Catalog No.
AMB74001
Biological activity
Measured in a cell proliferation assay using mouse helper T cells (D10.G4.1). The ED50 for this effect is 0.0125-0.05 ng/mL.
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Ser109-Ile266
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8BVZ5
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11,
Proteomic profiling reveals immunomodulatory role of IL-33 in ocular bacterial and fungal infections., PMID:40512033
Modeling Human Airway Epithelial Barrier Penetration Using Birch Bet v 1 and Alder Aln g 1 Pollen Allergens During Sensitization Process., PMID:40507979
Respiratory Syncytial Virus Infection Disrupts Airway Epithelial Barriers via IL-33/ST2/MyD88 Signaling Axis., PMID:40497542
Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710
The glycocalyx of Lacticaseibacillus paracasei NPB01 presents two different rhamnose-rich polysaccharides with non-equivalent immunomodulating activities., PMID:40484587
Effect of adaptive servo-ventilation on circulating biomarkers in patients with sleep apnoea after myocardial infarction: results of an ancillary analysis of the randomised TEAM-ASV I trial., PMID:40479758
Effect of EP395, a novel anti-inflammatory macrolide, in an inhaled lipopolysaccharide challenge model in healthy volunteers: a randomised controlled trial., PMID:40466859
A tryptophol-containing emulgel ameliorates imiquimod-induced mice psoriasis., PMID:40461662
Unveiling the Intricate Causal Nexus Between 91 Circulating Inflammatory Proteins and Perianal Abscess Through a Comprehensive Bidirectional Two-Sample Mendelian Randomization Analysis., PMID:40453734
Alleviation of dextran sulfate sodium (DSS)-induced colitis in mice through the antioxidative effects of muscone via the MyD88/p38 MAPK signalling pathway., PMID:40452925
Small Proline-Rich Protein 2A Drives Epithelial Remodeling in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps via SAA2 Upregulation., PMID:40447198
Potential Inflammatory Mediators in Pericardial Fluids of Patients With Coronary Artery Diseases and Their Association With Plasma Biomarkers., PMID:40437664
In Silico Analysis of Novel circRNA-miRNA-mRNA Axis in BRAFV600E Melanoma: Implications for Primary to Metastasis Transformation and TIME Modulation., PMID:40436810
[Not Available]., PMID:40433883
Codium fragile Extract Ameliorates Respiratory Function by Controlling Allergic Inflammation in Ovalbumin-Induced Bronchial Disorders in Mice., PMID:40422811
Immune, metabolic, anatomical, and functional features of people after successful tuberculosis treatment: an exploratory analysis., PMID:40419526
Enhancing the Affinity of a Novel Selective scFv for Soluble ST2 through Computational Design., PMID:40417773
Targeting of the IL-33/Wnt axis restricts breast cancer stemness and metastasis., PMID:40414980
Metformin alleviates inflammatory responses in acute allergic asthma by inhibiting ILC2s function., PMID:40398255
Differential activation of monocytes and PMNs in orofacial granulomatosis patients induced by bacterial and non-bacterial stimuli., PMID:40396174
IL-33 alleviates corneal nerve damage in herpes simplex keratitis., PMID:40394801
Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection., PMID:40378045
Spleen and peripheral blood immunopathology in an outbred model of adult-stage murine schistosomiasis., PMID:40375983
Mast cells-intestinal cancer cells crosstalk is mediated by TNF-alpha and sustained by the IL-33/ST2 axis., PMID:40372523
IL1RAP Expression in Human Atherosclerosis: A Target of Novel Antibodies to Reduce Vascular Inflammation and Adhesion., PMID:40371594
[The immunopathology of asthma]., PMID:40371567
Pre-existing epigenetic state and differential NF-κB activation shape type 2 immune cell responses., PMID:40367949
Inhibition of TRPV1 attenuates innate nasal epithelial responses via NF-κB signaling pathway in allergic rhinitis., PMID:40367690
Microneedles Coated with Cow's Milk Proteins: Immunogenicity, Stability, and Safety Assessment., PMID:40366634
Low IL-35 expression in CSF is associated with Neuro-Behcet Disease: Comparative analysis between parenchymal and Non-parenchymal NBD., PMID:40360083
IL-33 secreted from astrocytes alleviates cognitive impairment associated with neuropathic pain via oxidative stress in mice., PMID:40359065
Biological mechanisms and therapeutic prospects of interleukin-33 in pathogenesis and treatment of allergic disease., PMID:40355878
Therapeutic promise of a sulfated (1 → 4) galactan from edible sea grape Caulerpa racemosa: modulation of cytokine expression in lipopolysaccharide-induced CALU-1 cells., PMID:40354863
IL-33/ST2 drives inflammatory pain via CCL2 signaling and activation of TRPV1 and TRPM8., PMID:40348921
Lingguizhugan decoction inhibit pulmonary hypertension by regulating macrophage IL-6 secretion via IL-33/ST2 pathway., PMID:40347929
Analysis of Rare Coding Variants in 470,000 UK Biobank Participants Reveals Genetic Associations With Childhood Asthma Predisposition., PMID:40342259
Liujunzi Decoction Regulated Intestinal Flora Homeostasis to Relieve Lung-Gut Axis Inflammation in Asthma Flora Disorder Mice: Possibly Related to GATA3/ILC2., PMID:40342036
Cytokines and appetite-regulating hormones in human milk and associations with infant growth across four sites in a longitudinal cohort: The Mothers, Infants and Lactation Quality Study., PMID:40338935
Decreased IL-33 Expression in the Cervix in LPS-Induced Preterm Birth and the Potential Role of Mast Cells: A Murine Model., PMID:40328686
Identification and validation of PARK7 as a novel mitochondria-related signature associated with immune microenvironment in asthma., PMID:40319751
Based on the IL-33/ST2-MyD88 signaling pathway to explore the mechanism of aerobic exercise in antagonizing the inflammatory response in depressive mice., PMID:40319714
Inflammasome signaling in astrocytes modulates hippocampal plasticity., PMID:40318630
Decitabine co-operates with the IL-33/ST2 axis modifying the tumor microenvironment and improving the response to PD-1 blockade in melanoma., PMID:40317004
Eosinophils and pleural macrophages counter regulate IL-33-elicited airway inflammation via the 12/15-lipoxygenase pathway., PMID:40313934
Induction of systemic inflammation by welding fume exposure in office workers as well as welders in welding factories., PMID:40307012
The Role of Eosinophils, Eosinophil-Related Cytokines and AI in Predicting Immunotherapy Efficacy in NSCLC., PMID:40305195
Serum sST2, IL-33, and Hcy Expression in Older Adults Patients with Myocardial Infarction and Their Predictive Value for MACE., PMID:40303845
Complex evaluation of coagulation, fibrinolysis, and inflammatory cytokines in SARS-CoV-2 infected pregnant women: a prospective, case-control study., PMID:40303405
Cytokines from parasites: manipulating host responses by molecular mimicry., PMID:40302223
Inflammatory markers in prostate cancer: potential roles in risk stratification and immune profiling., PMID:40296239
For research use only. Not for human or drug use.
