematosus., PMID:36621308

ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression., PMID:36435834

Asprosin Exacerbates Endothelium Inflammation Induced by Hyperlipidemia Through Activating IKKβ-NF-κBp65 Pathway., PMID:36401667

Resvega, a Nutraceutical Preparation, Affects NFκB Pathway and Prolongs the Anti-VEGF Effect of Bevacizumab in Undifferentiated ARPE-19 Retina Cells., PMID:36233006

Application of an antibody microarray for serum protein profiling of coronary artery stenosis., PMID:36166954

Oral administration of Helianthus annuus leaf extract ameliorates atopic dermatitis by modulation of T cell activity in vivo., PMID:36108372

Rubella Virus Triggers Type I Interferon Antiviral Response in Cultured Human Neural Cells: Involvement in the Control of Viral Gene Expression and Infectious Progeny Production., PMID:36077193

IKBKE and BANK1 Polymorphisms and Clinical Characteristics in Chinese Women with Systemic Lupus Erythematosus., PMID:35930382

Differential Contribution of NF-κB Signaling Pathways to CD4+ Memory T Cell Induced Activation of Endothelial Cells., PMID:35769477

Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failure., PMID:35641486

Functional IKK/NF-κB signaling in pancreatic stellate cells is essential to prevent autoimmune pancreatitis., PMID:35624133

TRAF3 plays a role in lupus nephritis by regulating Th17 cell and Treg cell balance as well as NF-κB signaling pathway in mice., PMID:35416178

Anti-Tn Monoclonal Antibody Ameliorates Hyperoxia-Induced Kidney Injury by Suppressing Oxidative Stress and Inflammation in Neonatal Mice., PMID:34720748

IκB Kinase-β Regulates Neutrophil Recruitment Through Activation of STAT3 Signaling in the Esophagus., PMID:34311141

Therapeutic effects of quinine in a mouse model of atopic dermatitis., PMID:34240224

Humanized anti‑TLR4 monoclonal antibody ameliorates lipopolysaccharide‑related acute kidney injury by inhibiting TLR4/NF‑κB signaling., PMID:34184086

Down-Regulation of LOC645166 in T Cells of Ankylosing Spondylitis Patients Promotes the NF-κB Signaling via Decreasingly Blocking Recruitment of the IKK Complex to K63-Linked Polyubiquitin Chains., PMID:33717069

Icaritin inhibits PD-L1 expression by Targeting Protein IκB Kinase α., PMID:33354776

Reactive Oxygen Species Induce Endothelial Differentiation of Liver Cancer Stem-Like Sphere Cells through the Activation of Akt/IKK Signaling Pathway., PMID:33101583

Autophagic feedback-mediated degradation of IKKα requires CHK1- and p300/CBP-dependent acetylation of p53., PMID:33097607

NeMO mutations: a rare cause of monogenic Behçet-like disease., PMID:32954429

Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma., PMID:32771949

Improving the diagnostic efficiency of primary immunodeficiencies with targeted next-generation sequencing., PMID:32531373

Inhibiting NF-κB Signaling Activation Reduces Retinal Neovascularization by Promoting a Polarization Shift in Macrophages., PMID:32492108

The IKKβ-USP30-ACLY Axis Controls Lipogenesis and Tumorigenesis., PMID:32221968

Small molecule inhibitors of IκB kinase β: A chip-based screening and molecular docking simulation., PMID:32205046

Rab11 activation by Ik2 kinase is required for dendrite pruning in Drosophila sensory neurons., PMID:32059017

Inferring the transcriptional regulatory mechanism of signal-dependent gene expression via an integrative computational approach., PMID:32052437

Successful Allogeneic Stem Cell Transplantation in Nuclear Factor-Kappa B Essential Modulator Deficiency Syndrome After Treosulfan-Based Conditioning: A Case Report., PMID:32035679

T Cell Impairment Is Predictive for a Severe Clinical Course in NEMO Deficiency., PMID:31965418

Infliximab therapy for inflammatory colitis in an infant with NEMO deficiency., PMID:31713830

Hsp-27 and NF-κB pathway is associated with AR/AR-V7 expression in prostate cancer cells., PMID:30807779

Placental Expression of NEMO Protein in Normal Pregnancy and Preeclampsia., PMID:30723530

Engagement of Fas differentially regulates the production of LPS-induced proinflammatory cytokines and type I interferons., PMID:30536547

Cell-Permeable Bicyclic Peptidyl Inhibitors against NEMO-IκB Kinase Interaction Directly from a Combinatorial Library., PMID:30176143

The Glycolytic Enzyme PFKFB3 Controls TNF-α-Induced Endothelial Proinflammatory Responses., PMID:30171427

IKKε aggravates inflammatory response via activation of NF-κB in rheumatoid arthritis., PMID:29687872

Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21., PMID:29667579

Datasheet

Document Download

Anti-IKBKB Antibody (R1D37).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Anti-IKBKB Antibody (R1D37) [RHA34301]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only