Catalog No.
YHC06801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val271-Lys777
Predicted molecular weight
59.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04150
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GR, NR3C1, Nuclear receptor subfamily 3 group C member 1, GRL, Glucocorticoid receptor
DNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls., PMID:40500734
Network Pharmacology-Guided Evaluation of Ginger and Cornelian Cherry Extracts Against Depression and Metabolic Dysfunction in Estrogen-Deficient Chronic Stressed Rats., PMID:40429970
ITGA4 Contributes to 5-Fluorouracil Resistance by Up-Regulating PI3K/AKT Signaling: Evidence from Network Pharmacology, Molecular Docking and Experimental Verification., PMID:40416795
A novel nonsense mutation of the glucocorticoid receptor gene causing glucocorticoid resistance with infertility., PMID:40413280
Long Non-coding RNA NORAD Suppresses Erastin-induced Ferroptosis in Breast Cancer by Upregulating SLC7A11 via Targeting the FUS/NR3C1 Axis-experimental Studies., PMID:40405780
Honokiol in the treatment of triple-negative breast cancer: a network pharmacology approach and experimental validation., PMID:40398092
The interplay between FOXO1 and glucocorticoid signaling in promoting the terminal differentiation of somatotropes., PMID:40381980
Athlete burnout and biomarkers: An exploratory, longitudinal N-of-1 study., PMID:40374022
NR3C1 variants and glucocorticoid response in childhood nephrotic syndrome in North India., PMID:40369478
Identification of ageing-associated gene signatures in heart failure with preserved ejection fraction by integrated bioinformatics analysis and machine learning., PMID:40330147
Interplay between prenatal bisphenol exposure, postnatal maternal care, and offspring sex in predicting DNA methylation relevant to anxiety-like behavior in rats., PMID:40273582
Metabolic syndrome and effect of gene polymorphisms: ADIPOQ, AGT, AGTR1, AGTR2, ApoC-III, NR3C1 and GNB3 gene polymorphisms., PMID:40272664
Epigenetic Echoes: Bridging Nature, Nurture, and Healing Across Generations., PMID:40243774
Integrating thermal proteome profiling and virtual screening to reveal the mechanism of Bletilla striata against osteoclast-driven osteoporosis., PMID:40220420
Genetic association between glucocorticoid receptor gene Bcl1 rs41423247 and rs6198 polymorphisms and risk of obesity in Egyptian children : By., PMID:40200020
HPA-axis multilocus genetic interaction with stress life events in predicting changes in adolescent suicidal ideation., PMID:40139404
Identification and analysis of oxidative stress-related genes in endometriosis., PMID:40124382
Expression and prognosis of NR3C1 in uterine corpus endometrial carcinoma based on multiple datasets., PMID:40113641
Downregulated expression of dual-specificity phosphatase-1 in multiple myeloma as a predictor of poor survival outcomes., PMID:40077895
A polyepigenetic glucocorticoid exposure score and HPA axis-related DNA methylation are associated with gestational epigenetic aging., PMID:40007075
Single cell analysis identifies distinct CD4 + T cells associated with the pathobiology of pediatric obesity related asthma., PMID:40000680
Identifying Sex Differences in Lung Adenocarcinoma Using Multi-Omics Integrative Protein Signaling Networks., PMID:39975108
The effect of Psilocybe cubensis alkaloids on depressive-like behavior in mice exposed to maternal separation with respect to hippocampal gene expression and DNA methylation of Slc6a4 and Nr3c1., PMID:39969076
Drug response is related to NR3C1 and FAAH polymorphism in Chinese pediatric epilepsy patients., PMID:39920787
Association Between Genetically Proxied SLC12A2 Inhibition and Inflammatory Bowel Disease: A Mendelian Randomization Study., PMID:39913044
Vitamin D Receptor rs2228570 Gene Polymorphism Is Associated with Asthma Severity and Exacerbations., PMID:39894560
Advancing Alzheimer's disease pharmacotherapy: efficacy of glucocorticoid modulation with dazucorilant (CORT113176) in preclinical mouse models., PMID:39891319
Lupus and inflammatory bowel disease share a common set of microbiome features distinct from other autoimmune disorders., PMID:39874239
Data Mining Approach to Melatonin Treatment in Alzheimer's Disease: New Gene Targets MMP2 and NR3C1., PMID:39796199
Glucocorticoid receptor gene (NR3C1) methylation, childhood maltreatment, multilevel reward responsiveness and depressive and anxiety symptoms: A neuroimaging epigenetic study., PMID:39778819
The significance of DNA methylation of the NR3C1 gene encoding the glucocorticoid receptor for developing resilience in individuals exposed to early life stress., PMID:39773140
Spatial transcriptome analysis of lung squamous cell carcinoma arising from interstitial pneumonia provides insights into tumor heterogeneity., PMID:39756106
Mongolian medicine Sugemule-7 decoction prevents osteoporosis via Erk1/2 and p38 MAPK signaling pathways according to network pharmacology analysis., PMID:39743063
Network Pharmacology and Molecular Docking Study on the Mechanism of the Therapeutic Effect of Strychni Semen in NSCLC., PMID:39736533
Super-enhancer Activates Master Transcription Factor NR3C1 Expression and Promotes 5-FU Resistance in Gastric Cancer., PMID:39731339
[Glucocorticoid-resistant forms of endocrine ophthalmopathy]., PMID:39731246
Early Life Stress, DNA Methylation of NR3C1 and HSD11B2 , and Oral Feeding Skill Development in Preterm Infants : A Pilot Study., PMID:39724562
Exploring immune gene expression and potential regulatory mechanisms in anaplastic thyroid carcinoma using a combination of single-cell and bulk RNA sequencing data., PMID:39674047
A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury., PMID:39657663
Epigenetics Embedding of Oral Feeding Skill Development in Preterm Infants: A Study Protocol., PMID:39602096
Effect of Short-Term Restraint Stress on the Expression of Genes Associated with the Response to Oxidative Stress in the Hypothalamus of Hypertensive ISIAH and Normotensive WAG Rats., PMID:39594444
The molecular mechanisms of steroid hormone effects on cognitive function., PMID:39549628
The impact of long-term isolation on anxiety, depressive-like and social behavior in aging Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) male rats., PMID:39548293
Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis., PMID:39543086
Transcriptional evidence of HPA axis dysregulation in adolescent females: Unique contributions of chronic early-life stressor exposure and maternal depression history., PMID:39532234
Placental epigenetic signatures of maternal distress in glucocorticoid-related genes and newborn outcomes: A study of Spanish primiparous women., PMID:39504602
Methylome-wide association study of adolescent depressive episode with psychotic symptoms and childhood trauma., PMID:39442698
Mouse liver sinusoidal endothelial cell responses to the glucocorticoid receptor agonist dexamethasone., PMID:39439887
Proteogenomic Landscape of Breast Ductal Carcinoma Reveals Tumor Progression Characteristics and Therapeutic Targets., PMID:39418072
Gene expression of kynurenine pathway enzymes in depression and following electroconvulsive therapy., PMID:39417574
For research use only. Not for human or drug use.
