Catalog No.
YHA91301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys216-Cys501
Predicted molecular weight
34.93 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60449
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DEC-205, CLEC13B, gp200-MR6, LY75, C-type lectin domain family 13 member B, Ly-75, Lymphocyte antigen 75, CD205
Neutrophils in the Bone Marrow Express DEC205, Guiding Their Migration to Inflamed Tissues., PMID:40467528
Enhanced Cancer Immunotherapy by Bacterial Cytoplasmic Membranes Coated Nanovaccines for Co-Delivery of Ovalbumin Antigen and Immune Adjuvants to Dendritic Cells in Lymph Nodes., PMID:40007905
Antibody-Based Antigen Delivery to Dendritic Cells as a Vaccination Strategy Against Ebola Virus Disease., PMID:39852693
Identification of a novel DEC-205 binding peptide to develop dendritic cell-targeting nanovaccine for cancer immunotherapy., PMID:39067792
Hydatid fluid from Echinococcus granulosus induces autophagy in dendritic cells and promotes polyfunctional T-cell responses., PMID:38817444
Modulation of Dendritic Cell Function via Nanoparticle-Induced Cytosolic Calcium Changes., PMID:38422984
Interaction of human dendritic cell receptor DEC205/CD205 with keratins., PMID:38301891
HOXA3 functions as the on-off switch to regulate the development of hESC-derived third pharyngeal pouch endoderm through EPHB2-mediated Wnt pathway., PMID:38259452
Lipoproteins are key immunostimulatory components of Bacillus species for dendritic cell maturation and activation., PMID:38160652
Targeted delivery of autoantigen to dendritic cells prevents development of spontaneous uveitis., PMID:37727784
Thymocyte Development of Humanized Mice Is Promoted by Interactions with Human-Derived Antigen Presenting Cells upon Immunization., PMID:37511462
Activation of regulatory dendritic cells by Mertk coincides with a temporal wave of apoptosis in neonatal lungs., PMID:37327322
Enhancement of the immune response via the facilitation of dendritic cell maturation by CD-205 Receptor-mediated Long-circling liposomes acting as an antigen and astragalus polysaccharide delivery system., PMID:37126987
Development and characterization of DEC-205 receptor targeted Potentilla anserina L polysaccharide PLGA nanoparticles as an antigen delivery system to enhance in vitro and in vivo immune responses in mice., PMID:36306904
Selenoprotein K Is Essential for the Migration and Phagocytosis of Immature Dendritic Cells., PMID:35883755
PgtE Enzyme of Salmonella enterica Shares the Similar Biological Roles to Plasminogen Activator (Pla) in Interacting With DEC-205 (CD205), and Enhancing Host Dissemination and Infectivity by Yersinia pestis., PMID:35401532
Insufficiency of CD205-positive cortical thymic epithelial cells in immature Japanese Black cattle with severe thymic abnormalities and poor prognosis., PMID:35038635
Nanovaccines silencing IL-10 production at priming phase for boosting immune responses to melanoma., PMID:34419495
Antigen Delivery to DEC205+ Dendritic Cells Induces Immunological Memory and Protective Therapeutic Effects against HPV-Associated Tumors at Different Anatomical Sites., PMID:34345218
The differentiation of new human CD303+ Plasmacytoid dendritic cell subpopulations expressing CD205 and/or CD103 regulated by Non-Small-Cell lung cancer cells., PMID:34298400
Interaction Between SNP Genotype and Efficacy of Anastrozole and Exemestane in Early-Stage Breast Cancer., PMID:34048027
Laser-assisted epicutaneous immunization to target human skin dendritic cells., PMID:33797121
Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo., PMID:33616089
CD205+ polymorphonuclear myeloid-derived suppressor cells suppress antitumor immunity by overexpressing GLUT3., PMID:33368883
Distinct Signatures in the Receptor Repertoire Discriminate CD56bright and CD56dim Natural Killer Cells., PMID:33335526
The cryo-EM structure of the endocytic receptor DEC-205., PMID:33257321
Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets., PMID:35121932
Production of a full chimeric mouse x pig anti-porcine DEC205 receptor recombinant antibody., PMID:33186587
Generating Bovine Monocyte-Derived Dendritic Cells for Experimental and Clinical Applications Using Commercially Available Serum-Free Medium., PMID:33178224
DEC-205 receptor-mediated long-circling nanoliposome as an antigen and Eucommia ulmoides polysaccharide delivery system enhances the immune response via facilitating dendritic cells maturation., PMID:33169636
Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models., PMID:33131247
A CD205-directed antibody drug conjugate - lymphoma precision oncology or sophisticated chemotherapy?, PMID:33131240
Differential expression patterns of glycosphingolipids and C-type lectin receptors on immune cells in absence of functional regulatory T cells., PMID:32737949
LY75 Suppression in Mesenchymal Epithelial Ovarian Cancer Cells Generates a Stable Hybrid EOC Cellular Phenotype, Associated with Enhanced Tumor Initiation, Spreading and Resistance to Treatment in Orthotopic Xenograft Mouse Model., PMID:32679765
Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response., PMID:32591401
B Lymphocytes as Targets of the Immunomodulatory Properties of Human Amniotic Mesenchymal Stromal Cells., PMID:32582218
Langerhans Cells From Mice at Birth Express Endocytic- and Pattern Recognition-Receptors, Migrate to Draining Lymph Nodes Ferrying Antigen and Activate Neonatal T Cells in vivo., PMID:32395120
Immune Checkpoint Inhibition Followed by Tumor Infiltration of Dendritic Cells in Murine Neuro-2a Neuroblastoma., PMID:32380346
Variation in the response of bovine alveolar lavage cells to diverse species of probiotic bacteria., PMID:32178719
LY75 Ablation Mediates Mesenchymal-Epithelial Transition (MET) in Epithelial Ovarian Cancer (EOC) Cells Associated with DNA Methylation Alterations and Suppression of the Wnt/β-Catenin Pathway., PMID:32156068
IL33 activates CD8+T and NK cells through MyD88 pathway to suppress the lung cancer cell growth in mice., PMID:32140881
Ex vivo assessment of in vivo DC-targeted antibodies in pre-clinical models., PMID:32000908
Prolongation of rat-to-mouse islets xenograft survival by co-transplantation of autologous IL-10 differentiated murine tolerogenic dendritic cells., PMID:31984564
Non-small Cell Lung Cancer Cells Modulate the Development of Human CD1c+ Conventional Dendritic Cell Subsets Mediated by CD103 and CD205., PMID:31921114
Theileria annulata transformation altered cell surface molecules expression and endocytic function of monocyte-derived dendritic cells., PMID:31899129
Precision medicine for human cancers with Notch signaling dysregulation (Review)., PMID:31894255
Probiotics ingestion prevents HDAC11-induced DEC205+ dendritic cell dysfunction in night shift nurses., PMID:31784669
Diagnostic utility of CD205 in breast cancer: Simultaneous detection of myoepithelial cells and dendritic cells in breast tissue by CD205., PMID:31524947
Development and Characterization of a Preclinical Model for the Evaluation of CD205-Mediated Antigen Delivery Therapeutics in Type 1 Diabetes., PMID:31356169
CD93 is a cell surface lectin receptor involved in the control of the inflammatory response stimulated by exogenous DNA., PMID:31335975
For research use only. Not for human or drug use.
