Catalog No.
YHC13201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly300
Predicted molecular weight
36.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05108
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, CYP11A, Cholesterol desmolase, Cytochrome P450 11A1, CYP11A1, Cytochrome P450(scc)
Anti-androgenic and anti-proliferative properties of methanolic leaf extract of Allamanda cathartica Linn. in adult mouse testis: Evidences from in vivo and in silico studies., PMID:40482784
Reproductive toxicity of per- and polyfluoroalkyl substances., PMID:40473150
Drug repurposing reveals posaconazole as a CYP11A1 inhibitor enhancing anti-tumor immunity., PMID:40454094
Effects of Copper on Steroid Hormone Secretion, Steroidogenic Enzyme Expression, and Transcriptomic Profiles in Yak Ovarian Granulosa Cells., PMID:40431521
Cadmium-induced disruption of exosomal secretion and cellular pathways in leydig cells., PMID:40425944
1,25(OH)2D3 up-regulated mitochondrial dynamics and biogenesis to modulate steroidogenesis in the scent glands of muskrats (Ondatra zibethicus)., PMID:40398522
Combining ATAC-seq and RNA-seq reveals key genes for gonadal abnormalities in one-month-old XX-DSD pigs., PMID:40329180
Prenatal genistein exposure in rats affects pubertal onset and serum reproductive hormone levels in male offsprings via the hypothalamic-pituitary-gonadal axis., PMID:40320066
Expression and regulation of adrenomedullin 2 gene in ovarian follicles and its effect on follicular granulosa cells in chicken., PMID:40300324
Advances in Targeted Therapy for Metastatic Prostate Cancer., PMID:40299225
Bimodal genomic approach predicting Semaphorin 7A (SEMA7A) as prognostic biomarker in adrenocortical carcinoma., PMID:40291702
Molecular Mechanisms Contributing to the Impairment of Steroid Hormones, Sperm Characteristics, and Testicular Architecture in Male Rabbits After Chronic Exposure to Cadmium: Role of Gallic Acid and Selenium as Antioxidants., PMID:40278639
Consequences of vitamin D deficiency or overdosage on follicular development and steroidogenesis in Normo and hypo calcemic mouse models., PMID:40274992
Single cell resolution of neurosteroidogenesis in the murine brain: de novo biosynthesis., PMID:40261711
Electron transfer engineering of artificially designed cell factory for complete biosynthesis of steroids., PMID:40258825
Co-administration of atorvastatin with piperine induces reproductive toxicity in male Wistar rats through oxidative stress induction and downregulation of StAR, CYP11a1, 3βHSD and 17βHSD genes., PMID:40246250
Impact of Excess Activin A on the Lipids, Metabolites, and Steroids of Adult Mouse Reproductive Organs., PMID:40209098
Zingerone modulates the circulating steroids hormone levels and testicular steroidogenic markers expression in mice: An in vivo and in silico study., PMID:40189108
Prenatal bisphenol A exposure causes sperm quality and functional defects via Leydig cell impairment and meiosis arrest in mice offspring., PMID:40118943
Suppression of FOXO1 activity by SIRT1-mediated deacetylation weakening the intratumoral androgen autocrine function in glioblastoma., PMID:40075208
Genome-wide association analysis identified the involvement of MRPS22 in the regulation of Muscovy duck broodiness., PMID:40068571
Melamine-induced adrenal structural and functional alterations and the contribution of morin to the adrenal repair in Wistar rats., PMID:40056657
The vitamin D3 hormone, 1,25(OH)2D3, regulates fibroblast growth factor 23 (FGF23) production in human skin cells., PMID:40055144
Structural analysis and core promoter prediction of STAR gene and its regulatory mechanism of progesterone synthesis in bovine luteal cells., PMID:40044781
The proteomic landscape of trophoblasts unravels calcium-dependent syncytialization processes and beta-chorionic gonadotropin (ß-hCG) production., PMID:40038668
Elaidic acid induces testicular oxidative stress, inflammation, Wnt/β-catenin disruption and abnormalities in steroidogenesis, spermatogenesis and histo-architecture in Sprague Dawley rats., PMID:40032023
Pre-gestational restraint stress affects reproductive outcomes in adult rats by modulating ovarian and uterine function., PMID:40015659
Biological and therapeutic implications of sex hormone-related gene clustering in testicular cancer., PMID:40011822
Emerging per- and polyfluoroalkyl substance perfluoro-(3,5,7,9-tetraoxadecanoic) acid (PFO4DA) impairs steroidogenesis and spermatogenesis by suppressing StAR and CYP11A1 expression in mice., PMID:40009946
Impact of lisinopril on cisplatin-induced inflammation, oxidative stress, apoptosis, and impaired steroidogenesis in rat testis: involvement of Nrf2/Keap1/HO-1 and PPARγ signaling., PMID:40009171
Neddylation inhibition affects cell proliferation and steroidogenesis in sheep follicular granulosa cells., PMID:39986219
Mitotane activates ATF4/ATF3 axis triggering endoplasmic reticulum stress in adrenocortical carcinoma cells., PMID:39965324
HIF1α controls steroidogenesis under acute hypoxic stress., PMID:39948619
Prenatal exposure to an environmentally relevant phthalate mixture alters oxidative stress, apoptosis, cell cycle regulators, and steroidogenic factors in the ovaries of F1 mice., PMID:39947446
Bisphenol B restrains rat leydig cell function via H3K27me3/H3K9me3 histone modifications., PMID:39919587
Lactational high weight loss impairs follicular development by causing mitochondrial dysfunction of ovarian cells in sows and mitigated by butyrate supplement., PMID:39892609
Inhibition of FTO expression by thiodiphenol impairs Leydig cell maturation in pubertal male rats., PMID:39889475
Cholic acid inhibits ovarian steroid hormone synthesis and follicular development through farnesoid X receptor signaling in mice., PMID:39884637
Identification of Novel 58-5p and SREBF1 Interaction and Effects on Apoptosis of Ovine Ovarian Granulosa Cell., PMID:39859292
1,25(OH)₂D₃ regulates androgen synthesis via transcriptional control of steroidogenic enzymes and LHR in the scented glands of muskrats (Ondatra zibethicus)., PMID:39827922
In Utero Perfluorodecanoic Acid Exposure Causes Fetal Leydig Cell Dysfunction via Endoplasmic Reticulum Stress-Mediated Lipid Composition Alteration., PMID:39814558
18 kDa TSPO targeting drives polarized human microglia towards a protective and restorative neurosteroidome profile., PMID:39757281
Improvement of Late-Onset Hypogonadism Symptoms of Fermented Morinda citrifolia Extract in TM3 Leydig and TM4 Sertoli Cells., PMID:39683553
Human Cytochrome P450 Cancer-Related Metabolic Activities and Gene Polymorphisms: A Review., PMID:39682707
Cyclopiazonic acid suppresses the function of Leydig cells in prepubertal male rats by disrupting mitofusin 1-mediated mitochondrial function., PMID:39672039
Reversibility of polystyrene nanoplastics-induced disruption of testosterone biosynthesis in mice: The role of histone modifications., PMID:39662582
APN/AdipoRon regulates luteal steroidogenesis through AMPK/EZH2/H3K27me3 in goats., PMID:39647537
Evaluating ovarian follicles and their steroid hormone gene expression patterns in a high egg-producing research turkey line., PMID:39616679
Melatonin alleviates oxidative stress and inflammation of Leydig cells of Min pig through SIRT1 pathway., PMID:39613495
Localization and expression of C1QTNF6 in chicken follicles and its regulatory effect on follicular granulosa cells., PMID:39566174
For research use only. Not for human or drug use.
