Catalog No.
RMA51401
Species reactivity
Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
API4, Apoptosis inhibitor survivin, BIRC 5, EPR 1, IAP4, SVV, TIAP, Survivin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O70201
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1C18
Nanobody-based double antibody sandwich colloidal gold test strips for rapid detection of urinary biomarkers NMP22 and survivin in bladder cancer., PMID:40300312
Shear stress preconditioning enhances periodontal ligament stem cell survival., PMID:40086040
NUPR1 contributes to endocrine therapy resistance by modulating BIRC5 expression and inducing luminal B-ERBB2+ subtype-like characteristics in estrogen receptor-positive breast cancer cells., PMID:39991577
Comparison of Survivin Determination by Surface-Enhanced Fluorescence and Raman Spectroscopy on Nanostructured Silver Substrates., PMID:39451692
SIRT6 suppresses colon cancer growth by inducing apoptosis and autophagy through transcriptionally down-regulating Survivin., PMID:38986922
Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects., PMID:38972347
Anti-BIRC5 autoantibody serves as a valuable biomarker for diagnosing AFP-negative hepatocellular carcinoma., PMID:38832035
Unveiling the Molecular Mechanism of Trastuzumab Resistance in SKBR3 and BT474 Cell Lines for HER2 Positive Breast Cancer., PMID:38534787
Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life., PMID:37938347
In Silico Evaluation of HN-N07 Small Molecule as an Inhibitor of Angiogenesis and Lymphangiogenesis Oncogenic Signatures in Non-Small Cell Lung Cancer., PMID:37509650
ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies., PMID:37294945
N-extended photoprotein obelin to competitively detect small protein tumor markers., PMID:35151206
High ETV6 Levels Support Aggressive B Lymphoma Cell Survival and Predict Poor Outcome in Diffuse Large B-Cell Lymphoma Patients., PMID:35053500
Peripheral tolerance by Treg via constraining OX40 signal in autoreactive T cells against desmoglein 3, a target antigen in pemphigus., PMID:34848535
Ginsenoside Rb1 Lessens Gastric Precancerous Lesions by Interfering With β-Catenin/TCF4 Interaction., PMID:34594214
Diagnostic Utility of BAP1, EZH2 and Survivin in Differentiating Pleural Epithelioid Mesothelioma and Reactive Mesothelial Hyperplasia: Immunohistochemical Study., PMID:34257556
Prognostic significance of survivin expression in pediatric ewing sarcoma., PMID:34076538
Targeted RNAi of BIRC5/Survivin Using Antibody-Conjugated Poly(Propylene Imine)-Based Polyplexes Inhibits Growth of PSCA-Positive Tumors., PMID:34066833
Comparative evaluation of survivin expression in leukoplakia, lichen planus, and oral squamous cell carcinoma: An immunohistochemical study., PMID:32719269
Rapid noninvasive detection of bladder cancer using survivin antibody-conjugated gold nanoparticles (GNPs) based on localized surface plasmon resonance (LSPR)., PMID:32350593
Diagnostic Role of Survivin in Rheumatoid Arthritis: A Systematic Review., PMID:31951186
Surface plasmon resonance immunosensor for label-free detection of BIRC5 biomarker in spontaneously occurring canine mammary tumours., PMID:31530877
High throughput development of TCR-mimic antibody that targets survivin-2B80-88/HLA-A*A24 and its application in a bispecific T-cell engager., PMID:31285464
Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer., PMID:30736848
Down-regulation and nuclear localization of survivin by sodium butyrate induces caspase-dependent apoptosis in human oral mucoepidermoid carcinoma., PMID:30616788
PI3-kinase pathway biomarkers in oral cancer and tumor immune cells., PMID:30556200
Clinical significance of plasma anti-TOPO48 autoantibody and blood survivin-expressing circulating cancer cells in patients with early stage endometrial carcinoma., PMID:30341503
Sublytic C5b-9 Induces Glomerular Mesangial Cell Apoptosis Through miR-3546/SOX4/Survivin Axis in Rat Thy-1 Nephritis., PMID:30235450
Deregulation of p53/survivin apoptotic markers correlated to PTEN expression in pterygium neoplastic cells., PMID:30003758
Immunohistochemical Study of Mitosis-regulatory Proteins in Gastroenteropancreatic Neuroendocrine Neoplasms., PMID:29970506
Diagnostic Value of the Survivin Autoantibody in Four Types of Malignancies., PMID:29924656
The Possible Mechanisms of HSV-TK/Hyperthermia Combined with 131I-antiAFPMcAb-GCV Nanospheres to Treat Hepatoma., PMID:29854577
Plasma anti-BIRC5 IgG may be a useful marker for evaluating the prognosis of nonsmall cell lung cancer., PMID:29744296
Evaluation of survivin immunoexpression in the differentiation of high- and low-grade breast ductal carcinoma in situ., PMID:29694611
Enhanced Biosynthesis Performance of Heterologous Proteins in CHO-K1 Cells Using CRISPR-Cas9., PMID:29683658
Detection of survivin expression in bladder cancer and renal cell carcinoma using specific monoclonal antibodies., PMID:29658613
Anti-GD2 Immunoliposomes for Targeted Delivery of the Survivin Inhibitor Sepantronium Bromide (YM155) to Neuroblastoma Tumor Cells., PMID:29516187
Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer., PMID:29409974
Evaluation of a New Survivin ELISA and UBC® Rapid for the Detection of Bladder Cancer in Urine., PMID:29324722
Effects of poly(I:C) and MF59 co-adjuvants on immunogenicity and efficacy of survivin polypeptide immunogen against melanoma., PMID:29206298
Survivin improves the early recognition of rheumatoid arthritis among patients with arthralgia: A population-based study within two university cities of Sweden., PMID:29174794
BIRC5 is a novel target of peroxisome proliferator‑activated receptor γ in brain microvascular endothelium cells during cerebral ischemia., PMID:29039513
Evaluation of serum autoantibodies against tumor-associated antigens as biomarkers in lung cancer., PMID:29022480
Iodoacetyl-functionalized pullulan: A supplemental enhancer for single-domain antibody-polyclonal antibody sandwich enzyme-linked immunosorbent assay for detection of survivin., PMID:28974337
Autoimmune disease mouse model exhibits pulmonary arterial hypertension., PMID:28926602
The Prevalence of Cancer-Associated Autoantibodies in Patients with Gastric Cancer and Progressive Grades of Premalignant Lesions., PMID:28768706
Serum interleukin-6 and survivin levels predict clinical response to etanercept treatment in patients with established rheumatoid arthritis., PMID:28657833
Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)., PMID:28424988
Predictive value of p63, ki-67, and survivin expression in oral leukoplakia: A tissue microarray study., PMID:28346726
Clinical impact of serum survivin positivity and tissue expression of EBV-encoded RNA in diffuse large B-cell lymphoma patients treated with rituximab-CHOP., PMID:28099151
For research use only. Not for human or drug use.
