Catalog No.
PHA58702
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PLXNB1 (Cys1067-Asp1251).
Target
SEP, Semaphorin receptor SEP, PLXN5, PLXNB1, Plexin-B1, KIAA0407
Purification
Antigen affinity purification.
Accession
O43157
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A phase 1/2 study of pepinemab in children, adolescents, or young adults with recurrent or refractory solid tumors: A children's oncology group consortium report (ADVL1614)., PMID:38520670
Semaphorin4A promotes lung cancer by activation of NF-κB pathway mediated by PlexinB1., PMID:37901456
Osteosarcoma-Associated Immune Genes as Potential Immunotherapy and Prognosis Biomarkers., PMID:37452172
De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function., PMID:35981535
An antagonistic monoclonal anti-Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis., PMID:35850304
SEMA4D/PlexinB1 promotes AML progression via activation of PI3K/Akt signaling., PMID:35794581
Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy., PMID:31943789
Semaphorin 4A Stabilizes Human Regulatory T Cell Phenotype via Plexin B1., PMID:31236543
CD100-plexin-B1 induces epithelial-mesenchymal transition of head and neck squamous cell carcinoma and promotes metastasis., PMID:30981760
Facile Synthesis of Dimeric Thioether-Macrocyclic Peptides with Antibody-like Affinity against Plexin-B1., PMID:29714478
Tracking Differential Endocytosis and Trafficking of Semaphorin Receptor Complexes in Responding Nerve Growth Cones., PMID:27787860
Tax and Semaphorin 4D Released from Lymphocytes Infected with Human Lymphotropic Virus Type 1 and Their Effect on Neurite Growth., PMID:26389656
Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into Tumor and Enhances Response to Other Immunomodulatory Therapies., PMID:25614511
Circulating semaphorin-4D and plexin-B1 levels in postmenopausal women with low bone mass: the 3-month effect of zoledronic acid, denosumab or teriparatide treatment., PMID:25395071
Semaphorin 4D expression is associated with a poor clinical outcome in cervical cancer patients., PMID:24603190
Phage display identification of CD100 in human atherosclerotic plaque macrophages and foam cells., PMID:24098722
The class 4 semaphorin Sema4D promotes the rapid assembly of GABAergic synapses in rodent hippocampus., PMID:23699507
Plexin-B1: a potential diagnostic biomarker for glioma and a future target for glioma immunotherapy., PMID:22939532
Suppression of bone formation by osteoclastic expression of semaphorin 4D., PMID:22019888
Axon growth and guidance genes identify nascent, immature, and mature olfactory sensory neurons., PMID:20882566
Co-expression of plexin-B1 and Met in human breast and ovary tumours enhances the risk of progression., PMID:19940359
Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis., PMID:19689741
Progesterone receptor A and c-Met mediates spheroids-endometrium attachment., PMID:19220894
Human uterine epithelial RL95-2 and HEC-1A cell-line adhesiveness: the role of plexin B1., PMID:17383649
Semaphorin-4D (Sema-4D), the Plexin-B1 ligand, is involved in mouse ovary follicular development., PMID:17376242
Semaphorin 4D provides a link between axon guidance processes and tumor-induced angiogenesis., PMID:16754882
Expression of plexin-B1 in the mouse ovary and its possible role in follicular development., PMID:16210013
CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival., PMID:15613544
Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B., PMID:15289326
Mesothelial differentiation as reflected by differential gene expression., PMID:14551161
For research use only. Not for human or drug use.
