Catalog No.
VVV02904
Species reactivity
Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5)
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
Envelope glycoprotein B, gB, gB, UL55
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P13201
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
8F9
SPA14 liposomes combining saponin with fully synthetic TLR4 agonist provide adjuvanticity to hCMV vaccine candidate., PMID:39702373
A temperature-dependent virus-binding assay reveals the presence of neutralizing antibodies in human cytomegalovirus gB vaccine recipients' sera., PMID:37310000
In vivo deglycosylation of recombinant glycoproteins in tobacco BY-2 cells., PMID:37266972
Neutralizing Antibodies Limit Cell-Associated Spread of Human Cytomegalovirus in Epithelial Cells and Fibroblasts., PMID:35215877
Sequencing Directly from Clinical Specimens Reveals Genetic Variations in HCMV-Encoded Chemokine Receptor US28 That May Influence Antibody Levels and Interactions with Human Chemokines., PMID:34704798
Adult and Cord Blood-Derived High-Affinity gB-CAR-T Cells Effectively React Against Human Cytomegalovirus Infections., PMID:32159399
Intrahost Dynamics of Human Cytomegalovirus Variants Acquired by Seronegative Glycoprotein B Vaccinees., PMID:30518646
Turning the tables on cytomegalovirus: targeting viral Fc receptors by CARs containing mutated CH2-CH3 IgG spacer domains., PMID:29422056
Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus., PMID:28854233
Preclinical evaluations of peptide-conjugate vaccines targeting the antigenic domain-2 of glycoprotein B of human cytomegalovirus., PMID:26986197
THY-1 Cell Surface Antigen (CD90) Has an Important Role in the Initial Stage of Human Cytomegalovirus Infection., PMID:26147640
HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation., PMID:24658280
The glycoprotein B disintegrin-like domain binds beta 1 integrin to mediate cytomegalovirus entry., PMID:20660204
Human cytomegalovirus glycoproteins gB and gH/gL mediate epithelial cell-cell fusion when expressed either in cis or in trans., PMID:18815310
The human cytomegalovirus virion possesses an activated casein kinase II that allows for the rapid phosphorylation of the inhibitor of NF-kappaB, IkappaBalpha., PMID:17344282
Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL., PMID:16216889
Animal models of congenital cytomegalovirus infection: an overview of progress in the characterization of guinea pig cytomegalovirus (GPCMV)., PMID:12361755
Quantity of cytomegalovirus DNA in different leukocyte populations during active infection in vivo and the presence of gB and UL18 transcripts., PMID:11424116
Immunogenicity evaluation of DNA vaccines that target guinea pig cytomegalovirus proteins glycoprotein B and UL83., PMID:10892996
Human cytomegalovirus UL144 open reading frame: sequence hypervariability in low-passage clinical isolates., PMID:10559318
Variation within the glycoprotein B gene of human cytomegalovirus is due to homologous recombination., PMID:10374968
Human cytomegalovirus infection of caco-2 cells occurs at the basolateral membrane and is differentiation state dependent., PMID:10233913
Glycoprotein B genotype correlates with cell tropism in vivo of human cytomegalovirus infection., PMID:9580889
For research use only. Not for human or drug use.
