Catalog No.
RHE62401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Paired box protein Pax-1, PAX-1, PAXI, paxillin, paxillin alpha, Paxillin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P49023
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1B11
CXCL5 impedes CD8+ T cell immunity by upregulating PD-L1 expression in lung cancer via PXN/AKT signaling phosphorylation and neutrophil chemotaxis., PMID:39034411
Targeted serum proteome profiling reveals nicotinamide adenine dinucleotide phosphate (NADPH)-related biomarkers to discriminate linear IgA bullous disorder from dermatitis herpetiformis., PMID:38908771
Phosphatidylinositol 4-Kinase III Alpha Governs Cytoskeletal Organization for Invasiveness of Liver Cancer Cells., PMID:38636680
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking NaV 1.5-mediated EMT and FAK/Paxillin signaling pathway., PMID:33280262
Immunogenicity and safety of an adjuvanted inactivated polio vaccine, IPV-Al, following vaccination in children at 2, 4, 6 and at 15-18 months., PMID:32273184
Immunogenicity and safety of an adjuvanted inactivated polio vaccine, IPV-Al, compared to standard IPV: A phase 3 observer-blinded, randomised, controlled trial in infants vaccinated at 6, 10, 14 weeks and 9 months of age., PMID:31703934
Optic Nerve Head Astrocytes Display Axon-Dependent and -Independent Reactivity in Response to Acutely Elevated Intraocular Pressure., PMID:30665231
Imatinib Alters Agonists-mediated Cytoskeletal Biomechanics in Lung Endothelium., PMID:29075042
Heterogeneous Cell Types in Single-cell-derived Clones of MCF7 and MDA-MB-231 Cells., PMID:28476800
Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways., PMID:28423510
Suppression of IL-8-Src signalling axis by 17β-estradiol inhibits human mesenchymal stem cells-mediated gastric cancer invasion., PMID:26945908
Paxillin is positively correlated with the clinicopathological factors of colorectal cancer, and knockdown of Paxillin improves sensitivity to cetuximab in colorectal cancer cells., PMID:26530439
Concerted modulation of paxillin dynamics at focal adhesions by Deleted in Liver Cancer-1 and focal adhesion kinase during early cell spreading., PMID:25448629
Paxillin and focal adhesion kinase colocalise in human skeletal muscle and its associated microvasculature., PMID:24671495
17β-estradiol inhibits mesenchymal stem cells-induced human AGS gastric cancer cell mobility via suppression of CCL5- Src/Cas/Paxillin signaling pathway., PMID:24396281
Antitumour effects of Yangzheng Xiaoji in human osteosarcoma: the pivotal role of focal adhesion kinase signalling., PMID:23828123
Dual inhibition of αV integrins and Src kinase activity as a combination therapy strategy for colorectal cancer., PMID:23275294
Homocysteine induces serum amyloid A3 in osteoblasts via unlocking RGD-motifs in collagen., PMID:23085993
Monitoring the cytoskeletal EGF response in live gastric carcinoma cells., PMID:23028903
Cell dynamics in cervical loop epithelium during transition from crown to root: implications for Hertwig's epithelial root sheath formation., PMID:22973989
Antibody Microarray Analysis of Signaling Networks Regulated by Cxcl13 and Cxcr5 in Prostate Cancer., PMID:24009409
Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion., PMID:22139838
Laminin regulates mouse embryonic stem cell migration: involvement of Epac1/Rap1 and Rac1/cdc42., PMID:20089929
Glomerular proteins related to slit diaphragm and matrix adhesion in the foot processes are highly tyrosine phosphorylated in the normal rat kidney., PMID:20067908
Neutrophil granulocytes promote the migratory activity of MDA-MB-468 human breast carcinoma cells via ICAM-1., PMID:19747913
Reorganization of the integrin alpha2 subunit controls cell adhesion and cancer cell invasion in prostate cancer., PMID:19424590
Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells., PMID:18332220
Paxillin localisation in osteocytes--is it determined by the direction of loading?, PMID:18187040
Role of JNK-dependent serine phosphorylation of paxillin in migration of corneal epithelial cells during wound closure., PMID:18172084
Papilloma protein E6 abrogates shear stress-dependent survival in human endothelial cells: evidence for specialized functions of paxillin., PMID:16624261
Activation of the lutropin/choriogonadotropin receptor in MA-10 cells leads to the tyrosine phosphorylation of the focal adhesion kinase by a pathway that involves Src family kinases., PMID:16293639
Adhesion-dependent activation of CaMKII and regulation of ERK activation in vascular smooth muscle., PMID:15944210
Uni-axial stretching regulates intracellular localization of Hic-5 expressed in smooth-muscle cells in vivo., PMID:15713747
A streptococcal collagen-like protein interacts with the alpha2beta1 integrin and induces intracellular signaling., PMID:15647274
The lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1., PMID:15590642
Measurement of protein tyrosine phosphorylation in cell adhesion., PMID:15576919
Expression of the urokinase receptor regulates focal adhesion assembly and cell migration in adenoid cystic carcinoma cells., PMID:15521066
alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor., PMID:15466886
Vitamin D3 modulated gene expression patterns in human primary normal and cancer prostate cells., PMID:15368355
HLA class I signal transduction is dependent on Rho GTPase and ROK., PMID:15351723
Phosphorylation of paxillin tyrosines 31 and 118 controls polarization and motility of lymphoid cells and is PMA-sensitive., PMID:15252114
Paxillin selectively associates with constitutive and chemoattractant-induced high-affinity alpha4beta1 integrins: implications for integrin signaling., PMID:15242880
Protein kinase A inhibits lysophosphatidic acid induction of serum response factor via alterations in the actin cytoskeleton., PMID:15240009
Ligand stimulation of CD155alpha inhibits cell adhesion and enhances cell migration in fibroblasts., PMID:15194502
Differential regulation of focal adhesion kinase and paxillin phosphorylation by the small GTP-binding protein Rho in human corneal epithelial cells., PMID:15175910
Extracellular myocilin affects activity of human trabecular meshwork cells., PMID:15137056
LIM kinase 1, a key regulator of actin dynamics, is widely expressed in embryonic and adult tissues., PMID:15023529
Immunohistochemical comparison of vascular and sinusoidal adherens junctions in cavernosal endothelium., PMID:14751392
The role of alpha(5)beta(1)-integrin in the IGF-I-induced migration of extravillous trophoblast cells during the process of implantation., PMID:14742693
Ionizing radiation modules of the expression and tyrosine phosphorylation of the focal adhesion-associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cells in vitro., PMID:14703945
For research use only. Not for human or drug use.
