Catalog No.
DHC83108
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Target
Mast/stem cell growth factor receptor Kit, p145 c-kit, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, KIT, PBT, Piebald trait protein, Proto-oncogene c-Kit, SCFR, CD117
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P10721
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
CDX-0158, CDX0158, CDX 0158
Clone ID
CDX-0158
Effects of C3aR activated mast cells in eosinophilic esophagitis., PMID:40502038
The cytotoxic effect of quercetin-induced apoptosis on lung metastatic cells from giant cell tumor of bone., PMID:40418557
Targeting KIT With Antibody-Drug Conjugates in Chromophobe Renal Cell Carcinoma., PMID:40408838
Navigating Ongoing Challenges in GI Stromal Tumors., PMID:40393024
Pathology Seen in Myenteric Plexus in Two Subjects With Waardenburg Syndrome., PMID:40364458
Multiplex immunophenotyping of human acute myeloid leukemia patients revealed single -cell heterogeneity with special attention on therapy sensitive and therapy resistant subpopulations., PMID:40313947
Functional roles of interstitial cells of Cajal in the GI tract of rats., PMID:40235202
[Indolent systemic mastocytosis : an overview in 2025]., PMID:40176613
Cold-induced anaphylaxis: new insights into clinical and genetic characteristics., PMID:40061949
First Report of Pembrolizumab Activity in KIT-Mutated Thymic Carcinoma., PMID:39996868
Immunohistochemical analysis of 147 cases of low-grade endometrial stromal sarcoma: refining the immunohistochemical profile of LG-ESS on a large, molecularly confirmed series., PMID:39836188
Histologic, histochemical, and immunohistochemical changes in buffalo liver with cystic echinococcosis., PMID:39757763
KIRA6 is an Effective and Versatile Mast Cell Inhibitor of IgE-mediated Activation., PMID:39676406
Mechanisms of reduced sensitization by extensive hydrolysis of milk protein concentrate: Impact on the immune response of Th1/Th2 and Treg/Th17 cells in mice., PMID:39662801
An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA., PMID:39656107
Gene Expression Profiling of the Peritumoral Immune Cell Infiltrate of Penile Squamous Cell Carcinomas., PMID:39596210
A single-chain variable fragment-based bispecific T-cell activating antibody against CD117 enables T-cell mediated lysis of acute myeloid leukemia and hematopoietic stem and progenitor cells., PMID:39564539
Novel Insights Into the Ultrastructural and Immunofluorescence Characteristics of Limb Skin in the Red-Eared Slider Turtle (Trachemys scripta elegans)., PMID:39508632
Investigating the effect of immunomagnetic separation on the immunophenotype and viability of plasma cells in plasma cell disorders., PMID:39493694
Targeted hematopoietic stem cell depletion through SCF-blockade., PMID:39473008
Gastrointestinal Stromal Tumors: Variants and Some Pitfalls That They Create., PMID:39466697
Role of Interstitial Cells of Cajal in Congenital Ureteropelvic Junction Obstruction., PMID:39316030
Immunohistochemical Analysis of CD117 in the Mast Cells of Odontogenic Keratocysts., PMID:39310512
C-Kit Immunohistochemical Expression as a Complementary Method to Assess Mast Cell Density in Helicobacter pylori-Mediated Gastritis., PMID:39278202
A significant difference of synovial mast cells in synovium from rotator cuff arthropathy compared to rotator cuff tears: A histological pilot study., PMID:39156865
NOTCH1- and CD117-Positive Stem Cells in Human Endometriosis and Adenomyosis Lesions., PMID:39125516
The prognostic significance of CD117-positive mast cells and microvessel density in colorectal cancer., PMID:39029054
Unusual PEComa With PRCC :: TFE3 Fusion Mimicking Sinonasal Tract Melanoma., PMID:38975712
Clinicopathological differences between T-lymphoblastic leukemia/lymphoma, early T-precursor lymphoblastic leukemia/lymphoma, and mixed-phenotype acute leukemia with T lineage: An analysis of 41 adult cases., PMID:38945375
An optimized method for IgE-mediated degranulation of human lung mast cells., PMID:38881896
Measurable Residual Disease Analysis by Flow Cytometry and Correlation With Molecular Measurable Residual Disease in Acute Promyelocytic Leukemia: A Real-World Prospective Study., PMID:38838353
Usefulness of antibody-drug conjugate as preconditioning for hematopoietic stem cell-targeted gene therapy in wild-type and Fabry disease mouse models., PMID:38820907
Flow cytometric immunophenotypic differentiation patterns of bone marrow eosinophilopoiesis., PMID:38666394
Lin-CD117+CD34+FcεRI+ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti-IgE therapy., PMID:38634175
Clinical, Epidemiological, Morphological, and Immunohistochemical Aspects of Nasopharyngeal Carcinoma-4-Year Retrospective Study in the Western Part of Romania., PMID:38611634
Hematopoiesis after anti-CD117 monoclonal antibody treatment in the settings of wild-type and Fanconi anemia mice., PMID:38572555
Immunophenotypic characterization of leukemic stem cells in acute myeloid leukemia using single tube 10-colour panel by multiparametric flow cytometry: Deciphering the spectrum, complexity and immunophenotypic heterogeneity., PMID:38456256
Myxoma Virus Combination Therapy Enhances Lenalidomide and Bortezomib Treatments for Multiple Myeloma., PMID:38251379
Regulation of mast cells by overlapping but distinct protein interactions of Siglec-6 and Siglec-8., PMID:38186079
Development of a flow cytometric panel to assess prognostic biomarkers in fine needle aspirates of canine cutaneous or subcutaneous mast cell tumors., PMID:38076567
Higher PD-1/Tim-3 expression on IFN-γ+ T cells is associated with poor prognosis in patients with acute myeloid leukemia., PMID:37962843
Comparison of Mast Cell Density and Prognostic Factors in Invasive Breast Carcinoma: A Single-Centre Study in Malaysia., PMID:37928785
Diagnostic Utility of EMA, Vimentin and CD117 Immunohistochemical Markers in Subtyping Renal Cell Carcinoma in a Nigerian Tertiary Hospital: A 10-year Retrospective Study., PMID:37906498
Antibody-Based and Cell Therapies for Advanced Mastocytosis: Established and Novel Concepts., PMID:37894806
[Morphological and molecular portrait hybrid renal tumors]., PMID:37850290
Fertility-preserving myeloablative conditioning using single-dose CD117 antibody-drug conjugate in a rhesus gene therapy model., PMID:37828021
Twenty-four-color full spectrum flow cytometry panel for minimal residual disease detection in acute myeloid leukemia., PMID:37533738
Further explorations into the role of mast cells in deaths associated with fatal asphyxia: an immunohistochemical study utilizing CD 117 marker., PMID:37478731
Clinical and Laboratory Characteristics of IgM Primary Plasma Cell Leukemia., PMID:37436385
Ureteropelvic junction obstruction in children by polar vessels: histological examination result., PMID:37254943
For research use only. Not for human or drug use.
