Catalog No.
RHA98601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
CAS, P120CAS, P120CTN, CTNND, p120, delta Catenin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O60716
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4 ℃ short term (1-2 weeks).
Store at -20 ℃ 12 months.
Store at -80 ℃ long term.
Clone ID
R1A20
Loss of p120ctn causes EGFR-targeted therapy resistance and failure., PMID:33112928
Differential expression of p120-catenin 1 and 3 isoforms in epithelial tissues., PMID:30643202
SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4., PMID:30584103
RORα2 requires LSD1 to enhance tumor progression in breast cancer., PMID:28931919
Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer., PMID:26067913
p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas., PMID:25523391
Diagnostic utility of E-cadherin and P120 catenin cocktail immunostain in distinguishing DCIS from LCIS., PMID:24966968
Glial cell-derived neurotrophic factor attenuates neuropathic pain in a mouse model of chronic constriction injury: possible involvement of E-cadherin/p120ctn signaling., PMID:24599758
Regulation of pre-fusion events: recruitment of M-cadherin to microrafts organized at fusion-competent sites of myogenic cells., PMID:23978243
Is expression of p120ctn in oral squamous cell carcinomas a prognostic factor?, PMID:23706919
Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability., PMID:23653363
TNF-α-mediated bronchial barrier disruption and regulation by src-family kinase activation., PMID:23632299
Association of Rho-associated protein kinase 1 with E-cadherin complexes is mediated by p120-catenin., PMID:22031287
Cyclic stretch induces alveolar epithelial barrier dysfunction via calpain-mediated degradation of p120-catenin., PMID:21571907
p120 regulates endothelial permeability independently of its NH2 terminus and Rho binding., PMID:20971762
p120ctn and P-cadherin but not E-cadherin regulate cell motility and invasion of DU145 prostate cancer cells., PMID:20668551
Downregulation of HDPR1 is associated with poor prognosis and affects expression levels of p120-catenin and beta-catenin in nonsmall cell lung cancer., PMID:20232357
p120-Catenin is required for mouse vascular development., PMID:20110533
Kaiso is expressed in lung cancer: its expression and localization is affected by p120ctn., PMID:19615783
Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell-cell adhesion., PMID:19421152
PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway., PMID:18950621
P120 catenin is associated with desmogleins when desmosomes are assembled in high-Ca2+ medium but not when disassembled in low-Ca2+ medium in DJM-1 cells., PMID:18578707
Effect of di-(2-ethylhexyl) phthalate on N-cadherin and catenin protein expression in rat testis., PMID:16678996
Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases., PMID:15833838
Disruption of cadherin/catenin expression, localization, and interactions during HgCl2-induced nephrotoxicity., PMID:15084754
Reduced expression and aberrant localization of p120catenin in human squamous cell carcinoma of the skin., PMID:15033192
Laminar shear stress differentially modulates gene expression of p120 catenin, Kaiso transcription factor, and vascular endothelial cadherin in human coronary artery endothelial cells., PMID:14699141
Glomerular crescents predominantly express cadherin-catenin complex in pauci-immune-type crescentic glomerulonephritis., PMID:12877733
N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane., PMID:12604612
Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis?, PMID:12533412
Glutamate-induced delta-catenin redistribution and dissociation from postsynaptic receptor complexes., PMID:12453475
Dynamic testicular adhesion junctions are immunologically unique. I. Localization of p120 catenin in rat testis., PMID:11906917
Evaluation of E-cadherin/catenin complex in primary and secondary glomerulonephritis., PMID:11877565
Decreased expression of catenins (alpha and beta), p120 CTN, and E-cadherin cell adhesion proteins and E-cadherin gene promoter methylation in prostatic adenocarcinomas., PMID:11753952
Tissue distribution and cell type-specific expression of p120ctn isoforms., PMID:11724896
Co-downregulation of cell adhesion proteins alpha- and beta-catenins, p120CTN, E-cadherin, and CD44 in prostatic adenocarcinomas., PMID:11521230
Changes in E-cadherin associated with cytoplasmic molecules in well and poorly differentiated endometrial cancer., PMID:11027430
The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin., PMID:10835420
N-cadherin-mediated adhesion and aberrant catenin expression in anaplastic thyroid-carcinoma cell lines., PMID:10521809
The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor., PMID:10207085
Expression of Src family kinases and their putative substrates in the human preosteoclastic cell line FLG 29.1., PMID:9844106
The expression of p120ctn protein in breast cancer is independent of alpha- and beta-catenin and E-cadherin., PMID:9422525
p120-catenin expression in human colorectal cancer., PMID:8895533
p120, a p120-related protein (p100), and the cadherin/catenin complex., PMID:7615637