Catalog No.
PQD85401
Species reactivity
Dog
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Dog CD154/CD40L (Met112-Leu260).
Target
sCD40L, Tumor necrosis factor ligand superfamily member 5, T-cell antigen Gp39, CD40L, TNFSF5, CD154, CD40-L, TNF-related activation protein, CD40 ligand, CD40LG, TRAP
Purification
Antigen affinity purification.
Accession
O97626
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Human memory CD4+ T cell response to the major dog allergen Can f 5, prostatic kallikrein., PMID:26684878
Targeting the HA2 subunit of influenza A virus hemagglutinin via CD40L provides universal protection against diverse subtypes., PMID:25052763
Treatment efficacy and immune stimulation by AdCD40L gene therapy of spontaneous canine malignant melanoma., PMID:23799414
Pharmacological immunosuppression reduces but does not eliminate the need for total-body irradiation in nonmyeloablative conditioning regimens for hematopoietic cell transplantation., PMID:21220032
A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo., PMID:19786146
Establishment of long-term tolerance to SRBC in dogs by recombinant canine CTLA4-Ig., PMID:19667932
Development and in vitro characterization of canine CD40-Ig., PMID:18387675
CD40 ligand supports the long-term maintenance and differentiation of chicken B cells in culture., PMID:18374414
Characterization of canine monocyte-derived dendritic cells with phenotypic and functional differentiation., PMID:17695590
CD154 blockade and donor-specific transfusions in DLA-identical marrow transplantation in dogs conditioned with 1-Gy total body irradiation., PMID:17241922
Targeting with bovine CD154 enhances humoral immune responses induced by a DNA vaccine in sheep., PMID:12517965
In vitro IgE but not IgG production of canine peripheral blood B cells is inhibited by CD40 ligation., PMID:10889305