Catalog No.
RVV03004
Species reactivity
Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979)(HBV-D)
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen, S
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03138
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
F124
Both middle and large envelope proteins can mediate neutralization of hepatitis B virus infectivity by anti-preS2 antibodies: escape by naturally occurring preS2 deletions., PMID:39078152
Hybrid large hepatitis B surface protein composed of two viral genotypes C and D induces strongly cross-neutralizing antibodies., PMID:37739886
Identification of neutralizing epitopes in the preS2 domain of the hepatitis B virus., PMID:36511290
Serum O-glycosylated hepatitis B surface antigen levels in patients with chronic hepatitis B during nucleos(t)ide analog therapy., PMID:35641912
5' preS1 Mutations To Prevent Large Envelope Protein Expression from Hepatitis B Virus Genotype A or Genotype D Markedly Increase Polymerase-Envelope Fusion Protein., PMID:35019714
The Variability of Amino Acid Sequences in Hepatitis B Virus., PMID:30610573
Genetic variability in coding regions of the surface antigen and reverse transcriptase domain of hepatitis B virus polymerase, Colombia, 2002-2014., PMID:30184362
Quantification of large and middle proteins of hepatitis B virus surface antigen (HBsAg) as a novel tool for the identification of inactive HBV carriers., PMID:28951526
Sequence analysis and functional characterization of full-length hepatitis B virus genomes from Korean cirrhotic patients with or without liver cancer., PMID:28373061
Immunotherapy With the PreS-based Grass Pollen Allergy Vaccine BM32 Induces Antibody Responses Protecting Against Hepatitis B Infection., PMID:27568223
Applications of human hepatitis B virus preS domain in bio- and nanotechnology., PMID:26139986
Cationic lipid-formulated DNA vaccine against hepatitis B virus: immunogenicity of MIDGE-Th1 vectors encoding small and large surface antigen in comparison to a licensed protein vaccine., PMID:24992038
Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis B virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients., PMID:23172669
Identification of the critical regions in hepatitis B virus preS required for its stability., PMID:17918766
Immunoadhesins containing pre-S domains of hepatitis B virus large envelope protein are secreted and inhibit virus infection., PMID:17329331
Optimisation of secretion of recombinant HBsAg virus-like particles: Impact on the development of HIV-1/HBV bivalent vaccines., PMID:17005303
Polyhydroxyalkanoate chip for the specific immobilization of recombinant proteins and its applications in immunodiagnostics., PMID:32218672
Immunogenicity of a hepatitis B DNA vaccine administered to chronic HBV carriers., PMID:16310901
Expression and purification of the complete PreS region of hepatitis B Virus., PMID:15918190
Mosaic hepatitis B virus core particles presenting the complete preS sequence of the viral envelope on their surface., PMID:15302960
Pre-s1 antigen-dependent infection of Tupaia hepatocyte cultures with human hepatitis B virus., PMID:12915565
The PreS2 activator MHBs(t) of hepatitis B virus activates c-raf-1/Erk2 signaling in transgenic mice., PMID:11847101
Hepatitis B virus genomic sequence in the circulation of hepatocellular carcinoma patients: comparative analysis of 40 full-length isolates., PMID:9930189
A comparative trial of two surface subunit recombinant hepatitis B vaccines vs a surface and PreS subunit vaccine for immunization of healthy adults., PMID:9751013
Hepatitis B vaccine containing surface antigen and selected preS1 and preS2 sequences. 1. Safety and immunogenicity in young, healthy adults., PMID:9364674
Definition of the primary structure of hepatitis B virus (HBV) pre-S hepatocyte binding domain using random peptide libraries., PMID:9356343
Protease-induced infectivity of hepatitis B virus for a human hepatoblastoma cell line., PMID:8642654
[Anti-idiotypic antibodies against antibodies to HBsAg and against antibodies to pre-S1 and pre-S2 fragments of HBV in patients with chronic HBs antigenemia]., PMID:8926772
DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans., PMID:7777503
Quantitative assessment of IgM antibodies towards an immunodominant B-cell epitope within the preS2 domain of HBV in the natural course and during combined prednisone/interferon alpha 2b treatment of chronic hepatitis B virus infection., PMID:7636501
Fibronectin of human liver sinusoids binds hepatitis B virus: identification by an anti-idiotypic antibody bearing the internal image of the pre-S2 domain., PMID:7815551
[Epitopes of the envelope of the hepatitis B virus: a structural approach]., PMID:7536913
Hepatitis B virus (HBV) binding factor in human serum: candidate for a soluble form of hepatocyte HBV receptor., PMID:8510225
Complete nucleotide sequence and viral envelope protein expression of a hepatitis B virus DNA derived from a hepatitis B surface antigen-seronegative patient., PMID:8409340
Identification of polymerized-albumin receptor domain in the pre-S2 region of hepatitis B virus surface antigen M protein., PMID:1369362
Production of infectious hepatitis delta virus in vitro and neutralization with antibodies directed against hepatitis B virus pre-S antigens., PMID:1309901
Detection of antibody to the PreS2 sequence of the hepatitis B virus envelope protein using an immuno-ligand assay with a silicon sensor detection system., PMID:1765651
Mapping of linear B-cell epitopes of hepatitis B surface antigen., PMID:1725062
Cloning, expression, isolation and characterization of the pre-S domains of hepatitis B surface antigen, devoid of the S protein., PMID:2049071
Synthesis and immunogenicity of hepatitis B virus envelope antigen expressed by recombinant vaccinia virus. Finding of retention signal in the C-terminal portion of the preS1 domain of subtype adyw., PMID:1759909
Discrimination of hepatitis B virus (HBV) subtypes using monoclonal antibodies to the PreS1 and PreS2 domains of the viral envelope., PMID:1693248
Antibodies to synthetic peptides from the preS1 region of the hepatitis B virus (HBV) envelope (env) protein are virus-neutralizing and protective., PMID:2476893
In vitro immune responses to hepatitis B surface antigen (Pre-S2 and S) following remote infection by hepatitis B virus in humans., PMID:2768432
Hepatitis B virus surface antigen (HBsAg) as carrier for synthetic peptides having an attached hydrophobic tail., PMID:2467197
Immunity to hepatitis B: analysis of antibody and cellular responses in recipients of a plasma-derived vaccine using synthetic peptides mimicking S and pre-S regions., PMID:3349646
Inhibition of albumin binding to hepatitis B virions by monoclonal antibody to the preS2 domain of the viral envelope., PMID:2452108
For research use only. Not for human or drug use.
