Research Grade Recifercept

Catalog No.

DHC15701

Expression system

Mammalian Cells

Species reactivity

Human

Isotype

Human Fibroblast Growth Factor receptor 3 (FGFR-3, CD333)

Clonality

Monoclonal

Target

FGF1, FGF2, FGF4, FGF6, FGF8, FGF9, FGF10, FGF17, FGF18, FGF19, FGF20 and FGF23

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

PF-07256472, Reciferecept, TA-46

Clone ID

Recifercept

Losartan alters osteoblast differentiation and increases bone mass through inhibition of TGFB signalling in vitro and in an OIM mouse model., PMID:39185375

Natural disease course modeling of achondroplasia to evaluate the efficacy of recifercept in the absence of a placebo control arm in phase II study., PMID:38685585

Juvenile toxicity study of PF-07256472/recifercept, a recombinant human soluble fibroblast growth factor receptor 3, in 2-3-month-old cynomolgus monkeys., PMID:36367445

Longitudinal Imaging of the Skull Base Synchondroses Demonstrate Prevention of a Premature Ossification After Recifercept Treatment in Mouse Model of Achondroplasia., PMID:35229060

In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia., PMID:33370388

Document Download

Research Grade Recifercept.pdf