Catalog No.
YVV38801
Expression system
E. coli
Species
African swine fever virus (ASFV)
Protein length
Met1-Ser148
Predicted molecular weight
19.44 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P42485
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Apoptosis regulator Bcl-2 homolog, Ba71V-041, A179L
The evolutionary and genetic patterns of African swine fever virus., PMID:38824981
Deletion of the gene for the African swine fever virus BCL-2 family member A179L increases virus uptake and apoptosis but decreases virus spread in macrophages and reduces virulence in pigs., PMID:37796125
The A179L Gene of African Swine Fever Virus Suppresses Virus-Induced Apoptosis but Enhances Necroptosis., PMID:34960759
Structures and Functional Diversities of ASFV Proteins., PMID:34834930
An insight into the transmission role of insect vectors based on the examination of gene characteristics of African swine fever virus originated from non-blood sucking flies in pig farm environments., PMID:32615970
Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin., PMID:31461953
Investigations of Pro- and Anti-Apoptotic Factors Affecting African Swine Fever Virus Replication and Pathogenesis., PMID:28841179
African Swine Fever Virus: A Review., PMID:28489063
Structural Insight into African Swine Fever Virus A179L-Mediated Inhibition of Apoptosis., PMID:28053104
A179L, a viral Bcl-2 homologue, targets the core Bcl-2 apoptotic machinery and its upstream BH3 activators with selective binding restrictions for Bid and Noxa., PMID:18329683
Inhibition of apoptosis by the African swine fever virus Bcl-2 homologue: role of the BH1 domain., PMID:9123849
African swine fever virus gene A179L, a viral homologue of bcl-2, protects cells from programmed cell death., PMID:8918551
For research use only. Not for human or drug use.
