Catalog No.
PHE87201
Species reactivity
Human,Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CLCN7 (Phe597-Thr805).
Target
Chloride channel 7 alpha subunit, CLCN7, ClC-7, Chloride channel protein 7, H(+)/Cl(-) exchange transporter 7
Purification
Antigen affinity purification.
Accession
P51798
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Null mutation of chloride channel 7 (Clcn7) impairs dental root formation but does not affect enamel mineralization., PMID:26346547
Antibodies against ClC7 inhibit extracellular acidification-induced Cl⁻ currents and bone resorption activity in mouse osteoclasts., PMID:21061117
Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB., PMID:18313864
The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor., PMID:17105730
Activation by acidic pH of CLC-7 expressed in oocytes from Xenopus laevis., PMID:11846422
A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption., PMID:8969232
For research use only. Not for human or drug use.
