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Recombinant Human CGB1 Protein, N-His

Catalog #:   YHA00901 Specific References (67) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: A6NKQ9
Protein length: Leu55-Pro153
Overview

Catalog No.

YHA00901

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Leu55-Pro153

Predicted molecular weight

12.95 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

A6NKQ9

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

CGB1, Choriogonadotropin subunit beta variant 1

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human CGB1 protein
References

The Study of the Expression of CGB1 and CGB2 in Human Cancer Tissues. PMID: 32957442

Human chorionic gonadotropin beta subunit genes CGB1 and CGB2 are transcriptionally active in ovarian cancer. PMID: 23774837

Novel insights into the expression of CGB1 & 2 genes by epithelial cancer cell lines secreting ectopic free hCGbeta. PMID: 24778026

The evolution and genomic landscape of CGB1 and CGB2 genes. PMID: 17055150

G-protein beta subunit of Cochliobolus heterostrophus involved in virulence, asexual and sexual reproductive ability, and morphogenesis. PMID: 15590838

Fine-scale quantification of HCG beta gene transcription in human trophoblastic and non-malignant non-trophoblastic tissues. PMID: 18048458

Regulation of human chorionic gonadotropin beta subunit expression in ovarian cancer. PMID: 31362717

Expression of beta-subunit of HCG genes during normal and failed pregnancy. PMID: 16123088

Analysis of the human CGB/LHB gene cluster in breast tumors by real-time quantitative RT-PCR assays. PMID: 11368883

Progress in type II dehydroquinase inhibitors: from concept to practice. PMID: 17004270

Genome-wide linkage analysis of chromogranin B expression in the CEPH pedigrees: implications for exocytotic sympathochromaffin secretion in humans. PMID: 15138309

High divergence in primate-specific duplicated regions: human and chimpanzee chorionic gonadotropin beta genes. PMID: 18606016

Methylation status of human chorionic gonadotropin beta subunit promoter and TFAP2A expression as factors regulating CGB gene expression in placenta. PMID: 25063728

Genetic and biochemical characterization of CGB-1, an Ambler class B carbapenem-hydrolyzing beta-lactamase from Chryseobacterium gleum. PMID: 12183230

EBR-1, a novel Ambler subclass B1 beta-lactamase from Empedobacter brevis. PMID: 12234848

Parallel solid-phase synthesis and evaluation of inhibitors of Streptomyces coelicolor type II dehydroquinase. PMID: 14667226

Synthesis of polyhydroxycyclohexanes and relatives from (-)-quinic acid. PMID: 12636388

In Silico Network Toxicology, Molecular Docking, and Multi-Level Bioinformatics Reveal Methyl Eugenol-Induced Hepatocellular Carcinoma Mechanisms in Humans., PMID:40370109

Copper is essential for cyclin B1-mediated CDK1 activation., PMID:40055333

AdipoR1 enhances the radiation resistance via ESR1/CCNB1IP1/cyclin B1 pathway in hepatocellular carcinoma cells., PMID:39849382

Positively charged specificity site in cyclin B1 is essential for mitotic fidelity., PMID:39833154

Forced Vasohibin-1 Expression Increases Paclitaxel Sensitivity of Ovarian Cancer by Inhibiting Microtubule Activity., PMID:39710372

[CEP192 overexpression is correlated with poor prognosis of gastric cancer and promotes gastric cancer cell proliferation by regulating PLK1/CDK1/Cyclin B1 signaling]., PMID:39623269

UHRF1 knockdown induces cell cycle arrest and apoptosis in breast cancer cells through the ZBTB16/ANXA7/Cyclin B1 axis., PMID:39308302

CDK5-cyclin B1 regulates mitotic fidelity., PMID:39232161

The role of GADD45G methylation in endometrial cancer: Insights into CDK1/CCNB1 activation and therapeutic opportunities., PMID:39206984

Spatial control of the APC/C ensures the rapid degradation of cyclin B1., PMID:39143240

The Interaction of Calcium-Sensing Receptor with KIF11 Enhances Cisplatin Resistance in Lung Adenocarcinoma via BRCA1/cyclin B1 pathway., PMID:39113697

eIF6 Promotes Gastric Cancer Proliferation and Invasion by Regulating Cell Cycle., PMID:38987443

Study on the mechanism of quercetin in Sini Decoction Plus Ginseng Soup to inhibit liver cancer and HBV virus replication through CDK1., PMID:38858165

Hsa-circ-0006091 modulates the proliferation of hepatocellular carcinoma via the miR-622/CCNB1 axis., PMID:38813026

Enrichment for the POLE mutated against p53 wild subtype using clinicopathologic factors and cyclin B1 immunohistochemistry in endometrial cancer., PMID:38764327

Serum/glucocorticoid-regulated kinase 1 contributes to the proliferation of varicella-zoster virus and induction of cyclin B1 expression., PMID:38722402

KIF22 promotes multiple myeloma progression by regulating the CDC25C/CDK1/cyclinB1 pathway., PMID:38713252

Cyclin B1: A potential prognostic and immunological biomarker in pan-cancer., PMID:38581717

Bioinformatics analysis highlights CCNB1 as a potential prognostic biomarker and an anti-kidney renal papillary cell carcinoma drug target., PMID:38518000

Identification of Hub genes with prognostic values in colorectal cancer by integrated bioinformatics analysis., PMID:38393891

Prognostic value of cyclin B1 and cyclin B2 expression in breast cancer: A systematic review and updated meta-analysis., PMID:38241547

BubR1 and cyclin B1 immunoexpression in pleomorphic adenoma and polymorphous adenocarcinoma of minor salivary glands., PMID:38043194

Role of CCNB1, CENPF, and neutrophils in lung cancer diagnosis and prognosis., PMID:37986322

DEPDC1B enhances malignant phenotypes of multiple myeloma through upregulating CCNB1 and inhibiting p53 signaling pathway., PMID:37979396

Resveratrol affects ccRCC cell senescence and macrophage polarization by regulating the stability of CCNB1 by RBM15., PMID:37909116

Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability., PMID:37839786

KCNN1 promotes proliferation and metastasis of breast cancer via ERLIN2-mediated stabilization and K63-dependent ubiquitination of Cyclin B1., PMID:37831636

A pancancer analysis of the oncogenic role of cyclin B1 (CCNB1) in human tumors., PMID:37758792

CCNB1 is a novel prognostic biomarker and promotes proliferation, migration and invasion in Wilms tumor., PMID:37592341

MicroRNA-30c-5p arrests bladder cancer G2/M phase and suppresses its progression by targeting PRC1-mediated blocking of CDK1/Cyclin B1 axis., PMID:37532136

The role of CXCL8 and CCNB1 in predicting hepatocellular carcinoma in the context of cirrhosis: implications for early detection and immune-based therapies., PMID:37391641

Expression significance of Emi1, UBCH10 and CyclinB1 in esophageal squamous cell carcinoma., PMID:37168048

CCNB1 and AURKA are critical genes for prostate cancer progression and castration-resistant prostate cancer resistant to vinblastine., PMID:36601001

miR-144 negatively regulates the effect of CCNB1 protein on the biological behavior of hepatoma cells., PMID:36495514

The clinical significance of cyclin B1 (CCNB1) in invasive breast cancer with emphasis on its contribution to lymphovascular invasion development., PMID:36418517

Identification and verification of CCNB1 as a potential prognostic biomarker by comprehensive analysis., PMID:36167975

High expression of CCNB1 driven by ncRNAs is associated with a poor prognosis and tumor immune infiltration in breast cancer., PMID:36040381

CCNB1 and CCNB2 involvement in the pathogenesis of psoriasis: a bioinformatics study., PMID:35949173

Expression of KIF2A, NDC80, CDK1, and CCNB1 in breast cancer patients: Their interaction and linkage with tumor features and prognosis., PMID:35949045

Small changes in phospho-occupancy at the kinetochore-microtubule interface drive mitotic fidelity., PMID:35878017

The intercorrelation among CCT6A, CDC20, CCNB1, and PLK1 expressions and their clinical value in papillary thyroid carcinoma prognostication., PMID:35838025

Circ-CCNB1 Modulates Trophoblast Proliferation and Invasion in Spontaneous Abortion by Regulating miR-223/SIAH1 axis., PMID:35731831

CircPVT1 promotes the tumorigenesis and metastasis of osteosarcoma via mediation of miR-26b-5p/CCNB1 axis., PMID:35648221

Circular RNA circCCNB1 inhibits the migration and invasion of nasopharyngeal carcinoma through binding and stabilizing TJP1 mRNA., PMID:35471687

Bioinformatics Analysis Highlight Differentially Expressed CCNB1 and PLK1 Genes as Potential Anti-Breast Cancer Drug Targets and Prognostic Markers., PMID:35456460

CCNB1, Negatively Regulated by miR-559, Promotes the Proliferation, Migration, and Invasion of Ovarian Carcinoma Cells., PMID:35262876

MiR-139-5p Targeting CCNB1 Modulates Proliferation, Migration, Invasion and Cell Cycle in Lung Adenocarcinoma., PMID:35181869

[EEFSEC knockdown inhibits proliferation, migration and invasion of prostate cancer cells in vitro]., PMID:35012909

CircCCNB1 silencing acting as a miR-106b-5p sponge inhibited GPM6A expression to promote HCC progression by enhancing DYNC1I1 expression and activating the AKT/ERK signaling pathway., PMID:35002514

An Oxidative Stress-Related Gene Pair (CCNB1/PKD1), Competitive Endogenous RNAs, and Immune-Infiltration Patterns Potentially Regulate Intervertebral Disc Degeneration Development., PMID:34858418

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human CGB1 Protein, N-His [YHA00901]
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