Catalog No.
DHD37701
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Target
Kallikrein-2, Tissue kallikrein-2, KLK2, hGK-1, Glandular kallikrein-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P20151
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
JNJ-69086420, JNJ 69086420, JNJ69086420
Clone ID
JNJ-69086420
Pasritamig, a First-in-Class, Bispecific T-Cell Engager Targeting Human Kallikrein 2, in Metastatic Castration-Resistant Prostate Cancer: A Phase I Study., PMID:40450573
Developmental Therapeutics in Metastatic Prostate Cancer: New Targets and New Strategies., PMID:39272956
A Phase 0 Study to Assess the Biodistribution and Pharmacokinetics of a Radiolabeled Antibody Targeting Human Kallikrein 2 in Participants with Metastatic Castration-Resistant Prostate Cancer., PMID:38782459
Genomic and Immunologic Correlates in Prostate Cancer with High Expression of KLK2., PMID:38396898
Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy., PMID:32532924
Molecular profiling of radical prostatectomy tissue from patients with no sign of progression identifies ERG as the strongest independent predictor of recurrence., PMID:31741711
Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer., PMID:29691406
Preclinical imaging of kallikrein-related peptidase 2 (hK2) in prostate cancer with a (111)In-radiolabelled monoclonal antibody, 11B6., PMID:26116115
Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome., PMID:25649018
Tickling stimulation causes the up-regulation of the kallikrein family in the submandibular gland of the rat., PMID:22982067
Comparative biomarker expression and RNA integrity in biospecimens derived from radical retropubic and robot-assisted laparoscopic prostatectomies., PMID:20615888
Immunoreactivity of recombinant human glandular kallikrein using monoclonal antibodies raised against prostate-specific antigen., PMID:9140120
For research use only. Not for human or drug use.
