Catalog No.
DHG63702
Expression system
Mammalian Cells
Species reactivity
Human
Isotype
Fusion-[human ACTR-IIB]2-Fc (Fragment constant)
Clonality
Monoclonal
Target
ACTR-IIB, Activin receptor type IIB, Activin receptor type-2B, ACVR2B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13705
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
KER012, RKER-012, RKER012
Clone ID
KER-012
Humoral immunoprofiling identifies novel biomarkers and an immune suppressive autoantibody phenotype at the site of disease in pancreatic ductal adenocarcinoma., PMID:38450186
ACVR1: A Novel Therapeutic Target to Treat Anemia in Myelofibrosis., PMID:38201581
Autoantibodies in the diagnosis, prognosis, and prediction of colorectal cancer., PMID:34528528
Myostatin/Activin Receptor Ligands in Muscle and the Development Status of Attenuating Drugs., PMID:34520530
Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade., PMID:30860875
Updated protocols for the detection of Sotatercept and Luspatercept in human serum., PMID:30203930
Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting., PMID:29193906
Antibody-based strategies for the detection of Luspatercept (ACE-536) in human serum., PMID:28929587
Paired Expression Analysis of Tumor Cell Surface Antigens., PMID:28871274
Rapid Activation of Bone Morphogenic Protein 9 by Receptor-mediated Displacement of Pro-domains., PMID:26677222
Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia., PMID:20036643
Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays., PMID:19638618
For research use only. Not for human or drug use.
