Catalog No.
YMC83402
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Asn20-Leu150
Predicted molecular weight
17.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P31041
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cd28, T-cell-specific surface glycoprotein CD28
From Molecular Precision to Clinical Practice: A Comprehensive Review of Bispecific and Trispecific Antibodies in Hematologic Malignancies., PMID:40508128
Divergent Immune Pathways in Coronary Artery Disease and Aortic Stenosis: The Role of Chronic Inflammation and Senescence., PMID:40508061
CliniMACS Prodigy Manufacturing of Switchable, AND-Gate CAR T Cells., PMID:40507834
PD-1 is conserved from sharks to humans: new insights into PD-1, PD-L1, PD-L2, and SHP-2 evolution., PMID:40503235
TRIC-Based High-Throughput Screening Enables the Discovery of Small Molecule CD28 Binders., PMID:40501875
Expression of the Transcription Factor FOXP3 in Human Peripheral Blood B-Cell Subtypes (CD19+CD39+ and CD19+CD39-) and Evaluation of Their Regulatory Function., PMID:40497715
Differential susceptibility and role for senescence in CART cells based on costimulatory domains., PMID:40495168
Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer., PMID:40492347
The potential role of biomarkers CD28 and PF4 in the pathogenesis of idiopathic pulmonary fibrosis and their impact on the prognosis: an immune microenvironment analysis., PMID:40483519
CTLA-4 blockade in ovarian cancer immunotherapy: Mechanisms and clinical strategies., PMID:40482550
Aptamers as therapeutic targets: prospects and progress in the treatment of cancers., PMID:40479828
The immunosuppressive effect of glucocorticoids in human primary T cells is mainly mediated via a rapid inhibition of the IL-2/IL-2R signaling axis., PMID:40468327
IFN-γ-resistant CD28 CAR T cells demonstrate increased survival, efficacy, and durability in multiple murine tumor models., PMID:40465687
Effects of kidney-tonifying Chinese herbs on thymus regen-eration after rapamycin-induced degeneration in mice., PMID:40461290
Effective CAR T-cell targeting of an MUC1 cleavage product., PMID:40447312
Ovalbumin-specific regulatory T cells differentiated from the naïve phenotype (CD44loCD62Lhi) in mesenteric lymph nodes stably suppress enteropathy even in severe food-allergic mice., PMID:40446078
Xuanfei Baidu Formula confers protection against viral pneumonia by modulating CD8+ T cell proliferation via MAPK signalling pathway., PMID:40440907
The Presence of Non-Exhausted Senescent T Cells in Breast Cancer Patients., PMID:40439375
Efficacy and safety of third-generation CD19-CAR T cells incorporating CD28 and TLR2 intracellular domains for B-cell malignancies with central nervous system involvement: results of a pivotal trial., PMID:40426201
Dual roles of IRE1α inhibition in reversing mitochondrial ROS-induced CD8+ T-cell senescence and exerting direct antitumor effects in multiple myeloma., PMID:40425229
Chimeric Autoantibody Receptor- and/or Peptide-MHC-Based CAR Therapies for Targeted Elimination of Antigen-Specific B or T Cells in Hypersensitivity Disorders Such as Allergies and Autoimmune Diseases., PMID:40422256
Engineering safe anti-CD19-CD28ζ CAR T cells with CD8a hinge domain in serum-free media for adoptive immunotherapy., PMID:40416968
Tumor suppressing function of SLC16A7 in bladder cancer and its pan-cancer analysis., PMID:40410718
A CARMIL2 gain-of-function mutation suffices to trigger most CD28 costimulatory functions in vivo., PMID:40402149
Dap10 co-stimulation enhances the anti-HCC efficacy of NKp30 chimeric antigen receptor T cells., PMID:40393250
CD28 and CTLA4 polymorphisms associated with ankylosing spondylitis: a study in the context of HLA-B27., PMID:40389847
Exploring the link between Co-stimulatory gene polymorphisms and clinical manifestations in Graves' ophthalmopathy., PMID:40379199
TIGIT deficiency promotes autoreactive CD4+ T-cell responses through a metabolic‒epigenetic mechanism in autoimmune myositis., PMID:40374622
CD28+ CD45RA- CD8br AC mediated the effects of Interleukin- 6 on Alzheimer's disease: A Mendelian Randomization Study., PMID:40369481
Treg Control of CD80/CD86 Expression Mediates Immune System Homeostasis., PMID:40346769
Hematologic and lymphatic disorders associated with chimeric antigen receptor T-cell therapy: a pharmacovigilance analysis of the FDA adverse event reporting system (FAERS) database., PMID:40346502
The Role of Abatacept on Inflammation and Fibrosis in Hypochlorous Acid-Induced Fibrosis Mice., PMID:40344312
Peripheral immune cell response to stimulation stratifies Parkinson's disease progression from prodromal to clinical stages., PMID:40341772
PD-1 blockade employed at the time CD8+ T cells are activated enhances their antitumor efficacy., PMID:40341032
Immunomodulatory effects of dental pulp stem cells on lymphocytes and monocytes from patients with rheumatoid arthritis., PMID:40338061
CD27 costimulation supports metabolic fitness of CD4+ T cells by enhancing de novo nucleotide and protein synthesis., PMID:40324771
Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and TYK2 Inhibitors via IL10 Antagonism., PMID:40320905
Influence of polyfunctional Tbet+ T cells on specific clinical events in chronic lymphocytic leukaemia., PMID:40313965
A novel immortalization method for immortalizing human primary CD8+ T cells by inserting a single copy of human telomerase reverse transcriptase via CRISPR/Cas9., PMID:40311322
Novel diagnostic biomarker and immune profiling of GPR56+ B cell subsets in systemic lupus erythematosus., PMID:40311320
Improvement in the function of self-activating chimeric antigen receptor by replacing the linker sequence., PMID:40308593
The Potential Inflammatory Role of IL-6 Signalling in Perturbing the Energy Metabolism Function by Stimulating the Akt-mTOR Pathway in Jurkat T Cells., PMID:40308199
Progressive accumulation of circulating CD27-CD28- effector/memory CD8+ T cells in patients with lung cancer blunts responses to immune checkpoint inhibitor therapy., PMID:40307573
Treatment Efficacy and Molecular Dynamics of Neoadjuvant Durvalumab and Olaparib in Resectable Urothelial Bladder Cancer: The NEODURVARIB Trial., PMID:40298406
Impact of alcohol consumption on outcomes and potential of immune biomarkers for postoperative complications in trauma patients., PMID:40297586
A Simple and Efficient Method for Testing Immunomodulatory Agents for Generation of Tolerogenic Dendritic Cells from Human CD14+ Monocytes., PMID:40293944
Peripheral T-cell subset activation in NMDAR encephalitis: Insights into pathogenesis and biomarker potential for disease monitoring., PMID:40288549
Identification of host factors affecting Chicken Infectious Anemia Virus infection and pathogenicity through RNA-seq and LC-MS., PMID:40279723
MUC18-Directed chimeric antigen receptor T cells for the treatment of mucosal melanoma., PMID:40275251
Activated blood-derived human primary T cells support replication of HAdV C5 and virus transmission to polarized human primary epithelial cells., PMID:40265914
For research use only. Not for human or drug use.
