Catalog No.
YHB74001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser112-Thr270
Predicted molecular weight
20.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95760
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11
Do not be alarmed: understanding IL33-ST2 signalling in wound repair. PMID: 26519250
The IL33/ST2 axis in Sjogren syndrome in relation to disease activity. PMID: 27097949
IL-33 reduces tumor growth in models of colorectal cancer with the help of eosinophils. PMID: 32923137
The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. PMID: 27150562
Interleukin 33 Triggers Early Eosinophil-Dependent Events Leading to Metaplasia in a Chronic Model of Gastritis-Prone Mice. PMID: 33010253
IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation. PMID: 31562870
An Autocrine Circuit of IL-33 in Keratinocytes Is Involved in the Progression of Psoriasis. PMID: 32853659
NLRP12- and NLRC4-mediated corneal epithelial pyroptosis is driven by GSDMD cleavage accompanied by IL-33 processing in dry eye. PMID: 32735949
TSLP and IL-33 reciprocally promote each other's lung protein expression and ILC2 receptor expression to enhance innate type-2 airway inflammation. PMID: 31975538
Correlations between serum IL33 and tumor development: a meta-analysis. PMID: 24870747
IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy. PMID: 27821781
IL (Interleukin)-33 Suppresses Abdominal Aortic Aneurysm by Enhancing Regulatory T-Cell Expansion and Activity. PMID: 30651000
IL33 rs1342326 polymorphism, though associated with severe post-bronchiolitis asthma, showed no association with lung function. PMID: 33713391
STING activation in alveolar macrophages and group 2 innate lymphoid cells suppresses IL-33-driven type 2 immunopathology. PMID: 33400692
Estrogen receptor-alpha signaling increases allergen-induced IL-33 release and airway inflammation. PMID: 32648964
A novel stromal lncRNA signature reprograms fibroblasts to promote the growth of oral squamous cell carcinoma via LncRNA-CAF/interleukin-33. PMID: 29346528
Sex drives Tregs into fat. PMID: 32245886
[Regulation of IL33 Gene Expression by SP1 and Foxa1 in Breast and Lung Cancer Cells]. PMID: 33566030
IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-kappaB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation. PMID: 29329586
ST2 Signaling in the Tumor Microenvironment. PMID: 32060890
[INTERLEUKIN-33 IN ALLERGIC DISEASES]. PMID: 28025417
[Interleukin-33: from biology to potential treatments]. PMID: 31115327
The essential function of IL-33 in metabolic regulation. PMID: 32445465
[Research progress of interleukin-33 and its receptor ST2 in sepsis]. PMID: 33463506
[Advances of IL-33/ST2 signaling pathway in allergic rhinitis]. PMID: 32842193
Interleukin-33: increasing role in dermatological conditions. PMID: 26969580
Paeoniflorin suppresses IL-33 production by macrophages. PMID: 32312124
IL-33 and kidney disease (Review). PMID: 26548720
Role of IL-33 in transplant biology. PMID: 31486398
Host-specific vascular endothelial cell responses to Angiostrongylus vasorum: a comparative in vitro study in red foxes (Vulpes vulpes) and domestic dogs., PMID:40529303
Proteomic analysis of human kidney biopsies unveils emerging acute kidney injury very early after liver graft reperfusion., PMID:40524147
Expression of IL-33 in rodent testes and its role in Leydig cell steroidogenesis and aging., PMID:40521800
Proteomic profiling reveals immunomodulatory role of IL-33 in ocular bacterial and fungal infections., PMID:40512033
Modeling Human Airway Epithelial Barrier Penetration Using Birch Bet v 1 and Alder Aln g 1 Pollen Allergens During Sensitization Process., PMID:40507979
Respiratory Syncytial Virus Infection Disrupts Airway Epithelial Barriers via IL-33/ST2/MyD88 Signaling Axis., PMID:40497542
Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710
The glycocalyx of Lacticaseibacillus paracasei NPB01 presents two different rhamnose-rich polysaccharides with non-equivalent immunomodulating activities., PMID:40484587
Effect of adaptive servo-ventilation on circulating biomarkers in patients with sleep apnoea after myocardial infarction: results of an ancillary analysis of the randomised TEAM-ASV I trial., PMID:40479758
Effect of EP395, a novel anti-inflammatory macrolide, in an inhaled lipopolysaccharide challenge model in healthy volunteers: a randomised controlled trial., PMID:40466859
A tryptophol-containing emulgel ameliorates imiquimod-induced mice psoriasis., PMID:40461662
Unveiling the Intricate Causal Nexus Between 91 Circulating Inflammatory Proteins and Perianal Abscess Through a Comprehensive Bidirectional Two-Sample Mendelian Randomization Analysis., PMID:40453734
Alleviation of dextran sulfate sodium (DSS)-induced colitis in mice through the antioxidative effects of muscone via the MyD88/p38 MAPK signalling pathway., PMID:40452925
Small Proline-Rich Protein 2A Drives Epithelial Remodeling in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps via SAA2 Upregulation., PMID:40447198
Potential Inflammatory Mediators in Pericardial Fluids of Patients With Coronary Artery Diseases and Their Association With Plasma Biomarkers., PMID:40437664
In Silico Analysis of Novel circRNA-miRNA-mRNA Axis in BRAFV600E Melanoma: Implications for Primary to Metastasis Transformation and TIME Modulation., PMID:40436810
[Not Available]., PMID:40433883
Codium fragile Extract Ameliorates Respiratory Function by Controlling Allergic Inflammation in Ovalbumin-Induced Bronchial Disorders in Mice., PMID:40422811
Immune, metabolic, anatomical, and functional features of people after successful tuberculosis treatment: an exploratory analysis., PMID:40419526
Enhancing the Affinity of a Novel Selective scFv for Soluble ST2 through Computational Design., PMID:40417773
Targeting of the IL-33/Wnt axis restricts breast cancer stemness and metastasis., PMID:40414980
Metformin alleviates inflammatory responses in acute allergic asthma by inhibiting ILC2s function., PMID:40398255
Differential activation of monocytes and PMNs in orofacial granulomatosis patients induced by bacterial and non-bacterial stimuli., PMID:40396174
IL-33 alleviates corneal nerve damage in herpes simplex keratitis., PMID:40394801
Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection., PMID:40378045
Spleen and peripheral blood immunopathology in an outbred model of adult-stage murine schistosomiasis., PMID:40375983
Mast cells-intestinal cancer cells crosstalk is mediated by TNF-alpha and sustained by the IL-33/ST2 axis., PMID:40372523
IL1RAP Expression in Human Atherosclerosis: A Target of Novel Antibodies to Reduce Vascular Inflammation and Adhesion., PMID:40371594
[The immunopathology of asthma]., PMID:40371567
Pre-existing epigenetic state and differential NF-κB activation shape type 2 immune cell responses., PMID:40367949
Inhibition of TRPV1 attenuates innate nasal epithelial responses via NF-κB signaling pathway in allergic rhinitis., PMID:40367690
Microneedles Coated with Cow's Milk Proteins: Immunogenicity, Stability, and Safety Assessment., PMID:40366634
Low IL-35 expression in CSF is associated with Neuro-Behcet Disease: Comparative analysis between parenchymal and Non-parenchymal NBD., PMID:40360083
IL-33 secreted from astrocytes alleviates cognitive impairment associated with neuropathic pain via oxidative stress in mice., PMID:40359065
Biological mechanisms and therapeutic prospects of interleukin-33 in pathogenesis and treatment of allergic disease., PMID:40355878
Therapeutic promise of a sulfated (1 → 4) galactan from edible sea grape Caulerpa racemosa: modulation of cytokine expression in lipopolysaccharide-induced CALU-1 cells., PMID:40354863
IL-33/ST2 drives inflammatory pain via CCL2 signaling and activation of TRPV1 and TRPM8., PMID:40348921
Lingguizhugan decoction inhibit pulmonary hypertension by regulating macrophage IL-6 secretion via IL-33/ST2 pathway., PMID:40347929
Analysis of Rare Coding Variants in 470,000 UK Biobank Participants Reveals Genetic Associations With Childhood Asthma Predisposition., PMID:40342259
Liujunzi Decoction Regulated Intestinal Flora Homeostasis to Relieve Lung-Gut Axis Inflammation in Asthma Flora Disorder Mice: Possibly Related to GATA3/ILC2., PMID:40342036
Cytokines and appetite-regulating hormones in human milk and associations with infant growth across four sites in a longitudinal cohort: The Mothers, Infants and Lactation Quality Study., PMID:40338935
Decreased IL-33 Expression in the Cervix in LPS-Induced Preterm Birth and the Potential Role of Mast Cells: A Murine Model., PMID:40328686
Identification and validation of PARK7 as a novel mitochondria-related signature associated with immune microenvironment in asthma., PMID:40319751
Based on the IL-33/ST2-MyD88 signaling pathway to explore the mechanism of aerobic exercise in antagonizing the inflammatory response in depressive mice., PMID:40319714
Inflammasome signaling in astrocytes modulates hippocampal plasticity., PMID:40318630
Decitabine co-operates with the IL-33/ST2 axis modifying the tumor microenvironment and improving the response to PD-1 blockade in melanoma., PMID:40317004
Eosinophils and pleural macrophages counter regulate IL-33-elicited airway inflammation via the 12/15-lipoxygenase pathway., PMID:40313934
Induction of systemic inflammation by welding fume exposure in office workers as well as welders in welding factories., PMID:40307012
The Role of Eosinophils, Eosinophil-Related Cytokines and AI in Predicting Immunotherapy Efficacy in NSCLC., PMID:40305195
Serum sST2, IL-33, and Hcy Expression in Older Adults Patients with Myocardial Infarction and Their Predictive Value for MACE., PMID:40303845
For research use only. Not for human or drug use.
