Anti-IGF2BP2 Polyclonal Antibody

Catalog No.

PHJ91501

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IGF2BP2 (Ser141-Pro384).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Hepatocellular carcinoma autoantigen p62,IMP2,IGF-II mRNA-binding protein 2,IMP-2,VICKZ2,VICKZ family member 2,IGF2BP2,IGF2 mRNA-binding protein 2,Insulin-like growth factor 2 mRNA-binding protein 2

Purification

Purified by antigen affinity column.

Accession

Q9Y6M1

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

IGF2BP2 inhibits invasion and migration of clear cell renal cell carcinoma via targeting Netrin-4 in an m6A-dependent manner., PMID:38780170

A1BG-AS1 promotes adriamycin resistance of breast cancer by recruiting IGF2BP2 to upregulate ABCB1 in an m6A-dependent manner., PMID:38007504

m6A Regulator-mediated RNA Methylation Modulates Immune Microenvironment of Hepatitis B Virus-related Acute Liver Failure., PMID:37256461

Decreased DANCR contributes to high glucose-induced extracellular matrix accumulation in human renal mesangial cell via regulating the TGF-β/Smad signaling., PMID:37052733

A comprehensive immunohistochemical analysis of IMP2 and IMP3 in 542 cases of ovarian tumors., PMID:36740684

microRNA-20b-5p overexpression combing Pembrolizumab potentiates cancer cells to radiation therapy via repressing programmed death-ligand 1., PMID:34968160

Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression., PMID:34809621

RNA Demethylase FTO Mediated RNA m6A Modification Is Involved in Maintaining Maternal-Fetal Interface in Spontaneous Abortion., PMID:34350169

The Prevalence of Cancer-Associated Autoantibodies in Patients with Gastric Cancer and Progressive Grades of Premalignant Lesions., PMID:28768706

Anti-cytoplasmic Autoantibodies in Hodgkin's Lymphoma., PMID:28164609

Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer., PMID:27700103

p62/IMP2 stimulates cell migration and reduces cell adhesion in breast cancer., PMID:26416451

Autoimmune Response to IGF2 mRNA-Binding Protein 2 (IMP2/p62) in Breast Cancer., PMID:25721883

The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer., PMID:25068994

The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis., PMID:24755648

Humoral autoimmune response to IGF2 mRNA-binding protein (IMP2/p62) and its tissue-specific expression in colon cancer., PMID:23421499

IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling., PMID:23257922

IGF2BP2 alternative variants associated with glutamic acid decarboxylase antibodies negative diabetes in Malaysian subjects., PMID:23029108

Two isoforms of the mRNA binding protein IGF2BP2 are generated by alternative translational initiation., PMID:22427968

Autoantibodies to IGF-II mRNA binding protein p62 and overexpression of p62 in human hepatocellular carcinoma., PMID:12849008

Autoimmune responses to mRNA binding proteins p62 and Koc in diverse malignancies., PMID:11465943

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Anti-IGF2BP2 Polyclonal Antibody.pdf