Catalog No.
YHC09401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-His51
Predicted molecular weight
33.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04553
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PRM1, Sperm protamine P1, Cysteine-rich protamine
Development of a procedure for isolation, identification and quality assessment of bovine spermatids and evaluation of their fertilizing ability in vitro., PMID:40453182
Alterations in the abundance of protamine proteoforms related to sperm chromatin packaging, obesity, and age in normozoospermic men., PMID:40411759
BDE-209 toxicity: From spermiogenesis to sexual maturity in F1 male mice., PMID:40311472
High-Throughput Analysis of Postmeiotic Male Germ Cells Using Image Flow Cytometry., PMID:40202661
Development and validation of a deep learning model based on cascade mask regional convolutional neural network to noninvasively and accurately identify human round spermatids., PMID:40185275
Evaluation of TNP1 and PRM1 gene expression in male infertility patients with low or high sperm DNA fragmentation., PMID:40077949
An aberrant protamine ratio is associated with decreased H4ac levels in murine and human sperm., PMID:39999014
Coevolution and Adaptation of Transition Nuclear Proteins and Protamines in Naturally Ascrotal Mammals Support the Black Queen Hypothesis., PMID:39688669
A testis-specific long non-coding RNA, 1700052I22Rik, regulates spermatid chromatin condensation in mice., PMID:39667612
Polymorphism detection and characterization of sperm cells chromatin remodeling associated genes in Murrah buffalo., PMID:39356339
Sperm RNA quantity and PRM1, PRM2 , and TH2B transcript levels reflect sperm characteristics and early embryonic development., PMID:39187928
Adverse Effects of Nicotine on Human Sperm Nuclear Proteins., PMID:39028130
Male infertility and perfluoroalkyl and poly-fluoroalkyl substances: evidence for alterations in phosphorylation of proteins and fertility-related functional attributes in bull spermatozoa†., PMID:38847481
Sodium arsenite impairs sperm quality via downregulating the ZMYND15 and ZMYND10., PMID:38798119
Decreased Ubiquitination and Acetylation of Histones 3 and 4 Are Associated with Obesity-Induced Disorders of Spermatogenesis in Mice., PMID:38668519
Ursonic acid attenuates spermatogenesis in oligozoospermia mice through inhibiting ferroptosis., PMID:38320369
Ameliorative effect of crocin on post-thaw quality, fertility-associated gene expression and fertilization potential of buffalo (Bubalus bubalis) bull sperm., PMID:38268214
Molecular and Functional Characterization of Human Sex-Determining Region on the Y Chromosome Variants Using Protamine 1 Promoter., PMID:38170186
Decabromodiphenyl ether induces the chromosome association disorders of spermatocytes and deformation failures of spermatids in mice., PMID:38135418
Phase-separated CCER1 coordinates the histone-to-protamine transition and male fertility., PMID:38081819
Proteomic analysis of human sperm reveals changes in protamine 1 phosphorylation in men with infertility., PMID:38065301
SPAG17 mediates nuclear translocation of protamines during spermiogenesis., PMID:37766963
Sperm Head Morphology Alterations Associated with Chromatin Instability and Lack of Protamine Abundance in Frozen-Thawed Sperm of Indonesian Local Bulls., PMID:37570242
Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1., PMID:37460896
Identification of heat shock protein70-2 and protamine-1 mRNA, proteins, and analyses of their association with fertility using frozen-thawed sperm in Madura bulls., PMID:37402446
Effect of icariin on the transformation efficiency of induced pluripotent stem cells into sperm cells in vitro., PMID:37399730
Impact of waterpipe and tobacco cigarette smoking on global DNA methylation and nuclear proteins genes transcription in spermatozoa: a comparative investigation., PMID:37145555
Trans differentiating human adipose-derived mesenchymal stem cells into male germ-like cells utilizing Rabbit Sertoli cells: An experimental study., PMID:37122886
Peripheral blood mononuclear cell derived biomarker detection using eXplainable Artificial Intelligence (XAI) provides better diagnosis of breast cancer., PMID:37030103
miRNA Expression Profiles of Mouse Round Spermatids in GRTH/DDX25-Mediated Spermiogenesis: mRNA-miRNA Network Analysis., PMID:36899892
Possible Harmful Effects of Smoking Hookah on Sperm DNA Fragmentation Index and Protamine Genes Expression in Normozoospermic Men., PMID:36618126
Protamine 1 as a secreted colorectal cancer-specific antigen facilitating G1/S phase transition under nutrient stress conditions., PMID:36593375
Abnormal histone replacement following BPA exposure affects spermatogenesis and fertility sequentially., PMID:36347119
Effects of freeze-drying on the quality and fertilising ability of goat sperm recovered from different parts of the epididymis., PMID:36279698
Identification of differentially expressed mRNAs and miRNAs in spermatozoa of bulls of varying fertility., PMID:36277068
Impact of tobacco smoking in association with H2BFWT, PRM1 and PRM2 genes variants on male infertility., PMID:36217675
Carob extract induces spermatogenesis in an infertile mouse model via upregulation of Prm1, Plzf, Bcl-6b, Dazl, Ngn3, Stra8, and Smc1b., PMID:36209951
DMRscaler: a scale-aware method to identify regions of differential DNA methylation spanning basepair to multi-megabase features., PMID:36064314
Protamines: lessons learned from mouse models., PMID:35900356
Proteomic analysis of iTRAQ in melatonin-treated sheep epididymal epithelial cells., PMID:35881670
Rapid divergence of a gamete recognition gene promoted macroevolution of Eutheria., PMID:35821049
Comparative Proteomic Analyses of Poorly Motile Swamp Buffalo Spermatozoa Reveal Low Energy Metabolism and Deficiencies in Motility-Related Proteins., PMID:35804605
Loss of the cleaved-protamine 2 domain leads to incomplete histone-to-protamine exchange and infertility in mice., PMID:35763544
Loss of Prm1 leads to defective chromatin protamination, impaired PRM2 processing, reduced sperm motility and subfertility in male mice., PMID:35608054
PRM1 Gene Expression and Its Protein Abundance in Frozen-Thawed Spermatozoa as Potential Fertility Markers in Breeding Bulls., PMID:35324839
The expression, function, and utilization of Protamine1: a literature review., PMID:35116345
Dynamic Expression and Chromatin Incorporation of ACT and CREM Transcription Factors in Testis Tissues of Infertile Men., PMID:34979062
The potential of sperm bovine protamine as a protein marker of semen production and quality at the National Artificial Insemination Center of Indonesia., PMID:34840468
Spermatozoa retrieval in azoospermia and expression profile of JMJD1A, TNP2, and PRM2 in a subset of the Karachi population., PMID:34235877
RNF8 is not required for histone-to-protamine exchange in spermiogenesis†., PMID:34225362