Catalog No.
PMF71201
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse NUCB2 (Gly51-Leu229).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Nucleobindin-2, DNA-binding protein NEFA, Prepronesfatin, Nesfatin-1, Nucb2, Nefa
Purification
Purified by antigen affinity column.
Accession
P81117
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
"Satiety molecules" - nesfatin-1 and glucagon-like peptide 1 in blood serum in patients with anorexia nervosa and obesity., PMID:40331844
Immunohistochemical determination of the excitatory and inhibitory axonal endings contacting NUCB2/nesfatin-1 neurons., PMID:38157780
Chemogenetic activation of endogenous arginine vasopressin exerts anorexigenic effects via central nesfatin-1/NucB2 pathway., PMID:34134629
Central blockage of nesfatin-1 has anxiolytic effects but does not prevent corticotropin-releasing factor-induced anxiety in male rats., PMID:32736706
Endogenous NUCB2/Nesfatin-1 Regulates Energy Homeostasis Under Physiological Conditions in Male Rats., PMID:32722818
Nesfatin-1 and visfatin expression is associated with reduced atherosclerotic disease risk in patients with rheumatoid arthritis., PMID:29475075
Nesfatin-1 influences the excitability of gastric distension-responsive neurons in the ventromedial hypothalamic nucleus of rats., PMID:27982684
The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) - 1, Nesfatin-1 and anthropometric features in patients with Hashimoto's thyroiditis: a randomized controlled trial., PMID:27852303
High NUCB2 expression level represents an independent negative prognostic factor in Chinese cohorts of non-metastatic clear cell renal cell carcinoma patients., PMID:27806328
Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway., PMID:26937622
Nucleobindin 1 (NUCB1) is a Golgi-resident marker of neurons., PMID:26666627
Nesfatin-1 signaling in the basom edial amygdala modulates the gastric distension-sensitive neurons discharge and decreases gastric motility via melanocortin 3/4 receptors and modified by the arcuate nucleus., PMID:26144374
Nesfatin-1 Suppresses Cardiac L-type Ca²⁺ Channels Through Melanocortin Type 4 Receptor and the Novel Protein Kinase C Theta Isoform Pathway., PMID:25997563
Effects of exogenous nesfatin-1 on gastric distention-sensitive neurons in the central nucleus of the amygdala and gastric motility in rats., PMID:25220707
Expression of nucleobindin 1 (NUCB1) in pancreatic islets and other endocrine tissues., PMID:25038744
A role of nesfatin-1/NucB2 in dehydration-induced anorexia., PMID:24829503
Nesfatin-1/nucleobindin-2 like immunoreactivity in the olfactory system, brain and pituitary of frog, Microhyla ornata., PMID:24768694
Central nesfatin-1 influences the excitability of ghrelin-responsive gastric distension neurons in the arcuate nucleus and reduces gastric motility in rats., PMID:24289827
Role of nesfatin-1 in a rat model of visceral hypersensitivity., PMID:23801843
Nesfatin-1 inhibits ovarian epithelial carcinoma cell proliferation in vitro., PMID:23764403
Central and peripheral expression and distribution of NUCB2/nesfatin-1., PMID:23537079
NEFA/nucleobindin-2 is a target autoantigen of the anti-Wa antibody and is associated with transfer RNA., PMID:22270345
Restraint stress alters the secretory activity of neurons co-expressing urocortin-1, cocaine- and amphetamine-regulated transcript peptide and nesfatin-1 in the mouse Edinger-Westphal nucleus., PMID:20043894
Molecular characterisation and expression analysis of SEREX-defined antigen NUCB2 in gastric epithelium, gastritis and gastric cancer., PMID:19351608
Molecular characterisation and expression analysis of SEREX-defined antigen NUCB2 in gastric epithelium, gastritis and gastric cancer., PMID:30256860
[Transfer RNA-associated anti-Wa antibody in patients with scleroderma and the target antigen NEFA/Nucleobindin-2]., PMID:17603255
Identification of nesfatin-1 as a satiety molecule in the hypothalamus., PMID:17036007
Serological identification and expression analysis of gastric cancer-associated genes., PMID:12087473
Golgi retention of human protein NEFA is mediated by its N-terminal Leu/Ile-rich region., PMID:11749975
Human protein NEFA, a novel DNA binding/EF-hand/leucine zipper protein. Molecular cloning and sequence analysis of the cDNA, isolation and characterization of the protein., PMID:7811391
For research use only. Not for human or drug use.
