Catalog No.
DHB89904
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Target
C3, ASP, Complement C3, C3adesArg, C3bc, CPAMD1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01024
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
NGM621, NGM 621, NGM-621
Clone ID
NGM621
A case report and literature review on new-onset systemic lupus erythematosus leading to thrombocytopenia in a hemodialysis patient., PMID:40527778
Immunotherapy Platform That Conjugates Antigen to Complement C3-Targeted Liposomes Induces a Robust Adaptive Immune Response., PMID:40507796
An Unusual Presentation of Bullous Skin Lesions During Pregnancy., PMID:40503690
Effects of C3aR activated mast cells in eosinophilic esophagitis., PMID:40502038
A Rare Case of Warm Autoimmune Hemolytic Anemia With Intravascular Hemolysis: A Case Report., PMID:40497195
Primary Sjögren's syndrome presenting with non-diffuse membranoproliferative glomerulonephritis-like lesions in cryoglobulinemic glomerulonephritis: a case report., PMID:40491909
Elevated eosinophil-to-lymphocyte ratio (ELR) as a predictor of relapse for IgG4-related disease: a retrospective study across a decade., PMID:40488799
[Diagnosis, treatment, and genetic analysis of five cases of primary atypical hemolytic uremic syndrome]., PMID:40484823
Clinical and immunopathological assessment of the oral mucosa in coeliac disease: a pilot study., PMID:40483462
Complement in anti-glomerular basement membrane glomerulonephritis., PMID:40469278
Analysis of human factor H-related gene and protein expressed in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation., PMID:40467630
Monoclonal antibodies targeting Candida disrupt biofilms and inhibit growth across global clinical isolates., PMID:40458186
Streptococcus suis AdcA interacts with factor H and inhibits C3b deposition on the bacteria to participate in complement evasion., PMID:40446560
Hemolytic uremic syndrome in severe acute pancreatitis., PMID:40443860
Host complement C3 promotes malaria transmission by killing symbiotic bacteria in the mosquito midgut., PMID:40434644
Activated Immune and Complement C3 Are Potential Contributors in MASH via Stimulating Neutrophil Extracellular Traps., PMID:40422243
Associations between biological markers and haematological manifestations in patients with systemic lupus erythematosus., PMID:40414271
Diagnostic value of blood coagulation index in obstetric antiphospholipid syndrome and its subtypes., PMID:40409231
TLR7 responses in glomerular macrophages accelerate the progression of glomerulonephritis in NZBWF1 mice., PMID:40401698
Expanding the spectrum of genetic causes of DNA-specific exonuclease TREX1 variants in thrombotic microangiopathy., PMID:40383229
The 4 functional segments of Factor H: Role in physiological target recognition and contribution to disease., PMID:40356067
Advancements in Complement Inhibition for PNH and Primary Complement Mediated Thrombotic Microangiopathy., PMID:40354320
Umbilical cord mesenchymal stem cell-derived secretome as a potential treatment for systemic lupus erythematosus: A double-blind randomized controlled trial., PMID:40352183
Transfer of SARS-CoV-2 nucleocapsid protein to uninfected epithelial cells induces antibody-mediated complement deposition., PMID:40343796
Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis., PMID:40338657
The correlation between serum complement levels and clinical presentation in Egyptian immune thrombocytopenia patients., PMID:40327196
Clinical characterization of malignant lymphoma mimicking IgG4-related disease., PMID:40327158
Pregnancy-related Thrombotic Microangiopathy has a spectrum of underlying causes., PMID:40306205
Neutrophil Z Is a Novel Marker to Differentiate Disease Flares From Bacterial Infections in Febrile SLE Patients., PMID:40302194
Complement dysregulation at lymphatics., PMID:40300720
The application of direct immunofluorescence in the pathological diagnosis of oral mucosal diseases: Series of 116 cases., PMID:40300523
B lymphocyte subset-based stratification in primary Sjögren's syndrome: implications for lymphoma risk and personalized treatment., PMID:40295463
Correlation of anti-phosphatidylethanolamine antibodies with premature birth in women with a history of miscarriage: a retrospective study., PMID:40288804
The Clinical and Laboratory Landscape of COVID-19 During the Initial Period of the Pandemic and at the Beginning of the Omicron Era., PMID:40284924
C3-Liposome Delivery of MUC1 Peptide and TLR Agonists Enhances Adaptive Immunity and Results in Sex-Based Tumor Growth Differences., PMID:40284463
Long-term GABA supplementation mitigates anxiety by modulating complement and neuroinflammatory pathways., PMID:40274802
Improved immunocompatibility of active targeting liposomes by attenuating nucleophilic attack of cyclic RGD peptides on complement 3., PMID:40267598
Protection Against Pneumonia Induced by Vaccination with Fimbriae Subunits from Klebsiella pneumoniae., PMID:40266206
The Relationship of Platelets With the Clinical Manifestations and Serologic Markers in Systemic Lupus Erythematosus: A Single-Center Retrospective Study., PMID:40265572
Complete Resolution of Atypical Paraneoplastic Pemphigus Following Treatment With Dupilumab., PMID:40264631
An inactivated bivalent vaccine effectively protects Carassius auratus against Aeromonas caviae and Aeromonas veronii., PMID:40258818
[Efficacy of iptacopan monotherapy for suboptimal response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria]., PMID:40237732
Complement C3 Deficiency Enhances Renal Leptospiral Load and Inflammation While Impairing T Cell Differentiation During Chronic Leptospira interrogans Infection., PMID:40236016
Clinical Features and Treatment of Antibody-Mediated Rejection After Liver Transplantation: A Largest Single Center Experience in China., PMID:40231337
Clinical characteristics and immunotherapy efficacy in autoimmune-associated benign epilepsy with centrotemporal spikes: A prospective cohort study., PMID:40209515
Complement updates in optic neuritis., PMID:40206291
4D label-free quantitative proteomic and phosphoproteomic profiling of the kidney in rat models of antimyeloperoxidase-associated vasculitis., PMID:40201969
Production and Functional Verification of 8-Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-Edited Donor Pigs for Xenotransplantation., PMID:40190036
Serum ferritin is a superior biomarker for evaluating disease activity and kidney injury compared with C-reactive protein in anti-neutrophil cytoplasmic antibody-associated vasculitis., PMID:40172815
Direct immunofluorescence of labial gland in diagnosis of Sjögren's disease., PMID:40172814
For research use only. Not for human or drug use.
