Catalog No.
RHA33301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IP: 1:20-1:50, WB: 1:1000-1:2000
Target
SIP1, GEMIN2, Gemin-2, Component of gems 2, SMN-interacting protein 1, Survival of motor neuron protein-interacting protein 1, Gem-associated protein 2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O14893
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1D34
A novel human-specific splice isoform alters the critical C-terminus of Survival Motor Neuron protein., PMID:27481219
The gemin2-binding site on SMN protein: accessibility to antibody., PMID:23939045
Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle., PMID:23221635
The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons., PMID:21389246
Analysis of SMN-neurite granules: Core Cajal body components are absent from SMN-cytoplasmic complexes., PMID:20515655
Enrichment for breast cancer cells with stem/progenitor properties by differential adhesion., PMID:20222827
Transcription factors Snail, Slug, Twist, and SIP1 in spindle cell carcinoma of the head and neck., PMID:19381684
TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition., PMID:17968309
Absence of gemin5 from SMN complexes in nuclear Cajal bodies., PMID:17640370
Gemin8 is required for the architecture and function of the survival motor neuron complex., PMID:17023415
Identification and characterization of the carboxy-terminal region of Sip-1, a novel autoantigen in Behçet's disease., PMID:16611372
Regulation of vimentin by SIP1 in human epithelial breast tumor cells., PMID:16568083
Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins., PMID:16301532
Unrip is a component of SMN complexes active in snRNP assembly., PMID:15848170
Ultrastructural characterisation of a nuclear domain highly enriched in survival of motor neuron (SMN) protein., PMID:14697339
Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component., PMID:11748230
Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins., PMID:10942426
Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli., PMID:10725331
Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems., PMID:10601333
The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body., PMID:10562276
Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy., PMID:10556282
The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis., PMID:9323130
For research use only. Not for human or drug use.
