Catalog No.
PMF71301
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse HSD11B2 (Thr82-Ala331).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, 11-beta-HSD2, 1.1.1.-, Corticosteroid 11-beta-dehydrogenase isozyme 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, Hsd11b2, Hsd11k
Purification
Purified by antigen affinity column.
Accession
P51661
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Microbiota modulates the steroid response to acute immune stress in male mice., PMID:38361932
Utero-placental expression and functional implications of HSD11B1 and HSD11B2 in canine pregnancy†., PMID:36722005
Artificial Neural Network Analysis-Based Immune-Related Signatures of Primary Non-Response to Infliximab in Patients With Ulcerative Colitis., PMID:34992592
Aldosterone-sensitive HSD2 neurons in mice., PMID:30343334
Cortisol Homeostasis in the Epidermis is Influenced by Topical Corticosteroids in Patients with Atopic Dermatitis., PMID:28794569
Glucocorticoid metabolism in the bovine cumulus-oocyte complex matured in vitro., PMID:26519454
Variable expression of 11beta Hydroxysteroid dehydrogenase (11beta-HSD) isoforms in vascular endothelial cells., PMID:18573267
Expression of 11beta-hydroxysteroid dehydrogenase (11betaHSD) proteins in luteinizing human granulosa-lutein cells., PMID:12844344
Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor., PMID:12015312
Clinical relevance of airway 11beta-hydroxysteroid dehydrogenase type II enzyme in asthma., PMID:11934730
In vivo footprinting of the human 11beta-hydroxysteroid dehydrogenase type 2 promoter: evidence for cell-specific regulation by Sp1 and Sp3., PMID:11850421
11beta-hydroxysteroid dehydrogenase type 2 is expressed in the human kidney glomerulus., PMID:11836336
For research use only. Not for human or drug use.
