Anti-Human SEMA3A Polyclonal Antibody

Catalog No.

PHG82801

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SEMA3A (Lys26-His276).

Target

Semaphorin III, Sema III, SEMA3A, Semaphorin-3A, SEMAD

Purification

Purified by antigen affinity column.

Accession

Q14563

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Non-Canonical Wnt16 and microRNA-145 Mediate the Response of Human Bone Marrow Stromal Cells to Additively Manufactured Porous 3-Dimensional Biomimetic Titanium-Aluminum-Vanadium Constructs., PMID:39937002

Wnt16 Increases Bone-to-Implant Contact in an Osteopenic Rat Model by Increasing Proliferation and Regulating the Differentiation of Bone Marrow Stromal Cells., PMID:38517621

Aging does not affect the proportion of taste cell types in mice., PMID:38328800

Paradoxical expression of NRP1 in decidual stromal and immune cells reveals a novel inflammation balancing mechanism during early pregnancy., PMID:37328599

BI-Y, an Neuropilin-1 Antagonist, Enhances Revascularization and Prevents Vascular Endothelial Growth Factor-A Induced Retinal Hyperpermeability in Rodent Models of Retinopathies., PMID:36997325

Efficacy of an Anti-Semaphorin 3A Neutralizing Antibody in a Male Experimental Retinal Vein Occlusion Mouse Model., PMID:35822950

Sema3A Antibody BI-X Prevents Cell Permeability and Cytoskeletal Collapse in HRMECs and Increases Tip Cell Density in Mouse Oxygen-Induced Retinopathy., PMID:35727188

Semaphorin 3A Levels in Lupus with and without Secondary Antiphospholipid Antibody Syndrome and Renal Involvement., PMID:34927690

Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution., PMID:34848712

Silicified collagen scaffold induces semaphorin 3A secretion by sensory nerves to improve in-situ bone regeneration., PMID:34820584

Inhibition of Sema-3A Promotes Cell Migration, Axonal Growth, and Retinal Ganglion Cell Survival., PMID:34817617

Decreased Presence of Mast Cells in the Bursa Premacularis of Proliferative Diabetic Retinopathy., PMID:34515200

Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis., PMID:34083229

Semaphorin3A increases M1-like microglia and retinal ganglion cell apoptosis after optic nerve injury., PMID:34039431

Cleavage of the Perlecan-Semaphorin 3A-Plexin A1-Neuropilin-1 (PSPN) Complex by Matrix Metalloproteinase 7/Matrilysin Triggers Prostate Cancer Cell Dyscohesion and Migration., PMID:33809984

Semaphorin 3A promotes the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells in inflammatory environments by suppressing the Wnt/β-catenin signaling pathway., PMID:33566267

Mesenchymal Stromal Cells Promote Retinal Vascular Repair by Modulating Sema3E and IL-17A in a Model of Ischemic Retinopathy., PMID:33553187

Expression of Semaphorin 3A in Malignant and Normal Bladder Tissue: Immunohistochemistry Staining and Morphometric Evaluation., PMID:33546237

MicroRNA-145 transcriptionally regulates Semaphorin 3A expression in prostate cancer cells., PMID:33501702

Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development., PMID:33266104

Reconsideration of the Semaphorin-3A Binding Motif Found in Chondroitin Sulfate Using Galnac4s-6st-Knockout Mice., PMID:33143303

Semaphorin3A released from human dental pulp cells inhibits the increase in interleukin-6 and CXC chemokine ligand 10 production induced by tumor necrosis factor-α through suppression of nuclear factor-κB activation., PMID:32926524

SEMA3A and IGSF10 Are Novel Contributors to Combined Pituitary Hormone Deficiency (CPHD)., PMID:32612575

Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats., PMID:32408881

Identification and functional study of immortalized mouse thymic epithelial cells., PMID:32107001

Regulation of mesenchymal stem cell differentiation on microstructured titanium surfaces by semaphorin 3A., PMID:32028017

Neuropilin-1 Acts as a Receptor for Complement Split Products., PMID:31572401

Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1., PMID:31350404

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins., PMID:31300520

Semaphorin 3A Inhibits Nerve Regeneration During Early Stage after Inferior Alveolar Nerve Transection., PMID:30862799

Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy., PMID:30679185

Semaphorin 3A inhibits allergic inflammation by regulating immune responses in a mouse model of allergic rhinitis., PMID:30597767

The Neuropilin-1 Ligand, Sema3A, Acts as a Tumor Suppressor in the Pathogenesis of Acute Leukemia., PMID:30378769

A mechanism for semaphorin-induced apoptosis: DNA damage of endothelial and myogenic cells in primary cultures from skeletal muscle., PMID:29854302

miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non-Cell-Autonomous Mechanism in ALS., PMID:29773756

Axonal Guidance Signaling Pathway Is Suppressed in Human Nasal Polyps., PMID:29754498

Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells., PMID:29740048

Pharmacokinetics, Biodistribution, and Toxicity Evaluation of Anti-SEMA3A (F11) in In Vivo Models., PMID:29715102

Wedelolactone inhibits osteoclastogenesis but enhances osteoblastogenesis through altering different semaphorins production., PMID:29702282

Semaphorin3A: A Potential Therapeutic Tool for Lupus Nephritis., PMID:29670620

Expression of circulating Semaphorin3A and its association with inflammation and bone destruction in rheumatoid arthritis., PMID:29656374

Konjac Ceramide (kCer) Regulates NGF-Induced Neurite Outgrowth via the Sema3A Signaling Pathway., PMID:29238028

Anti-SEMA3A Antibody: A Novel Therapeutic Agent to Suppress Glioblastoma Tumor Growth., PMID:29129044

Antibody recognizing 4-sulfated chondroitin sulfate proteoglycans restores memory in tauopathy-induced neurodegeneration., PMID:28890301

SEMA3A partially reverses VEGF effects through binding to neuropilin-1., PMID:28636974

The association between semaphorin 3A levels and gluten-free diet in patients with celiac disease., PMID:28502679

Novel role of semaphorin 3A in the growth and progression of hepatocellular carcinoma., PMID:28498470

[Expression and Clinical Significance of Semaphorin 3A in serum and mononuclear cells in patients with systemic lupus erythematosus]., PMID:28219195

Wedelolactone Enhances Osteoblastogenesis but Inhibits Osteoclastogenesis through Sema3A/NRP1/PlexinA1 Pathway., PMID:27803667

Angiogenesis in the skin of SHARPIN-deficient mice with chronic proliferative dermatitis., PMID:27794420

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