Catalog No.
YHC15901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala18-Trp212
Predicted molecular weight
24.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05305
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Endothelin-1, EDN1, PPET1, ET-1, Preproendothelin-1,Endothelin1
Mechanism of Huoshan large-leaf yellow tea in treatment of diabetic cognitive dysfunction based on bioinformatics and network pharmacology., PMID:40505484
SK4 potentially modulates the alternative splicing profile associated with papillary thyroid cancer development in BHT101 cells., PMID:40452939
Environmental Aromatic Amine Induces Pulmonary Arterial Hypertension Associated With Estrogen Signaling and Serpine1., PMID:40344275
Transcriptome Analysis Reveals Possible Antitumor Mechanism of Intracellular Polysaccharide From Phaeodactylum tricornutum on Cervical Cancer HeLa Cells., PMID:40251892
Crosstalk Between Gastric Cancer and Adjacent Mucosa Reveals EDN1-EDNRA-Mediated Regulation of Cancer Stemness and Immunomodulation Networks., PMID:40245183
The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development., PMID:40171762
CD133+CD24+ Renal Tubular Progenitor Cells Drive Hypoxic Injury Recovery via Hypoxia-Inducible Factor-1A and Epidermal Growth Factor Receptor Expression., PMID:40141116
Ferulic acid in Chaihu Shugan San modulates depression-like behavior, endothelial and gastrointestinal dysfunction in rats via the Ghrl-Edn1/Mecp2/P-mTOR/VEGFA pathway: A multi-omics study., PMID:40127829
EDN1 and NTF3 in keloid pathogenesis: computational and experimental evidence as novel diagnostic biomarkers for fibrosis and inflammation., PMID:40051702
EDN1 facilitates cisplatin resistance of non-small cell lung cancer cells by regulating the TNF signaling pathway., PMID:40025550
The Impact of Mutant EDNRB on the Two-End Black Coat Color Phenotype in Chinese Local Pigs., PMID:40002960
The extracellular matrix protein type I collagen and fibronectin are regulated by β-arrestin-1/endothelin axis in human ovarian fibroblasts., PMID:39985042
Identification of biomarkers associated with macrophage polarization in diabetic cardiomyopathy based on bioinformatics and machine learning approaches., PMID:39914590
Key Genes and Biological Pathways in Pulmonary Arterial Hypertension Related to Endoplasmic Reticulum Stress Identified by Bioinformatics., PMID:39907642
Association of endothelial nitric oxide synthase (NOS3) rs2070744 variant with advanced retinopathy of prematurity: a case-control study and meta-analysis., PMID:39747280
Twist1 Acts Upstream of the Dlx5-Hand2 Pathway to Pattern the Mammalian Jaw., PMID:39707586
Biomimetic astrocyte cell membrane-fused nanovesicles for protecting neurovascular units in hypoxic ischemic encephalopathy., PMID:39695691
Identification of circRNA-miRNA-mRNA networks to explore underlying mechanism in lung cancer., PMID:39676897
Role of immune-related endoplasmic reticulum stress genes in sepsis-induced cardiomyopathy: Novel insights from bioinformatics analysis., PMID:39671358
Whole transcriptome sequencing identifies key lncRNAs, circRNAs and miRNAs in sepsis-associated acute lung injury., PMID:39587404
Genes related to microglia polarization and immune infiltration in Alzheimer's Disease., PMID:39390284
The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development., PMID:39345358
Exercise-Induced Shear Stress Drives mRNA Translation In Vitro., PMID:39329941
VEPTP inhibition with an extracellular domain targeting antibody did not restore albuminuria in a mouse model of diabetic kidney disease., PMID:39324545
Identification of dilated cardiomyopathy-linked key genes by bioinformatics methods and evaluating the impact of tannic acid and monosodium glutamate in rats., PMID:39318238
GCN2 kinase activation mediates pulmonary vascular remodeling and pulmonary arterial hypertension., PMID:39316438
Identification of key genes and pathways involved in T-DM1-resistance in OE-19 esophageal cancer cells through bioinformatics analysis., PMID:39309859
Exploring the therapeutic targets of stevioside in management of type 2 diabetes by network pharmacology and in-silico approach., PMID:39217825
Zibotentan in Microvascular Angina: A Randomized, Placebo-Controlled, Crossover Trial., PMID:39217504
L-ascorbate Alleviates Chronic Obstructive Pulmonary Disease through the EGF/PI3K/AKT Signaling Axis., PMID:39192652
Angelica sinensis polysaccharide facilitates chondrogenic differentiation of adipose-derived stem cells via MDK-PI3K/AKT signaling cascade., PMID:39191028
Network pharmacology-based exploration of molecular mechanisms underlying therapeutic effects of Jianpi Huatan Quyu recipe on chronic heart failure with spleen Qi deficiency syndrome., PMID:39086892
Transcriptomic Hallmarks of Hypoxic-Ischemic Brain Injury: Insights from an in Vitro Model., PMID:39082286
Genetic Polymorphisms in Cardiovascular Disease: Effects Across Three Generations Exposed to Radiation from the Semipalatinsk Nuclear Test Site., PMID:39030318
Integrative analysis of bulk and single-cell RNA sequencing reveals the gene expression profile and the critical signaling pathways of type II CPAM., PMID:39026356
Expression profiling and function analysis identified new genes regulating cumulus expansion and cumulus cell apoptosis in mouse oocytes., PMID:38949488
Identification of exosomal microRNAs and related hub genes associated with imatinib resistance in chronic myeloid leukemia., PMID:38916832
Comprehensive analysis of the endothelin system in the kidneys of mice, rats, and humans., PMID:38904098
Microarray analysis demonstrates up-regulation of the endothelin-1 gene with compensatory down-regulation of the ETA receptor gene in human portal vein., PMID:38860875
Endotype-driven Co-module mechanisms of danhong injection in the Co-treatment of cardiovascular and cerebrovascular diseases: A modular-based drug and disease integrated analysis., PMID:38705429
Study on the Mechanism of Competing Endogenous Network of 'Scutellaria barbata D.Don-Houttuynia cordata- Radix Scutellariae' in the Treatment of NSCLC based on Bioinformatics, Molecular Dynamics and Experimental Verification., PMID:38685811
Single-cell RNA sequencing reveals cellular and molecular landscape of fetal cystic hygroma., PMID:38650036
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro., PMID:38602103
Transfection of hypoxia-inducible factor-1α mRNA upregulates the expression of genes encoding angiogenic growth factors., PMID:38509125
HIF-1A as a prognostic biomarker related to invasion, migration and immunosuppression of cervical cancer., PMID:38298716
Enhanced quality of hESC-derived melanocytes through modified concentration of endothelin-1., PMID:38284190
Osteopontin interacts with dendritic cells and macrophages in pulp inflammation: Comprehensive transcriptomic analysis and laboratory investigations., PMID:38279773
Pharmacogenomics of intravenous immunoglobulin response in Kawasaki disease., PMID:38259468
Role of HIF-1α in hypercoagulable state of COPD in rats., PMID:38253248
Screening the critical protein subnetwork to delineate potential mechanisms and protective agents associated with arsenic-induced cutaneous squamous cell carcinoma: A toxicogenomic study., PMID:38219847
For research use only. Not for human or drug use.
