Catalog No.
AMC12001
Biological activity
Measured by its ability to inhibit MCF-7 cells proliferation. The ED50 for this effect is <2 ng/mL. The specific activity of recombinant mouse IGF1 (Cat #: AMC12001) is > 5 x 10^5 IU/mg
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Gly33-Ala102
Nature
Recombinant
Endotoxin level
<1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8CAR0
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C, Drug Target
Dietary Inclusion Effects of Dried Mealworm, Hydrolyzed Mealworm, Fermented Poultry By-Product, and Hydrolyzed Fish Soluble Protein on Weaning Pigs' Performance, Fecal Score, and Blood Profiles., PMID:40508973
A human cytotrophoblast-villous endothelium-fetal organ multi-cell model and the impact on gene and protein expression in placenta cytotrophoblast, fetal hepatocytes and fetal kidney epithelial cells., PMID:40505174
Aromatic turmerone regulates the migration and autophagy of cutaneous squamous cell carcinoma cells through the Igf-1/Pi3k/Akt pathway., PMID:40501236
Impact of IGFBP-3 A-202C genetic variant on breast cancer susceptibility and serum biomarkers (IGFBP-3 and IGF-1) in Palestinian women., PMID:40493660
Targeting neurotrophic dysregulation in diabetic retinopathy: a novel therapeutic avenue., PMID:40488922
Exercise training benefits pancreatic islet by modulating the insulin-like growth factor 1/phosphatidylinositol 3-kinase/protein kinase B pathway., PMID:40487621
Bone, dentin and cementum differentially influence the differentiation of osteoclast-like cells., PMID:40473827
The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription., PMID:40470746
Goat milk oligosaccharides improve growth and gut microbiota composition in stunted mice., PMID:40467228
Alcohol, Anti-HIV Drugs, and/or Hippuric Acid Deteriorate Cellular Stresses in Senescent Hepatocytes and Aging Murine Liver., PMID:40463894
Impact of 16/8 time-restricted eating on body composition and lipolytic hormone regulation in female DanceSport dancers., PMID:40462558
Adipocyte/Tumor cell crosstalk via IGF-1/TXNIP axis promotes malignancy and endocrine resistance in breast cancer., PMID:40462107
Antisense oligonucleotide-mediated redirection of Igf1 alternative polyadenylation., PMID:40450413
Gestational fish oil supplementation in high-fat diet induces sex-specific myokine changes in weanling offspring., PMID:40459971
Effects of energy source on growth and body composition of Holstein calves fed only milk replacer or whole milk., PMID:40451581
Effects of the nuclear localization sequence and C-terminus of Parathyroid hormone-related protein on the growth Hormone-IGF-1 axis., PMID:40451546
Ghrelin relieves the reproductive damage of TiO2 NPs in young male rats via ROS/AMPK/mTOR signaling pathway., PMID:40451335
Chondroitin sulfate/hyaluronic acid/carboxymethylcellulose macroporous cryogels for controlled delivery of TGF-β1 and IGF-1 to induce chondrogenic differentiation of adipose-derived stem cells in cartilage tissue engineering., PMID:40449777
Triglycerides-Total Cholesterol-Body Weight Index, bone metabolism indicators and bone mineral density in Chinese children: a mediation analysis., PMID:40445364
Brain-acting hepatokines: its impact on energy balance and metabolism., PMID:40443802
Insulin- Like Growth Factor-1 as Brain-Body Connector., PMID:40442384
IGF-1 contributes to cardiovascular protection in obesity by upregulating Na+/K+-ATPase activity and modulating key signaling pathways in rats on a high-fat diet., PMID:40441487
QSOX2-Mediated Disulfide Bond Modification Enhances Tumor Stemness and Chemoresistance by Activating TSC2/mTOR/c-Myc Feedback Loop in Esophageal Squamous Cell Carcinoma., PMID:40433832
The Possible Role of Postnatal Biphasic Dysregulation of IGF-1 Tone in the Etiology of Idiopathic Autism Spectrum Disorder., PMID:40429628
Identification and Functional Validation of ACSL1 and FABP3 as Muscle-Related Genes Screened by Transcriptomics in Crossbred Duroc × Berkshire × Diannan Small-Eared Pigs., PMID:40428342
Genetic Insights into Severe Obesity: A Case Study of MC4R Variant Identification and Clinical Implications., PMID:40428329
Functional Equivalence of Insulin and IGF-1 in the In Vitro Culture of Chicken Primordial Germ Cells., PMID:40428303
The Characterization of Serum-Free Media on Human Mesenchymal Stem Cell Fibrochondrogenesis., PMID:40428164
Serum Concentrations of Insulin-like Growth Factor-1 (IGF-1), 26S Proteasome (26S PSM), and 3-Methylhistidine (3-MH) in Cats with Hypertrophic Cardiomyopathy., PMID:40427314
RNA sequencing and genome-wide association analysis reveal key genes responsible for different feather colors in Youjiang goose., PMID:40424883
Shared molecular mechanisms of bisphenol A and phthalates in endometriosis: A bioinformatics and molecular docking study., PMID:40424730
Mitigating Cadmium Toxicity: The Therapeutic Potential of Lactobacillus acidophilus Pro4 in Mice., PMID:40423875
Klotho protein: a multifaceted regulator in aging and cancer dynamics., PMID:40423846
Transcriptome Profiling of Trabecular Meshwork Progenitor Cells., PMID:40423739
Comparison of the clinical and prognostic characteristics of patients with different pathological types in acromegaly., PMID:40421250
Animal and Plant Protein Usual Intakes are Not Adversely Associated with All-Cause, Cardiovascular Disease- or Cancer-Related Mortality Risk: An NHANES III Analysis., PMID:40418846
Triptolide Ameliorates Collagen-Induced Arthritis and Bleomycin-Induced Pulmonary Fibrosis in Rats by Suppressing IGF1-Mediated Epithelial Mesenchymal Transition., PMID:40418457
Growth hormone regulates deiodinase type 2 and 3 expression via GATA., PMID:40413916
[Activation markers of the stress system in patients with type 1 diabetes during hypoglycemia]., PMID:40411329
Sub-chronic nanoplastic toxicity in Etroplus suratensis (Pisces, Cichilidae): Insights into tissue accumulation, stress and metabolic disruption., PMID:40409126
Mechanisms underlying obesity-malignancy connection: a systematic narrative review., PMID:40408050
Effect of Current and Former Anabolic-Androgenic Steroid Abuse on the Patellar Tendon., PMID:40407232
The role of insulin-like growth factor-1 in lactation., PMID:40404070
Efficacy, safety, and insulin-like growth factor I of weekly somapacitan in children with growth hormone deficiency: 3-year results from REAL4., PMID:40400262
Increased insulin-like growth factor-1 concentrations in paediatric suprasellar low-grade glioma: an international multicentre study., PMID:40400261
Stress exposure affects amyotrophic lateral sclerosis pathogenesis via PI3K/Akt and focal adhesion pathways: evidence from three experimental models., PMID:40399476
Genetic predictors of longevity and survival in cellular homeostasis genes: A case-control study., PMID:40398646
Fidaxomicin reduces collagen expression in intestinal fibroblasts via platelet-derived growth factor receptor beta and glycogen synthase kinase-3 beta inhibition., PMID:40398622
Fecal microbiota transplantation improves growth performance of chickens by increasing the intestinal Lactobacillus and glutamine., PMID:40398303
Borate-modified recombinant type XVII collagen microneedles loaded with IGF-1 for the treatment of androgenetic alopecia., PMID:40398062
For research use only. Not for human or drug use.
