Catalog No.
AME07701
Biological activity
Measured in a cell proliferation assay using Mouse erythroleukemic cells (TF-1). The ED50 for this effect is 23.9-95.6 ng/mL, corresponding to a specific activity of 1.05×10^4-4.18×10^4 units/mg.
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Ser26-Phe131
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
P20109
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL13, NC30, Interleukin-13, IL-13, Drug Target
The Immunology of Alpha-Gal Syndrome: History, Tick Bites, IgE, and Delayed Anaphylaxis to Mammalian Meat., PMID:40515672
Exploring the Mechanism of Action of Berberine on Arrhythmia After Myocardial Infarction: A Network Pharmacology, Molecular Docking, and Cellular Experimental Study., PMID:40496730
Immunoinflammatory evidence of rheumatoid arthritis caused by COVID-19., PMID:40495223
[Application and research progress of anti-IL-4α monoclonal antibody dupilumab in the treatment of type 2 asthma]., PMID:40491151
Amygdalin Alleviates Airway Inflammation and Remodeling in Asthma Mice: Involvement of TGF-β1/Smads Signaling Pathway., PMID:40485525
Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710
Targeting IL13Rα2 in melanoma with a bispecific T-cell engager: expression profiling and preclinical evaluation., PMID:40484645
Microbiota-derived butyrate alleviates asthma via inhibiting Tfh13-mediated IgE production., PMID:40473603
Local and systemic effects in e-cigarette users compared to cigarette smokers, dual users, and non-smokers., PMID:40468357
Therapeutic mechanism of Jinshui Liujunzi Decoction in treating COPD: targeting the PI3K/Akt signaling pathway., PMID:40466880
The Effect of Thymic Stromal Lymphopoietin on Reflux Esophagitis., PMID:40464554
ILC2 Diversity, Location, and Function in Pulmonary Disease., PMID:40454563
IL-13 priming in precursors drives beige adipogenesis and enhances metabolic homeostasis., PMID:40454479
Suppression of Il5 and Il13 Gene Expression by Synthetic siRNA Molecules Reduces Nasal Hyperreactivity and Inflammation in a Murine Model of Allergic Rhinitis., PMID:40451198
Network pharmacology and experimental validation of inflammation inhibition by ChuanKeZhi Injection in treating asthma., PMID:40450983
Small Proline-Rich Protein 2A Drives Epithelial Remodeling in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps via SAA2 Upregulation., PMID:40447198
Infectious complications of atopic dermatitis, an update., PMID:40447099
Role of HMGB1 on the onset of preeclampsia., PMID:40442700
IL-13 May Could Enhance the Proliferation and Affect the Differentiation of Nasal Epithelium Basal Cells Through the mTOR/p70S6K1 Pathway in Chronic Rhinosinusitis With Nasal Polyps., PMID:40438321
Intranasal Application of Foxp3 Introduced with Poly(d,l-lactic-co-glycolic acid) (PLGA) Nanoparticles (Foxp3 NPs) Attenuates Allergic Inflammation in a Mouse Model of Allergic Rhinitis., PMID:40430867
Impact of Black Soldier Fly Larvae Oil on Immunometabolic Processes., PMID:40429995
Virulence of fowl adenovirus (FAdV) serotype 4 strains impacts cell proliferation and immune response of primary chicken-embryo intestinal epithelial cells., PMID:40426284
FGF-21 fusion proteins ameliorate atopic dermatitis by inhibiting the TLR/TSLP signaling pathway: Anti-inflammatory and skin barrier repair effects., PMID:40424659
Codium fragile Extract Ameliorates Respiratory Function by Controlling Allergic Inflammation in Ovalbumin-Induced Bronchial Disorders in Mice., PMID:40422811
[A comprehensive study of Alzheimer's disease biomarkers in plasma and cerebrospinal fluid]., PMID:40420450
Indolepropionic acid modulates the immune response in allergic rhinitis through the AKT/CEBPB/IL‑10 signaling pathway., PMID:40417918
Secretor and non-secretor human milk oligosaccharides differentially modulate immune response in the presence of cow's milk allergen β-lactoglobulin in an in vitro sensitization model., PMID:40416953
Microarray Patch Based Transdermal Allergen Immunotherapy Prevents Gliadin-induced Anaphylaxis in a Murine Model., PMID:40414810
ITIH4 alleviates OVA-induced asthma by regulating lung-gut microbiota., PMID:40410722
METTL3 regulates ASMCs proliferation and M2 macrophage polarization via mediating the m6A methylation of TIMMDC1 in asthma., PMID:40409178
Stage-Specific Immune Responses to AgB T-Peptides in Patients with Cystic Echinococcosis., PMID:40407653
Airway epithelial cell-specific deletion of EGFR modulates mucoinflammatory features of cystic fibrosis-like lung disease in mice., PMID:40406132
Use of Nemolizumab in the Treatment of Prurigo Nodularis and Atopic Dermatitis., PMID:40403168
Metformin alleviates inflammatory responses in acute allergic asthma by inhibiting ILC2s function., PMID:40398255
Therapeutic potential of Platycodin D in allergic asthma through anti-inflammatory and anti-remodeling effects., PMID:40397997
The alleviating effect of Bai-Ju essence on atopic dermatitis through anti-inflammatory and skin barrier repair mechanisms., PMID:40394445
Unraveling the role of Ctla-4 in intestinal immune homeostasis through a novel Zebrafish model of inflammatory bowel disease., PMID:40392591
Exosomes derived from M2 macrophages regulate airway inflammation by modulating epithelial cell proliferation and apoptosis., PMID:40390011
The potential effect of gut microbiota on the secretion of selected cytokines by human cells in vitro., PMID:40389545
Effect of tacrolimus plus mycophenolate mofetil in the therapy of children with steroid-resistant nephrotic syndrome., PMID:40387047
Comprehensive analysis of protective effects of Loranthus tanakae Franch. and Sav. on ovalbumin-induced atopic dermatitis in mice and TNF-α/INF-γ-stimulated HaCaT cells., PMID:40385597
Effectiveness and safety profiles of percutaneous nephrolithotomy and ureteroscopic lithotripsy for proximal ureteral calculi., PMID:40385045
Plant-based diet, inflammation biomarkers and body composition among women with breast cancer: the Pathways Study., PMID:40384274
Polystyrene nanoplastics aggravate house dust mite induced allergic airway inflammation through EGFR/ERK-dependent lung epithelial barrier dysfunction., PMID:40381396
Soluble TREM2 ameliorates pathological phenotypes in ischemic stroke models via modulating neuronal and microglial functions., PMID:40379866
ILC3s promote intestinal tuft cell hyperplasia and anthelmintic immunity through RANK signaling., PMID:40378237
Complementary Analysis of Local and Systemic Effects of Dupilumab in Paediatric AD Using Tape Strips and Serum., PMID:40375583
Association of STAT6 gene polymorphism with atopic asthma among Yemeni children in Sana'a city, Yemen., PMID:40375219
Alterations in the humoral immunophenotype in sickle cell disease., PMID:40368836
Pre-existing epigenetic state and differential NF-κB activation shape type 2 immune cell responses., PMID:40367949
For research use only. Not for human or drug use.
