Anti-Tumor Activities of Anti-Siglec-15 Chimeric Heavy-Chain Antibodies., PMID:40507880
Advancing Non-Invasive Colorectal Cancer Screening: Exploring the Potential of Monoclonal Antibody L2A5., PMID:40243708
Decoding the Molecular Basis of the Specificity of an Anti-sTn Antibody., PMID:39886580
ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment., PMID:39111624
Sialyl-Tn serves as a potential therapeutic target for ovarian cancer., PMID:38566237
Engineering stable and non-immunogenic immunoenzymes for cancer therapy via in situ generated prodrugs., PMID:38368947
A multivalent CD44 glycoconjugate vaccine candidate for cancer immunotherapy., PMID:38301927
Nanoparticles targeting Sialyl-Tn for efficient tyrosine kinase inhibitor delivery in gastric cancer., PMID:37586448
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b., PMID:37311743
Association of Sialyl Tn antigen with cervical cancer lymph node status: An NRG oncology/GOG study., PMID:36827840
Development of an automated chemiluminescent immunoassay for cancer antigen 72-4 and the evaluation of its analytical performance., PMID:36713933
Polymeric nanoparticles targeting Sialyl-Tn in gastric cancer: A live tracking under flow conditions., PMID:36105678
Precise immunological evaluation rationalizes the design of a self-adjuvanting vaccine composed of glycan antigen, TLR1/2 ligand, and T-helper cell epitope., PMID:35873332
Screening and Identification of a Novel Anti-Siglec-15 Human Antibody 3F1 and Relevant Antitumor Activity., PMID:35764384
Glycoproteogenomics characterizes the CD44 splicing code associated with bladder cancer invasion., PMID:35547758
Targeting Tumor Glycans for Cancer Therapy: Successes, Limitations, and Perspectives., PMID:35158915
Fully synthetic Mincle-dependent self-adjuvanting cancer vaccines elicit robust humoral and T cell-dependent immune responses and protect mice from tumor development., PMID:35024123
Combined Action of Anti-MUC1 Monoclonal Antibody and Pyrazole-Platinum(II) Complexes Reveals Higher Effectiveness towards Apoptotic Response in Comparison with Monotherapy in AGS Gastric Cancer Cells., PMID:34206951
Anti-cancer effect of combined action of anti-MUC1 and rosmarinic acid in AGS gastric cancer cells., PMID:33930385
A biotechnological tool for glycoprotein desialylation based on immobilized neuraminidase from Clostridium perfringens., PMID:33732900
Isoforms of MUC16 activate oncogenic signaling through EGF receptors to enhance the progression of pancreatic cancer., PMID:33359791
High-mannose type N-glycans with core fucosylation and complex-type N-glycans with terminal neuraminic acid residues are unique to porcine islets., PMID:33170858
Rhamnose modified bovine serum albumin as a carrier protein promotes the immune response against sTn antigen., PMID:33079080
Synthesis of MUC1-derived glycopeptide bearing a novel triazole STn analog., PMID:33010570
Shigella flexneri Targets Human Colonic Goblet Cells by O Antigen Binding to Sialyl-Tn and Tn Antigens via Glycan-Glycan Interactions., PMID:32926786
Engineering orthogonal human O-linked glycoprotein biosynthesis in bacteria., PMID:32719555
Siglec-15 recognition of sialoglycans on tumor cell lines can occur independently of sialyl Tn antigen expression., PMID:32501471
Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers., PMID:32370811
Cross-talk between Colon Cells and Macrophages Increases ST6GALNAC1 and MUC1-sTn Expression in Ulcerative Colitis and Colitis-Associated Colon Cancer., PMID:31831633
Products of Chemoenzymatic Synthesis Representing MUC1 Tandem Repeat Unit with T-, ST- or STn-antigen Revealed Distinct Specificities of Anti-MUC1 Antibodies., PMID:31719620
Europium Nanoparticle-Based Sialyl-Tn Monoclonal Antibody Discriminates Epithelial Ovarian Cancer-Associated CA125 from Benign Sources., PMID:31659068
Fluorine-modified sialyl-Tn-CRM197 vaccine elicits a robust immune response., PMID:31267246
A Polymeric Nanogel-Based Treatment Regimen for Enhanced Efficacy and Sequential Administration of Synergistic Drug Combination in Pancreatic Cancer., PMID:30683666
Cancer-associated mucins: role in immune modulation and metastasis., PMID:30618016
Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2-6 sialic acids., PMID:30111774
Humanized anti-Sialyl-Tn antibodies for the treatment of ovarian carcinoma., PMID:30052649
A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen., PMID:30018351
Treatment of ovarian cancer by targeting the tumor stem cell-associated carbohydrate antigen, Sialyl-Thomsen-nouveau., PMID:29796189
Syntheses and Immunological Evaluation of Self-Adjuvanting Clustered N-Acetyl and N-Propionyl Sialyl-Tn Combined with a T-helper Cell Epitope as Antitumor Vaccine Candidates., PMID:29768704
Serum sialylation changes in cancer., PMID:29680984
Analysis of sialyl-Lewis x on MUC5AC and MUC1 mucins in pancreatic cancer tissues., PMID:29408556
Chemobacterial Synthesis of a Sialyl-Tn Cyclopeptide Vaccine Candidate., PMID:28632300
A cancer vaccine based on fluorine-modified sialyl-Tn induces robust immune responses in a murine model., PMID:28537884
Epitope mapping of a new anti-Tn antibody detecting gastric cancer cells., PMID:28419225
Novel anti-Sialyl-Tn monoclonal antibodies and antibody-drug conjugates demonstrate tumor specificity and anti-tumor activity., PMID:28281872
Effect of blood type on anti-α-Gal immunity and the incidence of infectious diseases., PMID:28280265
IgG Antibody Response Elicited by a Fully Synthetic Two-Component Carbohydrate-Based Cancer Vaccine Candidate with α-Galactosylceramide as Built-in Adjuvant., PMID:28121454
Innate immune defense in the inner ear - mucines are expressed by the human endolymphatic sac., PMID:28106268
Sialyl-Tn Polysaccharide A1 as an Entirely Carbohydrate Immunogen: Synthesis and Immunological Evaluation., PMID:27726393
Synthesis and immunological evaluation of MUC1 glycopeptide conjugates bearing N-acetyl modified STn derivatives as anticancer vaccines., PMID:27380866
For research use only. Not for human or drug use.
