Catalog No.
PXX06701
Species reactivity
Treponema pallidum (strain Nichols)
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Treponema pallidum TPP17 (Cys22-Lys156).
Target
17 kDa lipoprotein, tpp17, TP_0435, Treponema Pallidum (TP,Syphilis)
Purification
Antigen affinity purification.
Accession
P29722
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Development of an automated processing platform based on luciferase fused TPP17 to detect specific Treponema pallidum antibody in clinical serum with high sensitivity and rapidity., PMID:39537062
Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis., PMID:32936831
Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-kappa B., PMID:8751937
Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphiphilicity., PMID:8454324
For research use only. Not for human or drug use.
