Catalog No.
DHH72426
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Humanized
Isotype
IgG4-kappa fused with Human TGFBR2
Target
VSTM3, TIGIT, V-set and transmembrane domain-containing protein 3, VSIG9, V-set and immunoglobulin domain-containing protein 9, T-cell immunoreceptor with Ig and ITIM domains, TGFR-2, TbetaR-II, TGF-beta type II receptor, TGFBR2, TGF-beta receptor type-2, TGF-beta receptor type II, Transforming growth factor-beta receptor type II
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q495A1 & P37173
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
CAS: 2769742-99-4
Clone ID
Lucorafusp Alfa
Rash associated with antibiotic administration in patients with infectious mononucleosis: a systematic review and meta-analysis., PMID:40512251
Integrative Analysis of Drug Co-Prescriptions in Peritoneal Dialysis Reveals Molecular Targets and Novel Strategies for Intervention., PMID:40507495
International Fibrolamellar Cancer Registry: Opportunities and Challenges., PMID:40499052
Rare types of alpha-1-antitrypsin deficency in the same family: Pi*Mmalton and Pi*Plowell., PMID:40497812
Persistent Atelectasis Prevalence and Incidence in Pediatric Critical Care., PMID:40497177
Validation of a handheld electrocardiogram 6 lead recorder to obtain chest lead equivalents: An Africa Heart Rhythm Association study., PMID:40496591
GX-I7, a long-acting IL-7, safely and effectively increased peripheral CD8+/CD4+ T cells and TILs in patients with locally advanced or metastatic solid tumours., PMID:40490502
Exploring Antimalarial Activity of Drugs using Weighted Atomic Vectors and Artificial Intelligence., PMID:40485561
Efimosfermin alfa (BOS-580), a long-acting FGF21 analogue, in participants with phenotypic metabolic dysfunction-associated steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2a trial., PMID:40484014
Enzyme replacement therapies in adults with Pompe disease: from trials to real-world data., PMID:40471681
Safety, pharmacokinetics and pharmacodynamics of Efsubaglutide Alfa in healthy participants: A randomised, dose-escalation phase 1 study., PMID:40470753
Successful treatment of hairy cell leukaemia with pegylated interferon-alpha-2A., PMID:40469412
Therapeutic efficacy of budesonide suspension combined with poractant alfa injection for neonatal respiratory distress syndrome and its effect on serum ferritin and PAI-1 expressions., PMID:40469168
Italian guidelines for the diagnosis and management of gastro-esophageal reflux disease: Joint consensus from the Italian Societies of: Gastroenterology and Endoscopy (SIGE), Neurogastroenterology and Motility (SINGEM), Hospital Gastroenterologists and Endoscopists (AIGO), Digestive Endoscopy (SIED), and General Medicine (SIMG)., PMID:40450492
The Mini-COMET Clinical Trial: Safety and Efficacy of Avalglucosidase Alfa after 97 Weeks of Treatment in Children with Infantile-Onset Pompe Disease Previously Treated with Alglucosidase Alfa., PMID:40449831
Preclinical Safety., PMID:40445826
Mean Corpuscular Volume Is Not a Reliable Predictor of Iron Deficiency in Patients With Chronic Kidney Disease: A Post-Hoc Analysis of the BRIGHTEN Trial., PMID:40443639
Mobility and Quality of Life in Children with Paediatric-Onset Hypophosphatasia Treated with Asfotase Alfa: Results from UK Managed Access Agreement., PMID:40439960
Less Invasive Surfactant Administration (LISA) versus Intubation Surfactant Extubation (InSurE) technique using higher volume surfactant in management of neonates with respiratory distress syndrome: an open-label randomized controlled trial., PMID:40439732
Life-Threatening Pharyngolaryngeal Hematoma in a Patient With Hemophilia A., PMID:40438813
Global Variation in Lipoprotein(a) Levels Among Patients With Coronary Heart Disease: Insights From the INTERASPIRE Study and Implications for Emerging Lp(a)-Lowering Therapies., PMID:40436467
Multistrain Probiotics Plus Vitamin D Improve Gut Barrier Function and Gut Microbiota Composition in Irritable Bowel Syndrome Without Constipation: Results from a Double-Blind, Randomized, Placebo-Controlled Trial., PMID:40431448
Exploring Multivalent Architectures for Binding and Stabilization of N-Acetylgalactosamine 6-Sulfatase., PMID:40430394
Current status of the immunogenicity of enzyme replacement therapy in fabry disease., PMID:40420145
Phenotypic and Genotypic Spectrum of Indian Patients with Hypophosphatasia., PMID:40416455
Therapeutic adherence in inflammatory bowel disease: User guide from a multidisciplinary modified Delphi consensus., PMID:40414777
[Acid sphingomyelinase deficiency: A review]., PMID:40414757
A global comparison of hepatitis B & C drug pricing., PMID:40414600
Fosfomycin for the treatment of patients with bacterial prostatitis: a systematic review., PMID:40410452
Markedly discordant hypophosphatasia in a young girl., PMID:40409424
A Theoretical and Experimental Study of Carbonized Lignin from Alfa Fibers as a Clay-Based Adsorbent., PMID:40402651
Robust longitudinal neuropsychological norms in Spanish individuals with nonpathological Alzheimer's disease biomarkers., PMID:40402619
Development and description of a porcine model of combat casualty care for traumatic-hemorrhagic shock research and medical training., PMID:40402209
Reversal of anticoagulation in patients with intracerebral haemorrhage related to oral anticoagulants: State of the evidence., PMID:40401655
Effects of erythropoietin on cardiac morphometry in exercised male and female adolescent rats., PMID:40400735
Good clinical practice recommendations for the diagnosis and treatment of functional dyspepsia: An expert review from the Asociación Mexicana de Gastroenterología., PMID:40399175
Defining clinically meaningful thresholds for forced vital capacity in patients with neuromuscular disorders: Lessons learned from the COMET study in Pompe disease., PMID:40397025
Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer, a study with 5-year follow-up: a plain language summary., PMID:40396643
Case of Gynandroblastoma of the Ovary with Raised AFP and Associated DICER 1 Mutation., PMID:40390890
Recurrence risk factors for chronic hepatitis B virus-infected patients who achieve functional cure with pegylated interferon-α-2b-based therapy: a multicenter pilot study., PMID:40390028
SGLT2 inhibitor with and without ALDosterone AntagonIst for heart failure with preserved ejection fraction: Design paper., PMID:40388563
Assisting the Diagnosis of Cirrhosis in Chronic Hepatitis C Patients Based on Machine Learning Algorithms: A Novel Non-Invasive Approach., PMID:40384539
Immune-mediated adverse events and overall survival with tremelimumab plus durvalumab and durvalumab monotherapy in unresectable hepatocellular carcinoma: HIMALAYA phase 3 randomized clinical trial., PMID:40384092
Real-world experience with the diagnosis of bile acid malabsorption (BAM) using serum 7-alpha-C4 and 48-hour stool bile acids., PMID:40383704
Venous thromboembolism in professional drivers of automatic transmission vehicles: an underestimated occupational risk?, PMID:40382788
Author's reply: "Comment on "Italian validation of the IBD-disk tool for the assessment of disability in inflammatory bowel diseases""., PMID:40379540
Long-Term Transfusion Independence with Luspatercept Versus Epoetin Alfa in Erythropoiesis-Stimulating Agent-Naive, Lower-Risk Myelodysplastic Syndromes in the COMMANDS Trial., PMID:40377899
Correction: Long-term safety and efficacy of ropeginterferon alfa-2b in Japanese patients with polycythemia vera., PMID:40377864
HBV-specific T-cell function is nonenhanced by tenofovir-induced decline in HBV viremia or HBsAg titer in chronic hepatitis B., PMID:40377525
Immune-Related Adverse Events Are Associated With Improved Outcomes After Immune Checkpoint Inhibitor Treatment in Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis., PMID:40377239
For research use only. Not for human or drug use.
