Catalog No.
PVV02401
Species reactivity
Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant HAdV-5 E1B-55K/E1B-495R (Met1-Gln79).
Tested applications
ELISA: 1:2000-1:8000, IHC: 1:50-1:200, WB: 1:500-1:4000
Target
E1B 55 kDa protein, E1B-55K, E1B protein, large T-antigen, E1B-495R
Concentration
0.29 mg/ml
Purification
Purified by antigen affinity column.
Accession
P03243
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The E3 ubiquitin ligase activity associated with the adenoviral E1B-55K-E4orf6 complex does not require CRM1-dependent export., PMID:21561915
SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PML., PMID:20639899
Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation., PMID:20566845
RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis., PMID:18417565
Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein., PMID:11287579
Viral oncoproteins discriminate between p53 and the p53 homolog p73., PMID:9774648
Bcl-2 blocks p53-dependent apoptosis., PMID:8139558
Multiple pathways for gene activation in rodent cells by the smaller adenovirus 5 E1A protein and their relevance to growth and transformation., PMID:8409938
Enteric adenovirus type 40: expression of E1B mRNA and proteins in permissive and nonpermissive cells., PMID:2145689
For research use only. Not for human or drug use.
