Catalog No.
YHA28701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg787-Arg1084
Predicted molecular weight
60.24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14746
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EST2, TCS1, HEST2, Telomerase reverse transcriptase, Telomerase catalytic subunit, Telomerase-associated protein 2, TRT, TP2, TERT
The potential role of PAX5 and PAX8 in regulating telomerase activity: a narrative mini-review., PMID:40515947
The immortality mechanism of TERT promoter mutant cancers is self-reinforcing and reversible., PMID:40513567
Following the fate of polystyrene micro and nanobeads during in vitro digestion., PMID:40503530
Telomere attrition alters extracellular vesicles conferring adverse impacts on neuronal viability and inflammatory response., PMID:40502707
HCV-related hepatocellular carcinoma: gene signatures associated with TERT promoter mutations and sex., PMID:40495193
[Advances in thyroid cytopathology in China over the last ten years: retrospect and prospect]., PMID:40494760
Inhibition of Influenza Entry by Organosilicon Compounds., PMID:40492611
Intratumoral heterogeneity of cancer driver genomic alterations in myxoid liposarcomas., PMID:40489430
TERT/FOXO1 signaling promotes islet β-cell dysfunction in type 2 diabetes mellitus by regulating ATG9A-mediated autophagy., PMID:40487620
Senescence caused by telomerase inactivation in myeloid, mesenchymal, and endothelial cells has distinct effects on cancer progression., PMID:40482194
Oxidative stress-induced decreased expression of FABP5 leads to mitochondrial damage and survival disorder of decidual stromal cells in women with recurrent spontaneous abortion., PMID:40480484
Strategy to overcome a nirmatrelvir resistance mechanism in the SARS-CoV-2 nsp5 protease., PMID:40479048
Mechanism of human α3β GlyR regulation by intracellular M3/M4 loop phosphorylation and 2,6-di-tert-butylphenol interaction., PMID:40473619
TERT translocation as a Novel condition in Intrauterine Growth Restriction rats with early catch-up growth., PMID:40472052
Development of a microarray based telomerase binding assay reveals unusual binding of a cytochalasin derivative., PMID:40467649
Comparative study of rosemary extract, TBHQ, citric acid and their composite antioxidants on the overall quality of peanuts and evaluation of their synergistic antioxidant properties and interaction., PMID:40467212
Bioprospecting potential, metabolic profiling, and molecular docking studies of metabolites from endophytic fungi associated with Teucrium stocksianum., PMID:40464786
Imaging the effects of treatment with TERT and EGFR inhibitors on glioblastoma: An MR study., PMID:40463649
The Thienopyrimidinone Gamhépathiopine Targets the QO Site of Plasmodium falciparum Cytochrome b., PMID:40460517
Rapid diagnosis of adult-type diffuse glioma using a layered scheme., PMID:40457320
Deciphering the role of Hashimoto's Thyroiditis-related key genes in thyroid cancer via detailed in silico analysis followed by the experimental validation., PMID:40450370
TERT promoter methylation predicts overall survival, immune cell infiltration and response to immunotherapy in clear cell renal cell carcinoma., PMID:40448175
Hepatoprotective Effect of Meroterpenoid-Rich Fraction from the Ethanolic Extract of Sargassum sarratifolium on tert-Butyl Hydroperoxide-Induced Mice., PMID:40443236
Azvudine exhibits potent differentiation-inducing effect by targeting the TERT/p21 axis in acute myeloid leukemia., PMID:40435838
GSK-3484862, a DNMT1 degrader, promotes DNMT3B expression in lung cancer cells., PMID:40433167
Rapid diagnosis of TERT promoter mutation using Terahertz absorption spectroscopy in glioblastoma., PMID:40425623
Dedifferentiated Solitary Fibrous Tumor: A Clinicopathologic, Immunohistochemical, and Molecular Characterization of 25 Cases., PMID:40420616
Multiparametric radiomics signature for predicting molecular genotypes in adult-type diffuse gliomas utilizing 18F-FET PET/MRI., PMID:40420017
Telomerase reverse transcriptase degradation via a rationally designed covalent proteolysis targeting chimera., PMID:40412449
HBV sequence integrated to enhancer acting as oncogenic driver epigenetically promotes hepatocellular carcinoma development., PMID:40405227
Associations between pathological features and radioactive iodine-refractory recurrent papillary thyroid carcinoma: with mutation analysis using recurrent samples., PMID:40394531
Analytical and biological assessment of Magnolia champaca L. stem bark: Integrating ATR-FTIR, GC-MS, thrombolytic activity, brine shrimp lethality and molecular docking., PMID:40390495
Study of the C228T mutation of the TERT promoter in thyroid aspirative punctures of IV category of the Bethesda classification., PMID:40379601
Pathological forms of TDP-43 in amyotrophic lateral sclerosis (ALS) promote aberrant telomere elongation., PMID:40379219
Hepatic adenomas in males: Is molecular characterization helpful in guiding its management?, PMID:40379140
Diethyldithiocarbamate-Cu4O3 nanocomplex induced mitochondrial and telomerase dysfunction in non-small cell lung cancer., PMID:40377424
Surrogate matrix approach to quantify endogenous progesterone in a fasting bioequivalence study of soft gelatin capsules in postmenopausal women., PMID:40375399
Role of genomic analysis in the classification of well differentiated hepatocellular lesions., PMID:40374146
Lung transplantation for interstitial lung disease., PMID:40365094
Telomere Maintenance Pathways in Lower-Grade Gliomas: Insights from Genetic Subtypes and Telomere Length Dynamics., PMID:40362411
Sensitivity of Various Indicators in a Mouse Sensitive Skin Model Treatment with 4-tert-Butylcyclohexanol and Pimecrolimus., PMID:40362313
TERT Immunohistochemistry in Thin Melanomas Compared to Melanocytic Nevi., PMID:40361989
In silico identification and structural characterization of telomerase reverse transcriptases in parasitic platyhelminths., PMID:40360013
Radiation-Induced Meningiomas Have an Aggressive Clinical Course: Genetic Signature Is Limited to NF2 Alterations, and Epigenetic Signature Is H3K27me3 Loss., PMID:40359980
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration., PMID:40356987
Comparative analysis of N/TERT-1 and N/TERT-2G keratinocyte responses to oxidative stress and immune challenges., PMID:40355015
Telomeres and Telomerase: Targets for Chemoprevention of Hepatocellular Carcinoma With Bioactive Food Compounds., PMID:40351047
Plasmacytoid urothelial carcinoma of the urinary bladder: A single institution experience with focus on next-generation sequencing (NGS) and PD-L1 immunohistochemistry., PMID:40349989
Genetic re-classification of combined hepatocellular-cholangiocarcinoma and small duct type intrahepatic cholangiocarcinoma., PMID:40349569
Establishment and characterization of Cri Du Chat neuronal stem cells: a novel promising resource to study the syndrome., PMID:40343585
For research use only. Not for human or drug use.
