Catalog No.
PHJ58601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SMURF2 (His246-Glu400).
Target
SMAD ubiquitination regulatory factor 2, hSMURF2, HECT-type E3 ubiquitin transferase SMURF2, SMURF2, SMAD-specific E3 ubiquitin-protein ligase 2, E3 ubiquitin-protein ligase SMURF2
Purification
Antigen affinity purification.
Accession
Q9HAU4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
TRAF4 hyperactivates HER2 signaling and contributes to Trastuzumab resistance in HER2-positive breast cancer., PMID:35864174
LncRNA FIRRE stimulates PTBP1-induced Smurf2 decay, stabilizes B-cell receptor, and promotes the development of diffuse large B-cell lymphoma., PMID:35416325
The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treated with Lipopolysaccharide A., PMID:32774143
Challenges for Super-Resolution Localization Microscopy and Biomolecular Fluorescent Nano-Probing in Cancer Research., PMID:28956810
Comprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancer., PMID:26567849
[Biologic agents for the treatment of rheumatic diseases]., PMID:24870843
Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-β signaling., PMID:22707713
Ubiquitination of heat shock protein 27 is mediated by its interaction with Smad ubiquitination regulatory factor 2 in A549 cells., PMID:21967197
Smad ubiquitination regulatory factor-2 in progressive supranuclear palsy., PMID:20819168
[Platelet-derived growth factor-BB inhibited p21(WAF1) expression partially through transforming growth factor-beta signalling system in vascular smooth muscle cell]., PMID:20398565
Opposing effects of Arkadia and Smurf on TGFbeta1-induced IgA isotype expression., PMID:17978583
Platelet-derived growth factor BB modulates PCNA protein synthesis partially through the transforming growth factor beta signalling pathway in vascular smooth muscle cells., PMID:17901902
Smurf2 up-regulation activates telomere-dependent senescence., PMID:15574587
The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase., PMID:14562029
Ubiquitin-dependent degradation of Smad2 is increased in the glomeruli of rats with anti-thymocyte serum nephritis., PMID:14507671
Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover., PMID:12717440
For research use only. Not for human or drug use.
