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Recombinant Human IL6 Protein, C-His

Catalog #:   EHC15802 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: Mammalian Cells
Accession: P05231
Protein length: Val30-Met212
Overview

Catalog No.

EHC15802

Expression system

Mammalian Cells

Species

Homo sapiens (Human)

Protein length

Val30-Met212

Predicted molecular weight

16.74 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P05231

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Hybridoma growth factor, BSF-2, IFN-beta-2, CDF, IL6, Interleukin-6, IL-6, B-cell stimulatory factor 2, Interferon beta-2, IFNB2, CTL differentiation factor

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human IL6
  • Bioactivity
    Detects Ziltivekimab in indirect ELISAs.
  • Bioactivity
    Detects Sirukumab in indirect ELISAs.
  • Bioactivity
    Detects Olokizumab in indirect ELISAs.
References

Impact of elective surgery on tumor necrosis factor-α, interleukin-6 and quality of life in uncomplicated diverticular disease., PMID:40491034

Involvement of IL-6/JAK/STAT3/SOCS3, SIRT1, and Cytoglobin Signaling in Diacerein Protective Effect against Intestinal Injury Induced by Methotrexate., PMID:40488252

Gallic acid suppresses esophageal squamous cell carcinoma progression and enhances cisplatin chemosensitivity through IL-6/STAT3/Notch pathway., PMID:40486873

Family history, inflammation, and cerebellum in major depression: a combined VBM and dynamic functional connectivity study., PMID:40467567

Associations among IL-6 Signaling Molecules in Treg Populations in Patients with Relapsing-Remitting Multiple Sclerosis., PMID:40464469

RNase 7 and Th cytokines synergistically increase the secretion of interleukin-6 from keratinocytes., PMID:40461723

Hsa-miR-21-5p is induced by interleukin-6 and affects multiple pathogenic factors associated with fibroblast-like synoviocytes in rheumatoid arthritis., PMID:40461641

Expression of salivary hepcidin and its inducer, interleukin 6 as well as type I interferons are significantly elevated in infants with poor oral rotavirus vaccine take in South Africa., PMID:40453081

Alternative Combinations of IL17A Polymorphic Variants with the Variants of TNF, IL1B, IL6, and IL8 Proinflammatory Cytokines Genes in Uterine Leiomyoma., PMID:40448881

Comparative Effectiveness of TNF-α and IL-6 Inhibitors on Bone Health Outcomes and Mortality in Rheumatoid Arthritis Patients: A Retrospective Cohort Study., PMID:40443049

Evaluation of 'Cytorisk Index' (IL-6*survivin/IL-4 ratio) as a predictor of tumour aggression in breast cancer., PMID:40435911

IL-6 is a prognostic biomarker in patients with advanced esophageal squamous cell carcinoma received with PD-1 inhibitors., PMID:40433391

IL-10 and IL-6/IL-10 as predictive biomarkers for treatment response in non-infectious uveitis., PMID:40433375

Association of Vitamin D Supplementation with Glutathione Peroxidase (GPx) Activity, Interleukine-6 (IL-6) Levels, and Anxiety and Depression Scores in Patients with Post-COVID-19 Condition., PMID:40429727

Effect of Continuous Intraoperative Dexmedetomidine on Interleukin-6 and Other Inflammatory Markers After Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial., PMID:40428745

Association of CETP, APOA5, IL6, and PON1 Gene Variants with Dyslipidemia and Cardiovascular Risk in a Population from Cauca Department, Colombia., PMID:40428368

The Association Between Myokines, Inflammation, and Nutritional Status in Patients with Multiple Sclerosis., PMID:40427596

Serum IL-6 and PTX3 predict severe outcome from COVID-19 in ambulatory subjects: Impact for future therapeutic decisions., PMID:40424310

C-reactive protein conformations and their association with the IL-1β/IL-6 pathway in ocular inflammatory conditions., PMID:40421028

Serum Cytokine 6, 10 and α-Tumour Necrosis Factor Levels in Alzheimer's Disease Subjects Treated with Donepezil Plus Vitamin B12., PMID:40408576

IL-6-induced long noncoding RNA MIR3142HG promotes tumorigenesis by interacting with thioredoxin-1 and STAT3 in human colorectal cancer., PMID:40405062

PSME2 promotes malignant progression through autophagy modulation via IL-6/STAT3 signaling pathway in esophageal squamous cell carcinoma., PMID:40404117

Does the IL-6/KL-6 ratio distinguish different phenotypes in COVID-19 Acute Respiratory Distress Syndrome? An observational study stemmed from prospectively derived clinical, biological, and computed tomographic data., PMID:40397955

Diagnostic value of EOS count and serum VEGF in bronchial asthma and their correlation with inflammatory factors and lung function indicators., PMID:40389917

Polymorphisms in rs2069845 are associated with IL-6 and soluble IL-6 receptor levels during total joint replacement., PMID:40373041

CD28+ CD45RA- CD8br AC mediated the effects of Interleukin- 6 on Alzheimer's disease: A Mendelian Randomization Study., PMID:40369481

Interleukin-6 in Anthracycline-Related Cardiac Dysfunction: A Comparison with Myeloperoxidase and TNF-Alpha., PMID:40362309

Study of some biological markers in cord blood of preterm and term infants and their association with neonatal sepsis., PMID:40353384

Intrapleural dual blockade of IL-6 and PD-L1 reprograms CAF dynamics and the tumor microenvironment in lung cancer-associated malignant pleural effusion., PMID:40349069

Role of inflammation in depressive and anxiety disorders, affect, and cognition: genetic and non-genetic findings in the lifelines cohort study., PMID:40348744

Association between frailty and inflammatory cytokines in patients with multiple sclerosis: a case-control study., PMID:40334398

Impact of pre-transplant serum levels of activin A, activin B, IGF-1 and IL-6 on transplant outcomes and survival in patients with multiple myeloma: a prospective study., PMID:40322823

Prognostic impact of serum interleukin-6 and 17 level in patients with bladder cancer: a systematic review and meta-analysis., PMID:40321822

Interleukin-6 modifies Lipoprotein(a) and oxidized phospholipids associated cardiovascular disease risk in a secondary prevention cohort., PMID:40318255

Analysis of serum levels of HIF-1α and IL-6 in patients with acute stanford type a aortic dissection., PMID:40307817

Immune-related biochemical markers and 20-year incidence of atherosclerotic cardiovascular disease: the ATTICA study (2002-2022)., PMID:40306152

Neutrophil Z Is a Novel Marker to Differentiate Disease Flares From Bacterial Infections in Febrile SLE Patients., PMID:40302194

Inflammatory and Antioxidant Status in Peri-Implant Health and Diseases: A Biochemical Analysis., PMID:40300144

Quantification of intra-amniotic inflammation in late preterm prelabour rupture of membranes., PMID:40295647

LoC-SERS detection platform based on targeted signal anchoring mechanism, high-sensitivity detection of protein biomarkers in precancerous lesions of gastric cancer., PMID:40280078

The interplay between cell-free DNA, hepcidin, and interleukin-6 in chronic kidney disease induced inflammation and progression to a hemodialysis dependent state., PMID:40272917

The role and clinical significance of myeloperoxidase (MPO) and TNF-α in prognostic evaluation of T-COPD., PMID:40269819

Investigating the relationship between the IL-17 rs2275913, IL-17 rs763780, and the IL-6 rs1800795 genotypes in HIV-positive patients with COVID-19., PMID:40268781

Role of IL-2, IL-6, and TNF-α as Potential Biomarkers in Ischemic Heart Disease: A Comparative Study of Patients with CAD and Non-CAD., PMID:40265387

Procalcitonin and interleukin- 6 in predicting prognosis of sepsis patients with cancer., PMID:40261444

Human IL-6-Producing B Cells Promote the Differentiation of Monocytes Toward an Anti-Inflammatory CD16⁺CD163⁺CD206⁺PD-L1⁺ Phenotype in Tuberculosis., PMID:40252014

Salivary Interleukin-6 and Interleukin-18 Levels and Their Association with Dental Health in Children with Idiopathic Nephrotic Syndrome., PMID:40243946

Reply to Saleh, C.; Budincevic, H. Interleukin-6, Tocilizumab and Atherosclerosis. Comment on "Gerasimova et al. Interleukin-6: Cardiovascular Aspects of Long-Term Cytokine Suppression in Patients with Rheumatoid Arthritis. Int. J. Mol. Sci. 2024, 25, 12425"., PMID:40243555

Interleukin-6, Tocilizumab and Atherosclerosis. Comment on Gerasimova et al. Interleukin-6: Cardiovascular Aspects of Long-Term Cytokine Suppression in Patients with Rheumatoid Arthritis. Int. J. Mol. Sci. 2024, 25, 12425., PMID:40243553

Cytokine response to resistance exercise in children with excess adiposity and Prader-Willi syndrome., PMID:40243109

Datasheet
$ 480
Product specifications
100 μg 480 1 mg 2880

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For research use only. Not for human or drug use.

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Recombinant Human IL6 Protein, C-His [EHC15802]
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