Catalog No.
RHH13402
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Beta ig, Beta ig h3, Beta ig-h3, BGH3_HUMAN, Big h3, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, Kerato epithelin, Kerato-epithelin, LCD1, TGFBI
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q15582
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1B27
Proteolytic degradation of Beta-Ig H3 (βigH3/TGFBI) can be quantified non-invasively in serum and predicts prognosis in patients with advanced pancreatic ductal adenocarcinoma., PMID:40394523
SYT7 (synaptotagmin 7) promotes cervical squamous cell carcinoma., PMID:38314285
Significance of Lipopolysaccharides in Gastric Cancer and Their Potential as a Biomarker for Nivolumab Sensitivity., PMID:37511547
Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression., PMID:36325910
Proteomic analysis of peritoneal fluid identified COMP and TGFBI as new candidate biomarkers for endometriosis., PMID:34686725
TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer., PMID:34561272
Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis., PMID:33408771
Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia., PMID:32937590
Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C., PMID:32312959
The expression of cytokines in aqueous humor of high myopic patients with cataracts., PMID:32180680
ASO Author Reflections: High Stromal TGFBI is a Useful Predictive Marker for Nivolumab in Non-small Cell Lung Cancer., PMID:31696394
TGFBI Protein Is Increased in the Urine of Patients with High-Grade Urothelial Carcinomas, and Promotes Cell Proliferation and Migration., PMID:31514337
Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer., PMID:31277676
Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer., PMID:30415234
Biologic Response of Colorectal Cancer Xenograft Tumors to Sequential Treatment with Panitumumab and Bevacizumab., PMID:29802988
Lithium chloride (LiCl) induced autophagy and downregulated expression of transforming growth factor β-induced protein (TGFBI) in granular corneal dystrophy., PMID:29679546
Macrophage TGF-β1 and the Proapoptotic Extracellular Matrix Protein BIGH3 Induce Renal Cell Apoptosis in Prediabetic and Diabetic Conditions., PMID:28149671
TGFβ induces BIGH3 expression and human retinal pericyte apoptosis: a novel pathway of diabetic retinopathy., PMID:27564721
Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium., PMID:27143554
Tgfbi/Bigh3 silencing activates ERK in mouse retina., PMID:26387839
Absence of Vitamin K-Dependent γ-Carboxylation in Human Periostin Extracted from Fibrotic Lung or Secreted from a Cell Line Engineered to Optimize γ-Carboxylation., PMID:26273833
Inhibitory Effect of Tranilast on Transforming Growth Factor-Beta-Induced Protein in Granular Corneal Dystrophy Type 2 Corneal Fibroblasts., PMID:26020822
TGFBIp regulates differentiation of EPC (CD133(+) C-kit(+) Lin(-) cells) to EC through activation of the Notch signaling pathway., PMID:25786978
Inhibition of TGFBIp expression reduces lymphangiogenesis and tumor metastasis., PMID:25772247
BIGH3 protein and macrophages in retinal endothelial cell apoptosis., PMID:25378215
Spheroidal degeneration in H626R TGFBI variant lattice dystrophy: a multimodality analysis., PMID:24831201
Acquisition of useful sero-diagnostic autoantibodies using the same patients'sera and tumor tissues., PMID:24759181
ALK1 heterozygosity increases extracellular matrix protein expression, proliferation and migration in fibroblasts., PMID:24594380
Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor., PMID:24508728
Reproducibility of graft preparations in Descemet's membrane endothelial keratoplasty., PMID:23870299
Organized proteomic heterogeneity in colorectal cancer liver metastases and implications for therapies., PMID:23832580
Multiple FAS1 domains and the RGD motif of TGFBI act cooperatively to bind αvβ3 integrin, leading to anti-angiogenic and anti-tumor effects., PMID:23792174
A unique TGFBI protein in granular corneal dystrophy types 1 and 2., PMID:22746317
Investigation of the influence of Arg555Trp and Thr538Pro TGFBI mutations on C-terminal cleavage and cell endoplasmic reticulum stress., PMID:22605926
Lysophosphatidic acid activates TGFBIp expression in human corneal fibroblasts through a TGF-β1-dependent pathway., PMID:22374302
Unique TGFBI protein in lattice corneal dystrophy., PMID:21948648
Heavy-chain amyloidosis in TGFBI-negative and gelsolin-negative atypical lattice corneal dystrophy., PMID:21743312
βig-h3 regulates store-operated Ca2+ entry and promotes the invasion of human hepatocellular carcinoma cells., PMID:21395558
TL1A induces the expression of TGF-β-inducible gene h3 (βig-h3) through PKC, PI3K, and ERK in THP-1 cells., PMID:20863486
Granular and lattice deposits in corneal dystrophy caused by R124C mutation of TGFBIp., PMID:20697279
High glucose-induced apoptosis in bovine retinal pericytes is associated with transforming growth factor beta and betaIG-H3: betaIG-H3 induces apoptosis in retinal pericytes by releasing Arg-Gly-Asp peptides., PMID:20584023
TGFBI expression is associated with a better response to chemotherapy in NSCLC., PMID:20509890
Proteome analysis of human aqueous humor., PMID:20463327
Denaturation and solvent effect on the conformation and fibril formation of TGFBIp., PMID:20011632
Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease., PMID:19740775
C-terminal fragment of transforming growth factor beta-induced protein (TGFBIp) is required for apoptosis in human osteosarcoma cells., PMID:19505574
Invariant natural killer T cells and TGF-beta attenuate anti-GBM glomerulonephritis., PMID:19470687
Keratoconus associated with corneal stromal amyloid deposition containing TGFBIp., PMID:19421032
Inhibition of human scleral fibroblast cell attachment to collagen type I by TGFBIp., PMID:19387070
A corneal dystrophy associated with transforming growth factor beta-induced Gly623Asp mutation an amyloidogenic phenotype., PMID:19019446
For research use only. Not for human or drug use.
