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Research Grade Levilimab

Catalog #:   DHC36903 Specific References (12) DATASHEET
Host species: Humanized
Isotype: IgG1-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHC36903

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

sIL6R, Interleukin-6 receptor subunit alpha, CD126, IL-6R 1, IL-6R subunit alpha, Membrane glycoprotein 80, gp80, IL6R, IL-6RA, IL-6 receptor subunit alpha, IL-6R-alpha

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P08887

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

BCD-089, CAS: 2035008-70-7

Clone ID

Levilimab

Data Image
  • Bioactivity
    Detects Human CD126/IL6R/IL-6RA in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Levilimab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Antibodies to watch in 2021, PMID: 33459118

Interleukin-6 blocking agents for treating COVID-19: a living systematic review, PMID: 33734435

Efficacy and Safety of Levilimab in Combination with Methotrexate in Patients with Active Rheumatoid Arthritis: 56-Week Results of Phase III Randomized Double-Blind Placebo-Controlled Trial SOLAR., PMID:39196526

[Efficacy and safety of levilimab in the treatment of patients with rheumatoid arthritis]., PMID:39106512

Interleukin-6 blocking agents for treating COVID-19: a living systematic review., PMID:37260086

[Clinical cases of complicated diverticulitis against the background of severe course COVID-19. Case report]., PMID:37167171

Efficacy of synthetic and biological DMARDs: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis., PMID:36368906

[Experience of anticipatory therapy with IL-6 receptor inhibitors and perspectives for its use in the evolution of COVID-19]., PMID:36286985

[Levilimab and baricitinib prescribing experience in outpatient COVID-19 patients' treatment]., PMID:36286967

The efficacy and safety of levilimab in severely ill COVID-19 patients not requiring mechanical ventilation: results of a multicenter randomized double-blind placebo-controlled phase III CORONA clinical study., PMID:34586459

Interleukin-6 blocking agents for treating COVID-19: a living systematic review., PMID:33734435

Antibodies to watch in 2021., PMID:33459118

Datasheet

Document Download

Research Grade Levilimab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Levilimab [DHC36903]
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