Catalog No.
YHB91201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser82-Ser192
Predicted molecular weight
14.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01127
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PDGF-2, Proto-oncogene c-Sis, PDGF2, SIS, Platelet-derived growth factor B chain, PDGFB, Becaplermin, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, PDGF subunit B
MAFB: a key regulator of myeloid commitment involved in hematological diseases., PMID:40506426
A spatially organized Cd24a+/Pax9+ stem cell core governs postnatal tooth establishment., PMID:40479070
Substrate stiffness modifies gene expression and transcriptional response of equine endometrial fibroblasts to TGF-β1., PMID:40460762
Macrophage depletion in male mice impairs extraction socket healing by disrupting bone regeneration and tissue repair., PMID:40441056
Mechanical and biological properties of 3D-printed porous titanium scaffolds coated with composite growth factors., PMID:40426159
Independent and interactive associations of inflammation, vascular homeostasis markers, and childhood trauma with suicide attempt history., PMID:40420573
Cellular crosstalk mediated by Meteorin-like regulating hepatic stellate cell activation during hepatic fibrosis., PMID:40393967
Synergistic Effects of Insulin-like Growth Factor-1 and Platelet-Derived Growth Factor-BB in Tendon Healing., PMID:40362278
The role of the PDGF-BB/PDGFR-β signaling pathway in microcirculatory disturbances and BBB destruction after experimental subarachnoid hemorrhage in mice., PMID:40345321
PDGF-Releasing Hydrogels for Enhanced Proliferation of Human Nucleus Pulposus Cells., PMID:40344482
Programmable hierarchical hydrogel dressing for sequential release of growth factor and DNase to accelerate diabetic wound healing., PMID:40339657
CIAPIN1 promotes proliferation and migration of PDGF-BB-activated airway smooth muscle cells via the PI3K/AKT and JAK2/STAT3 signaling pathways., PMID:40338178
LONP1 facilitates pulmonary artery smooth muscle cell glycolytic reprogramming by degrading MPC1 in pulmonary hypertension., PMID:40332105
Enhancer-Associated LncRNA-ITGA2 Promotes Vascular Remodeling Through ITGA2., PMID:40321134
PDGF-BB promotes oral submucosal fibrosis by driving phenotypic transformation and autophagy in oral mucosal fibroblasts through downregulation of circHIPK3., PMID:40316684
Integrated GWAS and metabolomic analyses identified metabolic pathways and candidate genes involved in free asparagine accumulation in durum wheat grain., PMID:40306232
Genome-wide association study to identify biological and metabolic pathways associated with carcass portion weights in turkeys: GWAS OF TURKEY CARCASS PORTION WEIGHTS., PMID:40300320
Expression of platelet derived growth factor (PDGF) ligands and receptors in the ovine ovary and effects of PDGFBB on granulosa cell function., PMID:40294218
Platelet-derived growth factor subunit B overexpression promotes lung cancer tumor growth and metastasis: The role of glucose metabolism., PMID:40260069
CDCP1 knockdown suppresses PDGFRβ/AKT pathway-mediated vascular smooth muscle cell proliferation by inhibiting PDGFRβ endocytosis., PMID:40256729
Smooth muscle extracellular matrix modified small intestinal submucosa conduits promote peripheral nerve repair., PMID:40253732
LINC00426 promotes the progression of atherosclerosis by regulating miR-873-5p/SRRM2 axis., PMID:40233646
Circularized Supramolecular Spherical Nucleic Acids Alleviates Liver Fibrosis through Blocking Upstream Activation and Reversing Activation State of Hepatic Stellate Cells., PMID:40228167
Multilayer Film with Bioactive and Antiadhesive Layers for Accelerated Tendon Regeneration., PMID:40195577
Integrating Raman spectroscopy and RT-qPCR for enhanced diagnosis of thyroid lesions: A comparative study of biochemical and molecular markers., PMID:40179617
IL13RA2-integrated genetically engineered mouse model allows for CAR T cells targeting pediatric high-grade gliomas., PMID:40176156
Evaluation of the effect of platelet-derived growth factor-BB on the biological activity of human mandibular bone marrow-derived mesenchymal stem cells., PMID:40168781
Sodium Hyaluronate-PDGF Repairs Cartilage and Subchondral Bone Microenvironment via HIF-1α-VEGF-Notch and SDF-1-CXCR4 Inhibition in Osteoarthritis., PMID:40159624
3D-Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB-LG4 Fusion Protein Promotes Bone Regeneration., PMID:40145866
A Novel Molecular Regulatory Network in Bone Marrow Mesenchymal Stem Cells for Age-Related Osteoporosis., PMID:40145611
Effects of a PDGF-stem cell-hydrogel compound on skin wound healing in mice., PMID:40121568
Biodegradable nano-immune agonist for enhanced immunotherapy of melanoma via the synergistic action of cuproptosis and cGAS-STING enhanced immune response., PMID:40120375
Long-term consumption of moderate amounts of sucrose-sweetened drinks disrupts intestinal barrier function by impairing goblet cell differentiation., PMID:40072586
Combining the RCAS/tv-a retrovirus and CRISPR/Cas9 gene editing systems to generate primary mouse models of diffuse midline glioma., PMID:40056601
Recombinant human platelet-derived growth factor-BB-mediated reconstructive therapy of advanced peri-implantitis bone defects: A case series., PMID:40047362
Activation of AMP-activated Protein Kinase by Metformin Inhibits Dedifferentiation of Platelet-derived Growth Factor-BB-induced Vascular Smooth Muscle Cells to Improve Arterial Remodeling in Cirrhotic Portal Hypertension., PMID:40024535
The Role of Luteolin in Inhibiting Prostaglandin-Endoperoxide Synthase 2 to Relieve Neointimal Hyperplasia in Arteriovenous Fistula., PMID:39960128
Genomic Profiling Uncovers a Broader Spectrum of Dermatofibrosarcoma Protuberans: Implications for Diagnosis and Therapy., PMID:39956270
Comparative Assessment of Acute Pulmonary Effects Induced by Heat-Not-Burn Tobacco Aerosol Inhalation in a Murine Model., PMID:39940903
Improved tendon repair with optimized chemically modified mRNAs: Combined delivery of Pdgf-BB and IL-1Ra using injectable nanoparticles., PMID:39938707
Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB-Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer., PMID:39937190
YTH N6-methyladenosine RNA Binding Protein 1 Inhibits Smooth Muscle Cell Phenotypic Modulation and Neointimal Hyperplasia., PMID:39936952
Fabrication, characterization, and application of gelatin/alginate-based hydrogels incorporating selenium-doped deferoxamine-derived carbon quantum dots: In vitro and in vivo studies., PMID:39909275
Integrated Transcriptomic and Metabolomic Analysis of Rat PASMCs Reveals the Underlying Mechanism for Pulmonary Arterial Hypertension., PMID:39901736
Deletion of smooth muscle ZFP36 promotes neointimal hyperplasia in mice., PMID:39890944
Hsa_circ_0001304 promotes vascular neointimal hyperplasia accompanied by autophagy activation., PMID:39881153
Dual recycling signal amplification strategy based on autocatalytic entropy-driven circuit and DNAzyme for colorimetric detection of platelet-derived growth factor-BB., PMID:39871664
hUC-MSCs Prevent Acute High-Altitude Injury through Apoe/Pdgf-b/p-Erk1/2 Axis in Mice., PMID:39871082
Semaphorin-4D signaling in recruiting dental stem cells for vascular stabilization., PMID:39865283
Assessment of the Utility of Selected Inflammatory Markers in Correlation with Magnetic Resonance Enterography (MRE) Findings in the Diagnosis of Crohn's Disease., PMID:39858510
For research use only. Not for human or drug use.
