Catalog No.
PHD49801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PCMT1 (Met1-Lys227).
Target
PIMT, L-isoaspartyl protein carboxyl methyltransferase, PCMT1, Protein-L-isoaspartate(D-aspartate) O-methyltransferase, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase
Purification
Antigen affinity purification.
Accession
P22061
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Immunotherapy targeting isoDGR-protein damage extends lifespan in a mouse model of protein deamidation., PMID:37971164
Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis., PMID:35033172
Protein Kinase C Theta Modulates PCMT1 through hnRNPL to Regulate FOXP3 Stability in Regulatory T Cells., PMID:32592691
Construction of random tumor transcriptome expression library for creating and selecting novel tumor antigens., PMID:27449040
Chaperone protein L-isoaspartate (D-aspartyl) O-methyltransferase as a novel predictor of poor prognosis in lung adenocarcinoma., PMID:26997432
Methylation of histone H4 at aspartate 24 by protein L-isoaspartate O-methyltransferase (PCMT1) links histone modifications with protein homeostasis., PMID:25327473
Post-translational protein modifications in type 1 diabetes: a role for the repair enzyme protein-L-isoaspartate (D-aspartate) O-methyltransferase?, PMID:17216280
Proteomic identification of novel substrates of a protein isoaspartyl methyltransferase repair enzyme., PMID:16923807
DTL, the Drosophila homolog of PIMT/Tgs1 nuclear receptor coactivator-interacting protein/RNA methyltransferase, has an essential role in development., PMID:15684427
Different isoforms of PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase localizes to the cytoplasm and nucleus., PMID:12943661
For research use only. Not for human or drug use.
