Catalog No.
RHE98201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
G0/G1 switch regulatory protein 3, G0S3, Protein fosB, GOSB, Oncogene FOSB, Activator protein 1, FOSB
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P53539
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1C07
Single-cell transcriptomic analysis reveals AP-1 downregulation remodels bone marrow environment and contributes to osteopenia in ovariectomized mice., PMID:40213116
Inhibitors of oncogenic Kras specifically prime CTLA4 blockade to transcriptionally reprogram Tregs and overcome resistance to suppress pancreas cancer., PMID:40093186
FOS+ Macrophages Promote Chronic Rejection of Cardiac Transplantation., PMID:39223812
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer., PMID:37692516
AP-1 Transcription Factor Complex Members FOSB and FOS are Linked With CNS Infiltration and Inferior Prognosis in Childhood T-ALL., PMID:37670804
Computational approaches for discovering significant microRNAs, microRNA-mRNA regulatory pathways, and therapeutic protein targets in endometrial cancer., PMID:36704357
Immunohistochemistry for FOSB and FOS is a Useful Ancillary Tool in the Diagnosis of Epithelioid Hemangioma but There are Pitfalls in Interpretation Including Expression in Other Vascular Lesions., PMID:35635207
The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma., PMID:34076685
Diagnostic Immunohistochemistry of Soft Tissue and Bone Tumors: An Update on Biomarkers That Correlate with Molecular Alterations., PMID:33921435
FosB recruits KAT5 to potentiate the growth and metastasis of papillary thyroid cancer in a DPP4-dependent manner., PMID:32891613
c-Fos and FosB/ΔFosB colocalizations in selected forebrain structures after olanzapine, amisulpride, aripiprazole, and quetiapine single administration in rats preconditioned by two different mild stressors sequences., PMID:32597143
Clinicopathologic study of 6 cases of epithelioid osteoblastoma of the jaws with immunoexpression analysis of FOS and FOSB., PMID:32482537
Epithelioid hemangioma of bone: A unique case with multifocal metachronous bone lesions., PMID:31708630
Pseudomyogenic hemangioendothelioma of bone treated with denosumab: a case report., PMID:31481040
Multiple Eruptive Epithelioid Hemangiomas: A Subset of Cutaneous Cellular Epithelioid Hemangioma With Expression of FOS-B., PMID:29266025
Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(S)-hydroxyeicosatetraenoic acid-induced monocyte trafficking., PMID:28724635
Region-specific increases in FosB/ΔFosB immunoreactivity in the rat brain in response to chronic sleep restriction., PMID:28089853
Progressive Seizure Aggravation in the Repeated 6-Hz Corneal Stimulation Model Is Accompanied by Marked Increase in Hippocampal p-ERK1/2 Immunoreactivity in Neurons., PMID:28018175
FOSB is a Useful Diagnostic Marker for Pseudomyogenic Hemangioendothelioma., PMID:28009608
Repeated asenapine treatment does not participate in the mild stress induced FosB/ΔFosB expression in the rat hypothalamic paraventricular nucleus neurons., PMID:27756486
In utero exposure to diesel exhaust particles induces anxiogenic effects on male offspring via chronic activation of serotonergic neuron in dorsal raphe nucleus., PMID:27665768
Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model., PMID:27340921
Response of colonic motility to dopaminergic stimulation is subverted in rats with nigrostriatal lesion: relevance to gastrointestinal dysfunctions in Parkinson's disease., PMID:26433214
Extension of the germinal center stage of B cell development promotes autoantibodies in BXD2 mice., PMID:23818250
Parathyroid hormone (1-34) counteracts the suppression of interleukin-11 expression by glucocorticoid in murine osteoblasts: a possible mechanism for stimulating osteoblast differentiation against glucocorticoid excess., PMID:23397032
Novel pathways in the pathobiology of human abdominal aortic aneurysms., PMID:22797469
Comparison of ΔFosB immunoreactivity induced by vagal nerve stimulation with that caused by pharmacologically diverse antidepressants., PMID:22286499
Imidazoline receptor antisera-selected/Nischarin regulates the effect of agmatine on the development of morphine dependence., PMID:21967557
Quantitative mapping of cocaine-induced ΔFosB expression in the striatum of male and female rats., PMID:21747956
FACS identifies unique cocaine-induced gene regulation in selectively activated adult striatal neurons., PMID:21411666
[Preparation and application of goat deltafosB gene expression product antibody]., PMID:21387834
Combined fluorescent in situ hybridization and immunofluorescence: limiting factors and a substitution strategy for slide-mounted tissue sections., PMID:21276820
Putaminal upregulation of FosB/ΔFosB-like immunoreactivity in Parkinson's disease patients with dyskinesia., PMID:23933656
ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward., PMID:20618447
Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and -3 expression and secretion via NF-kappaB- and Activator Protein-1-dependent monocyte networks., PMID:20483790
Mechanical stress induces Interleukin-11 expression to stimulate osteoblast differentiation., PMID:19665600
MCRS2 represses the transactivation activities of Nrf1., PMID:19187526
Recurrent hypoglycemia alters hypothalamic expression of the regulatory proteins FosB and synaptophysin., PMID:18753263
Immunohistochemical analysis of possible chemoresistance markers identified by micro-arrays on serous ovarian carcinomas., PMID:18500265
Ectopic expression of delta FBJ murine osteosarcoma viral oncogene homolog B mediates transdifferentiation of adipose-like spheroids into osteo-like microtissues., PMID:18491952
IL-4-induced Stat6 activities affect apoptosis and gene expression in breast cancer cells., PMID:18342537
B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element., PMID:18048365
The mitogen-activated protein kinase p38 regulates activator protein 1 by direct phosphorylation of c-Jun., PMID:17689131
Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors., PMID:17662258
Type 1 sphingosine 1-phosphate G protein-coupled receptor (S1P1) mediation of enhanced IL-4 generation by CD4 T cells from S1P1 transgenic mice., PMID:17404269
Differential effects of water deprivation and rehydration on Fos and FosB/DeltaFosB staining in the rat brainstem., PMID:17027755
A splice variant of CD99 increases motility and MMP-9 expression of human breast cancer cells through the AKT-, ERK-, and JNK-dependent AP-1 activation signaling pathways., PMID:16984917
The transcription factor DeltaFosB is recruited by inflammatory pain., PMID:16787404
Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas., PMID:16401477
CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum., PMID:16380431