Catalog No.
VVV03807
Species reactivity
Influenza A virus (A/Singapore/H2011.447/2011(H3N2)) (R9U684), Influenza A virus (strain A/Victoria/3/1975 H3N2) (P03435), Influenza A virus (A/Victoria/361/2011(H3N2)) (A0A097PF39)
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, HA
Concentration
7.62 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
R9U684
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
100 mM Pro-Ac, 20 mM Arg, pH 5.0
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
F045-092
A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface., PMID:40391889
An intranasally administered IgM protects against antigenically distinct subtypes of influenza A viruses., PMID:40301359
Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies., PMID:40267182
A monoclonal anti-hemagglutinin stem antibody modified with zanamivir protects against both influenza A and B viruses., PMID:40193611
Identification and characterization of a broadly neutralizing and protective nanobody against the HA1 domain of H5 avian influenza virus hemagglutinin., PMID:40192291
Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of VH3 and VK3 genes., PMID:39894881
Computational design and improvement of a broad influenza virus HA stem targeting antibody., PMID:39884272
Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection., PMID:39788944
Modulating the immunodominance hierarchy of immunoglobulin germline-encoded structural motifs targeting the influenza hemagglutinin stem., PMID:39580804
A Broad Influenza Vaccine Based on a Heat-Activated, Tissue-Restricted Replication-Competent Herpesvirus., PMID:39066341
Broadly protective bispecific antibodies that simultaneously target influenza virus hemagglutinin and neuraminidase., PMID:38899870
Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus., PMID:38782954
Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses., PMID:38670113
Influenza antibody breadth and effector functions are immune correlates from acquisition of pandemic infection of children., PMID:38615070
mRNA vaccines encoding computationally optimized hemagglutinin elicit protective antibodies against future antigenically drifted H1N1 and H3N2 influenza viruses isolated between 2018-2020., PMID:38533508
Combinatorial immune refocusing within the influenza hemagglutinin RBD improves cross-neutralizing antibody responses., PMID:38096052
Fc-Effector-Independent in vivo Activity of a Potent Influenza B Neuraminidase Broadly Neutralizing Antibody., PMID:37515226
Rational design of an influenza-COVID-19 chimeric protective vaccine with HA-stalk and S-RBD., PMID:37394992
Neutralizing and protective murine monoclonal antibodies to the hemagglutinin of influenza H5 clades 2.3.2.1 and 2.3.4.4., PMID:37246149
Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine., PMID:37185989
Epistasis reduces fitness costs of influenza A virus escape from stem-binding antibodies., PMID:37068231
Development of an mRNA vaccine against a panel of heterologous H1N1 seasonal influenza viruses using a consensus hemagglutinin sequence., PMID:37067355
Development of a broadly active influenza intranasal vaccine adjuvanted with self-assembled particles composed of mastoparan-7 and CpG., PMID:37033992
Identification of broad-spectrum neutralizing antibodies against influenza A virus and evaluation of their prophylactic efficacy in mice., PMID:37003306
Analysis of the conserved protective epitopes of hemagglutinin on influenza A viruses., PMID:36875062
Multi-Influenza HA Subtype Protection of Ferrets Vaccinated with an N1 COBRA-Based Neuraminidase., PMID:36680224
Identification of Unique and Conserved Neutralizing Epitopes of Vestigial Esterase Domain in HA Protein of the H9N2 Subtype of Avian Influenza Virus., PMID:36560743
Ferret model to mimic the sequential exposure of humans to historical H3N2 influenza viruses., PMID:36517323
Reverse genetics based H5N2 vaccine provides clinical protection against H5N1, H5N8 and H9N2 avian influenza infection in chickens., PMID:36374710
Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses., PMID:36356572
A broadly protective human monoclonal antibody targeting the sialidase activity of influenza A and B virus neuraminidases., PMID:36329075
Heterosubtypic immune pressure accelerates emergence of influenza A virus escape phenotypes in mice., PMID:36302472
Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses., PMID:36056024
Novel H7N9 influenza immunogen design enhances mobilization of seasonal influenza T cell memory in H3N2 pre-immune mice., PMID:35704783
Characterization of humoral and cell-mediated immunity induced by mRNA vaccines expressing influenza hemagglutinin stem and nucleoprotein in mice and nonhuman primates., PMID:35680500
A broadly neutralizing human monoclonal antibody against the hemagglutinin of avian influenza virus H7N9., PMID:35671181
Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus., PMID:35501328
Characterization of Immune Response towards Generation of Universal Anti-HA-Stalk Antibodies after Immunization of Broiler Hens with Triple H5N1/NA-HA-M1 VLPs., PMID:35458460
A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination., PMID:35115707
Vaccine-Associated Enhanced Respiratory Disease following Influenza Virus Infection in Ferrets Recapitulates the Model in Pigs., PMID:34985999
Evaluation of Next-Generation H3 Influenza Vaccines in Ferrets Pre-Immune to Historical H3N2 Viruses., PMID:34475872
A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells., PMID:34352041
Site-Specific Glycan-Masking/Unmasking Hemagglutinin Antigen Design to Elicit Broadly Neutralizing and Stem-Binding Antibodies Against Highly Pathogenic Avian Influenza H5N1 Virus Infections., PMID:34335603
Universal Influenza Virus Neuraminidase Vaccine Elicits Protective Immune Responses against Human Seasonal and Pre-pandemic Strains., PMID:34160258
Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface., PMID:34156974
Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells., PMID:34145279
First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes., PMID:34078743
Intranasal Nanoparticle Vaccination Elicits a Persistent, Polyfunctional CD4 T Cell Response in the Murine Lung Specific for a Highly Conserved Influenza Virus Antigen That Is Sufficient To Mediate Protection from Influenza Virus Challenge., PMID:34076479
A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge., PMID:34050027
Next-Generation Influenza HA Immunogens and Adjuvants in Pursuit of a Broadly Protective Vaccine., PMID:33805245
For research use only. Not for human or drug use.
